云南高校图书馆联盟文献共享服务平台- NCI

NCI: 作品数：420被引量：1035H指数：14; 导出分析报告; 相关领域：医药卫生更多>>; 相关作者：范晓云严小军徐继林叶芳挺陆兆双更多>>; 相关机构：安徽医科大学安徽医科大学第一附属医院广西医科大学广州医科大学更多>>; 相关期刊：更多>>; 相关基金：国家自然科学基金中国博士后科学基金博士科研启动基金安徽省高校省级自然科学研究项目更多>>

Endoplasmic reticulum stress and forkhead box protein O1 inhibition mediate palmitic acid and high glucose-inducedβ-cell dedifferentiation: 《World Journal of Diabetes》2025年第5期216-233,共18页Li-Kun Wang Chu-Chu Kong Ting-Yan Yu Hui-Song Sun Lu Yang Ying Sun Ming-Yu Li Wei Wang; Supported by the Natural Science Foundation of China,No.81471081;the Natural Science Foundation of Fujian Province,No.2023D009;the Natural Science Foundation of Xiamen City,No.3502Z202373104 and No.3502Z20227162;Scientific Research Foundation for Advanced Talents,Xiang’an Hospital of Xiamen University,No.PM201809170005。; BACKGROUND Type 2 diabetes mellitus is characterized by pancreaticβ-cell dysfunction and insulin resistance.Studies have suggested thatβ-cell dedifferentiation is one of the pathogeneses ofβ-cell dysfunction,but th...; 关键词：β-cell dedifferentiation High glucose and palmitic acid Forkhead box O1 RNA-sequencing Endoplasmic reticulum stress

Osteosarcopenia and geriatric hip fractures:Current concepts: 《World Journal of Orthopedics》2025年第3期35-40,共6页Theodoros Tosounidis Lefteris Manouras Byron Chalidis; According to World Health Organization,one in six people will be older than 60 by 2030.The rising life expectancy is anticipated to contribute to a subsequent increase of geriatric fractures worldwide.Osteosarcopenia,...; 关键词：Osteosarcopenia Hip fracture Fragility fracture MORTALITY RNA-sequencing PROTEOMICS Muscle-bone crosstalk

甘露醇促进人肺鳞癌细胞系NCI-H292凋亡: 《基础医学与临床》2025年第3期336-340,共5页李黄羿黄道航张文玉黄鼎铭黄其春; 2022年度广西高校中青年教师科研基础能力提升项目(2022KY0106);2022年度广西壮族自治区卫生健康委西医类自筹经费科研课题(Z-A20220676)。; 目的探讨20%甘露醇注射液对人肺鳞癌细胞系NCI-H292增殖和凋亡的作用及其可能机制。方法使用20%及以下不同浓度甘露醇处理NCI-H292细胞,CCK-8法检测NCI-H292细胞增殖和活性;流式细胞测量术检测细胞凋亡;Western blot检测线粒体凋亡途径...; 关键词：甘露醇肺鳞癌凋亡 BCL-2 BAX

松萝酸对A549和NCI-H358细胞增殖、凋亡及自噬的影响: 《安徽医科大学学报》2025年第3期455-462,共8页李新伟王延婷李瑞雪白慧敏刘锦龙; 内蒙古自治区自然科学基金项目(编号:2020LH08006)。; 目的探究松萝酸(UA)对肺癌A549和NCI-H358细胞增殖、细胞周期、凋亡和自噬的影响。方法 CCK-8法检测UA对两种肺癌细胞增殖抑制作用。流式细胞术检测UA对两种肺癌细胞周期阻滞作用。DCFH-DA探针法和流式细胞术检测UA诱导两种肺癌细胞生...; 关键词：UA A549 NCI-H358 细胞周期活性氧凋亡自噬

Pro-resolving lipid mediator reduces amyloid-β42–induced gene expression in human monocyte–derived microglia: 《Neural Regeneration Research》2025年第3期873-886,共14页Ying Wang Xiang Zhang Henrik Biverstål Nicolas GBazan Shuai Tan Nailin Li Makiko Ohshima Marianne Schultzberg Xiaofei Li; supported by the China Scholarship Council(to YW);the Swedish Research Council,No.2018-02601(to MS);the Alzheimer Foundation,No.AF-980695(to MS);the Stockholm County Council,No.RS2020-0731(to MS);the Foundation of Old Servants(to MS);the Gun and Bertil Stohne Foundation(to MS);the?hlén Foundation,No.233055(to MS);The Swedish Fund for Research without Animal Experiments(to MS);the Swedish Dementia Foundation(to MS);the Brain foundation,No.FO2022-0131(to MS)。; Specialized pro-resolving lipid mediators including maresin 1 mediate resolution but the levels of these are reduced in Alzheimer's disease brain, suggesting that they constitute a novel target for the treatment of Al...; 关键词：Alzheimer's disease amyloid-β maresin MICROGLIA MONOCYTE NEUROINFLAMMATION resolution RNA-sequencing specialized pro-resolving lipid mediator

