云南高校图书馆联盟文献共享服务平台- MYOC

MYOC: 作品数：21被引量：48H指数：5; 导出分析报告; 相关领域：医药卫生更多>>; 相关作者：周新王建文田艳丽郑建秋季建更多>>; 相关机构：武汉大学首都医科大学南方医科大学天津医科大学更多>>; 相关期刊：《International Journal of Ophthalmology(English edition)》《Chinese Medical Journal》《中国生物制品学杂志》《当代医药论丛》更多>>; 相关基金：国家自然科学基金哈尔滨医科大学附属第一医院科研基金黑龙江省青年科学基金湖北省自然科学基金更多>>

Clinical and genetic analysis of Ser341Pro MYOC variant in a Korean family with primary open angle glaucoma被引量：1: 《International Journal of Ophthalmology(English edition)》2020年第11期1689-1696,共8页Sangwoo Moon Namhee Kim Jiwoong Lee; Supported by Patient-Centered Clinical Research Coordinating Center funded by the Ministry of Health&Welfare,Republic of Korea(No.HI19C0481,No.HC19C0276).; AIM:To report the first discovery of Ser341Pro myocilin(MYOC)variant in Korea and analyze its clinical characteristics and genetic significance.METHODS:Ten family members from three generations participated in this st...; 关键词：Ser341Pro variant primary open angle glaucoma KOREAN

对江浙地区高度近视眼人群进行MYOC基因突变的调查: 《当代医药论丛》2020年第5期69-71,共3页章立新洪楠叶蓓夏建华沈晔; 浙江省教育厅科研项目(Y201636338);浙江省教育厅2015年度高等学校国内访问工程师校企合作资助项目(项目编号:130)。; 目的:调查江浙地区高度近视眼人群MYOC基因突变的情况,为研究和防治近视眼提供参考。方法:选取2015年10月至2016年10月期间在浙江大学医学院附属第一医院住院治疗的74例浙江籍近视眼患者作为研究对象。将这74例患者分为高度近视眼组(n=...; 关键词：MYOC基因高度近视基因突变

Evaluating correlation between the ocular biometry and genetic variants of MYOC and ABCA1 with primary angleclosure glaucoma in a cohort from northern China: 《International Journal of Ophthalmology(English edition)》2019年第8期1317-1322,共6页Shao-Lin Wang Shun-Yu Piao Man-Yun Xu Wen Zhang Jian-Qing Ma Juan Hao Hao Chi Zhong-Qi Xue Shao-Ping Ha Wen-Juan Zhuang; Supported by the National Natural Science Foundation of China(No.81460093);the Ningxia Nature Science Funding from the Department of Science and Technology of Ningxia Hui Autonomous Region(No.NZ16194); AIM: To investigate whether the gene variants in MYOC and ABCA1 are associated with primary angle-closure glaucoma(PACG) and anterior chamber depth(ACD) and axial length(AL) in samples from northern China. METHODS: Th...; 关键词：MYOC ABCA1 PRIMARY ANGLE-CLOSURE GLAUCOMA anterior chamber depth axial length single NUCLEOTIDE polymorphisms

AB024.Phenotypic dissection of myocilin(MYOC)-induced glaucoma reveals that the modifier of glaucoma 1(MOG1)locus encodes a gene which prevents ocular hypertension: 《Annals of Eye Science》2019年第1期199-199,共1页Vincent Raymond Pascal Belleau Rose Arseneault Jean-Louis Anctil Gilles Côté Marcel Amyot Patrick Laplante Laurent Lamalice Stéphane Dubois Fahed Elian Michael A.Walter Québec Glaucoma Network; Background:Pathogenic mechanisms leading to open-angle glaucoma(OAG)are genetically complex.They involve neuroinflammation,elevation of intra-ocular pressures(IOP)and optic nerve hypersensitivity to cellular stresses....; 关键词：BLINDNESS GLAUCOMA genetics MODIFIER MYOCILIN

