supported by National Key Research and Development Program of China(No.2021YFB3800800 to D.C.and L.T);the National Natural Science Foundation of China(No.82030067,82250710174,82161160342,82060406,82360429 and 82172397 to D.C.and L.T.and Y.C.);the Hong Kong RGC(China)(No.HKU-17101821 to W.W.L and D.C.);Shenzhen Science and Technology Program(Guangdong,China)(No.JSGGKQTD20210831174330015 to H.P.and D.C.);Natural Science Foundation of Guangxi(No.2022JJA141126 to Y.C.).
Osteoarthritis (OA) is a debilitating chronic joint disease affecting large populations of patients, especially the elderly. The pathological mechanisms of OA are currently unknown. Multiple risk factors are involved ...
supported by grants from the Chinese Academy of Medical Sciences Innovation Fund for Medical Sciences(No.2021-1-I2M-018);the Haihe Laboratory of Cell Ecosystem Innovation Fund(No.22HHXBSS00012);the National Natural Science Foundation of China(Nos.81730078 and 81872287)
Background:Liver cancer is largely resistant to chemotherapy.This study aimed to identify the effective chemotherapeutics forβ-catenin-activated liver cancer which is caused by gain-of-function mutation of catenin be...