Profiling and bioinformatics analyses of circular RNAs in myocardial ischemia/reperfusion injury model in mice: 《World Journal of Cardiology》2025年第1期65-77,共13页Jiao-Ni Wang Ying-Ying Zhou Yong-Wei Yu Jun Chen; Supported by Zhejiang Provincial Natural Science Foundation of China,No.LQ23H020004;The Medical and Health Research Project of Zhejiang province,No.2024KY983;Basic Medical Health Technology Project of Wenzhou Science and Technology Bureau,No.Y20210818 and No.Y20210140.; BACKGROUND Myocardial ischemia/reperfusion(I/R)injury,which is associated with high morbidity and mortality,is a main cause of unexpected myocardial injury after acute myocardial infarction.However,the underlying mech...; 关键词：Rna-sequencing Circular RNA MicroRNA CeRNA Myocardial ischemia/reperfusion Bioinformatics analyses

Return to work in young and middle-aged colorectal cancer survivors:Factors influencing self-efficacy,fear,resilience,and financial toxicity: 《World Journal of Gastroenterology》2025年第1期79-92,共14页Dan Hu Yue Li Hua Zhang Lian-Lian Wang Wen-Wen Liu Xin Yang Ming-Zhao Xiao Hao-Ling Zhang Juan Li; Supported by the Chongqing Medical University Program for Youth Innovation in Future Medicine,No.W0019;Chongqing Municipal Education Commission’s 14th Five-Year Key Discipline Support Project,No.20240101 and No.20240102。; BACKGROUND Return to work(RTW)serves as an indication for young and middle-aged colorectal cancer(CRC)survivors to resume their normal social lives.However,these survivors encounter significant challenges during their...; 关键词：Return to work Colorectal neoplasms Return-to-work self-efficacy Fear of progression Family resilience Financial toxicity

Transcriptome analysis reveals the genetic basis of crest cushion formation in duck: 《Journal of Integrative Agriculture》2024年第12期4172-4185,共14页Lan Huang Qixin Guo Yong Jiang Zhixiu Wang Guohong Chen Guobin Chang Hao Bai; supported by the earmarked fund for CARS,China(CARS-42);the earmarked fund for Jiangsu Agricultural Industry Technology System,China(JATS(2022)331);the Jiangsu Key Research and Development Program,China(BE2021332)。; The Chinese crested duck is a unique duck breed having a bulbous feather shape on its duck head.However,the mechanisms involved in its formation and development are unclear.In the present study,RNA sequencing analysis...; 关键词：crested duck RNA-sequencing weighted gene co-expression network analysis differentially expressed genes

柠檬醛通过EGFR信号通路抑制NCI-H1975细胞增殖: 《食品研究与开发》2024年第21期63-67,共5页朱威巍聂妍翁大志李艳丽王宣军黄业伟范源洪; 云南绿色食品国际合作研究中心重大科技专项(2019ZG00903)。; 该文探究柠檬醛是否通过表皮生长因子受体(epidermal growth factor receptor,EGFR)信号通路诱导非小细胞肺癌(non-small cell lung cancer,NSCLC)系中NCI-H1975细胞增殖。主要采用噻唑蓝(methyl thiazolyl tetrazolium,MTT)法检测细胞...; 关键词：柠檬醛 NCI-H1975 表皮生长因子受体细胞增殖细胞凋亡

Dissection of molecular mechanisms of liver injury induced by microcystin-leucine arginine via single-cell RNA-sequencing: 《Journal of Environmental Sciences》2024年第11期164-179,共16页Yunmeng Bai Yali Song Miaoran Li Jinhuan Ou Hong Hu Nan Xu Min Cao SiyuWang Lin Chen Guangqing Cheng Zhijie Li Gang Liu Jigang Wang Wei Zhang Chuanbin Yang; supported by the National Key Research and Development Program of China(Nos.2020YFA0908000 and 2022YFC2303600);the Guangdong-Dongguan Joint Fund Regional Cultivation Project(No.2021B1515140033);the Dongguan Science and Technology of Social Development Program(No.20221800905732);the National Natural Science Foundation of China(Nos.82074098,82374063,82274182,81841001,and 82173914);the Science and Technology Foundation of Shenzhen(Shenzhen Clinical Medical Research Center for Geriatric Diseases),Shenzhen Science and Technology Innovation Commission(Nos.JCYJ20220818102613029,JCYJ20210324114014039,and JCYJ20210324115800001);Guangdong Basic and Applied Basic Research Foundation(No.2020A1515110549);the Innovation Team and Talents Cultivation Program of National Administration of Traditional Chinese Medicine(No.ZYYCXTD-C-202002);Shenzhen Governmental Sustainable Development Fund(No.KCXFZ20201221173612034);Shenzhen key Laboratory of Kidney Diseases(No.ZDSYS201504301616234);Shenzhen Fund for Guangdong Provincial High-level Clinical Key Specialties(No.SZGSP001).; The occurrence of poisoning incidents caused by cyanobacterial blooms has aroused wide public concern.Microcystin-leucine arginine(MC-LR)is a well-established toxin produced by cyanobacterial blooms,which is widely di...; 关键词：MC-LR Liver toxicity Single-cell RNA sequencing Immune response Inflammatory responses

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