National Key Project"Prevention and Therapy of Fatal Infectious Diseases such AIDS&Viral Hepatitis:Popularization and application of diagnosis and treatment of Belt and Road HIV/AIDS with Traditional Chinese Medicine"(No.2018ZX10101001-005-001);the National Key Project"The Development of New Pharmaceuticals:the Construction of Platform for Clinical Evaluation of New Antiretroviral Therapy-Clinical trial phase I-IV"(No.2017ZX09304027-001-010);the Thirteen-fifth Key Project"The Study of Construction of Representative Areas for Prevention and Therapy of Fatal Infectious Diseases such AIDS&Viral Hepatitis in Chaoyang District,Beijing"(No.2018ZX10715-005);the National Natural Science Foundation"The Study for Delay and Persistent Poor Immune Reconstitution in HIV/AIDS Patients"(No.81672000);Project from Beijing Municipal Committee of Science&Technology"The study of HIV/HBV co-infection"(No.D161100000416004);Project for Capital Characteristics"The study for blood concentration of efavirenz influenced by rifampin in HIV/TB co-infected patient"(No.Z171100001017053);The Key Project from Beijing Hospital Authority(No.DFL20191802);Major Project of Beijing Municipal Science and Technology Committee(No.D161100000416003)。
Background Studies have reported that low bone mineral density(BMD)is prevalent in human immunodeficiency virus(HIV)-infected patients;however,the factors that contribute to HIV-related BMD changes are yet to be fully...
This study was supported by grants from the Major Science and Technology Special Project of China Thirteenth Five-year Plan(No.2013ZX10002004,No.2017ZX10203202-003-007);supported by the Shanghai Science and Technology Development Fund(No.17411969500);the Shanghai Public Health Clinical Center Fund(No.XKJS-2019HBV-06,No.KYGW-2019-32).
Background:The efficacy of entecavir(ETV)add-on peg-interferon therapy compared with ETV monotherapy in treatment-naive hepatitis B virus(HBV)patients remains controversial.We investigated whether adding peg-interfero...
Background: Intravenous (IV) oxycodone has been used at induction to prevent an intubation reaction. The aims of the current study were to calculate the median effective dose (ED50) and the 95% effective dose (E...
Background: Estimating the grades of liver inflammation is critical in the determination ofantiviral therapy in patients chronically infected with hepatitis B virus (HBV). The aim of this study was to investigate t...
Background:Entecavir (ETV) has been shown to be effective in randomized controlled trials in highly selected patients with hepatitis B virus (HBV) infection.This study aimed to evaluate the efficacy of ETV in chr...
This study was supported by the National Natural Science Foundation of China (No. 81071372), the National Key Technologies R and D Program for the 11th Five-year Plan (No. 2008ZX10001-006), the National Key Technologies R and D Program for the 12th Five-year Plan (No. 2012ZX10001003-001), and the Key Clinical Program of the Ministry of Health (2010-2012).
Background:Among HlV-infected patients initiating antiretroviral therapy (ART),early changes in CD4+ T-cell subsets are well described.However,HIV-infected late presenters initiating treatment present with a subop...
grants from the China Postdoctoral Science Foundation funded project,the Development of Medical Science and Technology Project of Shandong Province,the Natural Science Foundation of Shandong Province,the science and technology fund of Tianjin Health Bureau
Background: This study aimed to observe the differences in brain gray matter volume in drug-naive female patients after the first episode of major depression with and without stressful life events (SLEs) before the...
The studies of the natural progression of Parkinson's disease (PD) in Chinese populations have been lacking. To address this issue and obtain a preliminary data, we conducted a PD progression assessment in 15 adult...
Background Adoptive cell transfer (ACT) immunotherapy has been used clinically for years to treat malignancies.Improving the killing efficiency of effector cells,such as tumor-specific cytotoxic T lymphocytes (CTLs...
The research was partly completed when WANG Zhi-ren was in Institute of Mental Health of Peking University as a Ph.D candiadate, now he works in Beijing Hui-Long-Guan Hospital. This work was supported by grants from the National Basic Research Program of China (973 Program: 2007BC512307), the Capital Medical Development Fund (2009-3148), the National Natural Science Foundation of China (81000579) and the Beijing Municipal Science & Technology Commission (No. D0906001040191).
Background Patients with schizophrenia have prominent abnormality in information processing that can be observed by measures of prepulse inhibition (PPI) of acoustic startle reflex and PPI deficits have been conside...