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NADP: 作品数：92被引量：259H指数：8; 导出分析报告; 相关领域：生物学更多>>; 相关作者：郑裕国顾采琴叶济宇程峰薛亚平更多>>; 相关机构：浙江大学浙江工业大学中国科学院上海生命科学研究院江南大学更多>>; 相关期刊：更多>>; 相关基金：国家自然科学基金博士科研启动基金中央高校基本科研业务费专项资金安徽省优秀青年科技基金更多>>

The combination of SLC7A11 inhibitor and oridonin synergistically inhibits cervical cancer cell growth by decreasing the NADPH/NADP^(+) ratio: 《Genes & Diseases》2025年第1期137-140,共4页Yajie Liu Pengxing He Xubin Ma Yingqi Tian Yu Zhang Yang Wang Yingjie Jia Hongmin Liu Ying Liu Yichao Xu; supported by the National Key Research and Development Project(China)(No.2018YFE0195100);the National Natural Science Foundation of China(No.82020108030);the Key Scientific Research Projects in Colleges and Universities of Henan Province,China(No.23A350007).; SLC7A11,as the core component of system xc,protects cancer cells from oxidative-stress-induced cell death like ferroptosis by mediating cystine uptake.Recent studies revealed that SLC7A11 is widely overexpressed in va...; 关键词：cervical HERBAL synergistic

新疆齿肋赤藓铁氧还蛋白-NADP^(+)还原酶(FNR)基因的克隆与表达分析: 《种子》2025年第2期1-10,共10页薛山杨博毅但丁孙迎涛李鸿彬张霞卓露; 国家自然科学基金(32360097);新疆生产建设兵团人才发展专项(CZ00150102)。; 铁氧还蛋白-NADP^(+)还原酶(Ferredoxin-NADP^(+)Reductase,FNR)负责催化光合线性电子传递的最后一步反应,在植物生长发育和胁迫信号通路起到关键作用。为探究齿肋赤藓(Syntrichia caninervis Mitt.)FNR基因的功能、表达特性和该基因影...; 关键词：齿肋赤藓 ScFNR2基因生物信息学分析亚细胞定位蛋白互作网络

植物NAD(P)^+的生物合成及其生物学功能研究进展: 《植物学报》2025年第1期114-131,共18页胡海涛武越杨玲; 浙江省自然科学基金(No.LY19C130003)。; 烟酰胺腺嘌呤二核苷酸(NAD^(+))和烟酰胺腺嘌呤二核苷酸磷酸(NADP^(+))是植物核心能量代谢、生长发育以及胁迫应答的整合者,可直接或间接影响多种关键的细胞功能。作为细胞代谢的基石,胞内NAD(P)^(+)稳态对于维持植物正常能量代谢、生...; 关键词：NAD^(+) NADP^(+) 生物合成生物学功能

Homeostatic regulation of NAD(H)and NADP(H)in cells: 《Genes & Diseases》2024年第5期285-299,共15页Luojun Chen Xiaoke Xing Pingfeng Zhang Lulu Chen Huadong Pei; Nicotinamide adenine dinucleotide(NAD^(+))/reduced NAD^(+)(NADH)and nicotinamide adenine dinucleotide phosphate(NADP^(+))/reduced NADP^(+)(NADPH)are essential metabolites involved in multiple metabolic pathways and ce...; 关键词：MESH1 NAD(H) NADK NADP(H) Nocturnin

Remote Control of Bovine Catalase Activity with Specific Frequencies of Human and Bovine Catalase with and without Bound NADP+: 《Advances in Enzyme Research》2024年第2期17-34,共18页Thibaud Etienne d’Oultremont; Remote control enzyme technology is widely used today through resonance. In this study, we showed that the use of frequencies of the catalase enzyme itself to increase enzymatic rate is successful not only in test tub...; 关键词：Remote Control CATALASE Frequency Rate Promoting Vibration (RPV) NADP