A recurrent G367R mutation in MYOC associated with juvenile open angle glaucoma in a large Chinese family被引量：8: 《International Journal of Ophthalmology(English edition)》2018年第3期369-374,共6页Yi-Hua Yao Ya-Qin Wang Wei-Fang Fang Liu Zhang Ju-Hua Yang Yi-Hua Zhu; Supported by Natural Science Foundation of China(No.81270999;No.81570870);Professor Academic Development Fund of Fujian Medical University(No.JS14019); AIM： To identify the mutations of MYOC, OPTN, CYPIB1 and WDR36 in a large Chinese family affected by juvenile open angle glaucoma （JOAG）. METHODS： Of 114 members of one family were recruited in this study. Blood ...; 关键词：MYOC gene mutantion GLAUCOMA

遗传基因组学方法对Myoc基因调控网络的研究被引量：2: 《中华实验眼科杂志》2013年第9期851-854,共4页陆宏陆璐管怀进陈辉张俊芳胡楠帅捷; 江苏省自然科学基金项目（BK2008186）;南通市社会事业创新与示范计划项目（HS2011005）; 背景原发性开角型青光跟（POAG）和高度近视的发病机制复杂，可能有较多致病基因及致病相关基因参与，构建基因调控网络有助于揭示发病机制。目的采用遗传基因组学方法研究Myoc基因的调控网络，探索其在POAG中的可能作用机制。方法Affym...; 关键词：基因组学 Myoc基因网络原发性开角型青光眼高度近视 BXD RI小鼠

Single nucleotide polymorphism of MYOC affected the severity of primary open angle glaucoma被引量：2: 《International Journal of Ophthalmology(English edition)》2013年第3期264-268,共5页Xiao-Min Zhou Yan Yin Ning Fan Hong-Bo Cheng Xiao-Hong Li Yun Wang Wen-Han Yu Su-Ping Cai Xu-Yang Liu; National Nature Science Foundation of China (No.81170851); AIM: To detect the mutations in two candidate genes, myocilin (MYOC ) and cytochrome P450 1B1 (CYP1B1 ), in a Chinese family with primary open angle glaucoma (POAG). ·METHODS:Thefamilywascomposedofthreemembers, the p...; 关键词：primary open angle glaucoma MYOCILIN MUTATION D384N T353I

NT-proBNP联合CK-MB、MYO、cTnI对急性心肌梗死的临床价值分析被引量：6: 《中国医疗前沿》2011年第10期65-66,共2页冯波刘丽丽姜晓燕鹿梅肖古华; 目的探讨血清NT-proBNP联合CK-MB、MYO、cTnI检测对急性心肌梗死的临床价值。方法测定113例急性心肌梗死患者和127例健康体检者血清NT-proBNP、CK-MB、MYO、cTnI含量,各组之间相互比较。结果急性心肌梗死患者血清中NT-proBNP、CK-MB、MY...; 关键词：NT-PROBNP CK-MB MYOC TNI 急性心肌梗死

原发性开角型青光眼MYOC—TIGR基因突变研究被引量：6: 《中华眼科杂志》2011年第2期122-128,共7页陈建华徐亮李杨董冰; 目的筛选并研究原发性开角型青光眼（POAG）小梁网糖皮质激素诱导反应蛋白MYOC-TIGR基因突变情况。方法病例对照研究。抽取2002年1至12月就诊并诊断为POAG患者118例和150例非POAG对照者的外周静脉血4-8ml，采用酚-氯仿抽提全基因组DNA...; 关键词：青光眼开角型 DNA突变分析细胞支架蛋白质类眼蛋白质类多态性单核苷酸

原发性开角型青光眼致病基因小鼠MYOC Pro356Leu突变型质粒构建及鉴定: 《Eye Science》2010年第1期57-61,共5页李春梅卓业鸿陈梦飞孙雪荣祁影葛坚; 中国国家自然科学基金项目资助(30600695/C030309); 目的:构建小鼠MYOC Pro356Leu突变型质粒及鉴定。方法:1.将含有红重组酶基因的质粒pKD46电击入RP23-180F15 BAC克隆。2.利用PCR扩增pStart-K载体,将PCR产物电穿孔入RP23-180F15 BAC红色重组细菌的MYOC基因组片段。3.PCR扩增mMyoc AfeⅠ...; 关键词：原发性开角型青光眼 MYOCPro356Leu突变质粒构建

MYOC