GapN诱导型表达小白链霉菌的构建及其对ε-聚赖氨酸生产的影响: 《滨州医学院学报》2023年第4期241-245,共5页毛佳琪张敏代文娟秦加阳; 国家自然科学基金(31970086)。; 目的构建NADP依赖型三磷酸甘油醛脱氢酶(GapN)诱导型表达的小白链霉菌基因工程菌,研究GapN不同表达水平对ε-聚赖氨酸(ε-PL)生产的影响。方法化学合成来自变异链球菌的gapN基因,利用DNA无缝克隆技术构建GapN诱导型表达载体pSET152-Cel-...; 关键词：小白链霉菌 Ε-聚赖氨酸 NADP依赖型3-磷酸甘油醛脱氢酶诱导表达 NADPH

过量表达气囊蛋白强化茂原链霉菌合成胰蛋白酶: 《食品与发酵工业》2023年第14期1-8,共8页苏莹莹刘松; 国家重点研发计划项目(2019YFA0706900);国家自然科学基金面上项目(32071474)。; 气囊蛋白(gas vesicle protein, Gvp)组成的气体囊泡存在于蓝藻、嗜盐古菌等微生物中,为细胞提供浮力或抗胁迫能力。尽管gvp基因簇广泛存在于链霉菌,但其功能尚不明确。在该研究中,分别在茂原链霉菌(Streptomyces mobaraensis)DSM40587...; 关键词：气囊蛋白基因簇 Streptomyces mobaraensis 过量表达胰蛋白酶 ATP NADPH/NADP^(+)

高山被孢霉NADP^(+)依赖型异柠檬酸脱氢酶的异源表达与活性分析被引量：1: 《食品与发酵工业》2023年第2期13-19,共7页王旭旭孙晓琪陈海琴赵建新陈卫唐鑫; 国家自然科学基金青年基金(31901659)。; 产油真菌胞质中NADP^(+)依赖型异柠檬酸脱氢酶(isocitrate dehydrogenase,IDH)能够为脂肪酸合成提供还原力,前期研究表明高山被孢霉的异柠檬酸脱氢酶4(Mortierella alpina isocitrate dehydrogenase4,MaIDH4)对脂质积累有积极的影响。...; 关键词：高山被孢霉异柠檬酸脱氢酶异源表达酶活性酶产量

Monitoring NAD(H) and NADP(H) dynamics during organismal development with genetically encoded fluorescent biosensors: 《Cell Regeneration》2022年第1期44-54,共11页Ting Li Yejun Zou Shuning Liu Yi Yang Zhuo Zhang Yuzheng Zhao; This research is supported by National Key Research and Development Program of China(2019YFA0904800 to Y.Zhao);NSFC(32030065,92049304,32121005 to Y.Zhao,31901033 to T.L.);Research Unit of New Techniques for Live-cell Metabolic Imaging(Chinese Academy of Medical Sciences,2019RU01,2019-I2M-5-013 to Y.Zhao);Shanghai Frontiers Science Center of Optogenetic Techniques for Cell Metabolism(Y.Zhao);Innovative research team of high-level local universities in Shanghai,the Shanghai Science and Technology Commission(19YF1411300 to T.L.);China Postdoctoral Science Foundation(2019 M651413 to T.L.);the State Key Laboratory of Bioreactor Engineering,the Fundamental Research Funds for the Central Universities.; Cell metabolism plays vital roles in organismal development,but it has been much less studied than transcriptional and epigenetic control of developmental programs.The difficulty might be largely attributed to the lac...; 关键词：Cell metabolism NAD(H)and NADP(H) Genetically encoded fluorescent sensors Real-time monitoring Organismal development

Downregulation of NADPH-cytochrome P450 reductase via RNA interference increases the susceptibility of Acyrthosiphon pisum to desiccation and insecticides: 《Insect Science》2022年第4期1105-1119,共15页Jian-Wen Qiao Yong-Liang Fan Bing-Jin Wu Tian-Tian Bai Ying-Hao Wang Zhan-Feng Zhang Dun Wang Tong-Xian Liu; This research was supported by the National Natural Sci-ence Foundation of China(31772533);Shaanxi Key Project of Science and Tchnology(2020zdzx03-03-02).; Nicotinamide adenine dinucleotide phosphate(NADPH)-cytochrome P450 reductase(CPR)is involved in the metabolism of endogenous and exogenous substances,and detoxification of insecticides.RNA interference(RNAi)of CPR in ...; 关键词：Acyrthosiphon pisum desiccation tolerance lhydrocarbon insecticide sus-ceptibility NADPH-cytochrome P450 reductase

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