NERVE_GROWTH_FACTOR

作品数:220被引量:881H指数:14
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相关作者:曹晓建王晓民黄学才徐蔚江基尧更多>>
相关机构:江苏省人民医院首都医科大学丽水市中心医院昆明医学院第二附属医院更多>>
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相关基金:国家自然科学基金国家重点基础研究发展计划国家高技术研究发展计划北京市自然科学基金更多>>
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Nerve growth factor/angiogenin gene activated dermal bioscaffold for nerve repair in cutaneous wound healing
《Nano Research》2025年第3期386-400,共15页Min Yang Fang He Chenghao Cai Yiran Wang Jiaming Shao Wei Zhang Ximing Zhu Tingting Weng Ronghua Jin Tao Shen Chunmao Han Pan Wu Bin Yao Yuqi Zhang Xingang Wang 
supported by grants from the National Key R&D Program of China(Nos.2022YFC2403100 and 2022YFC2403104);the National Natural Science Foundation of China(Nos.81801911,82172198,and 82202443).
Patients with extensive and deep skin defects treated with dermal scaffolds usually emphasize the importance of rapid angiogenesis,while overlook the crucial role of skin nerves in regenerative repair.Insufficient ear...
关键词:cutaneous nerve repair nerve growth factor(NGF) dermal scaffolds angiogenin(ANG) neurological function restoration 
Electroacupuncture alleviates zymosan-induced colorectal hypersensitivity
《Journal of Traditional Chinese Medicine》2025年第1期32-38,共7页LI Siting WANG Shaojun YIN Yehui DE Gejing LI Caicai WANG Ziyan CAO Wenjie 
the National Natural Science Foundation of China(No.81373724,Transient Potential Vanilloid Receptor1 Participates In The Mechanism Of Acupuncture Alleviating Visceral Hypersensitivity);the Joint Innovation Funds of China Academy of Chinese Medical Sciences(No.ZJYB2021-06,Clinical observation of acupuncture in the treatment of chronic urticaria)。
OBJECTIVE:this study to investigate the mechanism underlying the electroacupuncture(EA)alleviates colorectal hypersensitivity,a feature of irritable bowel syndrome(IBS).METHODS:The colorectal hypersensitivity model wa...
关键词:ELECTROACUPUNCTURE colorectal hypersensitivity transient receptor potential channels nerve growth factor substance P protein kinase C gamma 
Acupuncture for overactive bladder in adults:Study protocol for a randomized controlled trial
《Journal of Traditional Chinese Medical Sciences》2024年第4期428-434,共7页Fengqin Cao Diyuan Ma Yueying Chen Qiongqiong Liu Ran Pang 
supported by the National Key Research and Development Program of China(2018YFC2002203);Beijing Science and Technology Program(Z161100000516156);Capital's Funds for Health Improvement and Research(2022-1-6011);Grant from Guang'anmen Hospital,China Academy of Chinese Medical Sciences(2019s443).
Background:Overactive bladder(OAB)is a prevalent condition that substantially degrades patient quality of life.Acupuncture is recognized as an effective therapeutic approach for various urological diseases.However,the...
关键词:Overactive bladder ACUPUNCTURE Randomized controlled trial Nerve growth factor Brain-derived neurotrophic factor Monocyte chemoattractant protein-1 
Chitosan-based thermosensitive hydrogel with long-term release of murine nerve growth factor for neurotrophic keratopathy
《Neural Regeneration Research》2024年第3期680-686,共7页Jie Wu Yulei Huang Hanrui Yu Kaixiu Li Shifeng Zhang Guoqing Qiao Xiao Liu Hongmei Duan Yifei Huang Kwok-Fai So Zhaoyang Yang Xiaoguang Li Liqiang Wang 
supported by PLA General Hospital Program,No.LB20201A010024(to LW).
Neurotrophic keratopathy is a persistent defect of the corneal epithelium,with or without stromal ulceration,due to corneal nerve deficiency caused by a variety of etiologies.The treatment options for neurotrophic ker...
关键词:chitosan corneal reinnervation murine nerve growth factor neurotrophic keratopathy thermosensitive hydrogel 
Effect of electroacupuncture at Neiguan(PC6)at different time points on myocardial ischemia reperfusion arrhythmia in rats被引量:1
《Journal of Traditional Chinese Medicine》2024年第1期113-121,共9页SUN Qianhui CHENG Kai DAI Xingye YANG Zhiwen WU Xiaoling XU Chang QIU Xinghua GAO Xiaofeng LIU Daonan YANG Qirui 
Transversal Project:Scenario-based Application of Wearable Devices for the Treatment of Cardiac Arrhythmias with Superficial Stimulation at the Neiguan(PC6)Point Research(BUCM-2022-JS-FW-003)。
OBJECTIVE:To observe the effects of electroacupuncture at Neiguan(PC6)at different time points on reperfusion arrhythmia(RA)after myocardial ischemia and reperfusion in rats,and to investigate the correlation of this ...
关键词:myocardial reperfusion injury reperfusion arrhythmia ELECTROACUPUNCTURE point PC6(Neiguan) nerve growth factor protein-tyrosine kinases NOREPINEPHRINE 
A new peptide,VD11,promotes structural and functional recovery after spinal cord injury
《Neural Regeneration Research》2023年第10期2260-2267,共8页Shan-Shan Li Bai-Yu Zhang Sai-Ge Yin Zi-Qi Wei Nai-Xin Liu Yi-Lin Li Si-Yu Wang Yu-Heng Shi Jian Zhao Li-Juan Wang Yue Zhang Jun Sun Ying Wang Xin-Wang Yang 
supported by the National Natural Science Foundation of China,Nos.32060212(to YW),81760648(to XWY),81560118(to BYZ);Project of Yunnan Applied Basic Research Project-Kunming Medical University Union Foundation,Nos.202101AY070001-006(to XWY)and 2018FE001(-161)(to JS);Yunnan Applied Basic Research Project Foundation,No.2019FB128(to YW);Project of Yunnan Province Clinical Research Centerfor Chronic Kidney Disease,No.202102AA10060(to BYZ);a grant from Scientific Research Foundation of Department of Education of Yunnan Province,No.2021J0205(to SSL)。
The regenerative capacity of the central nervous system is very limited and few effective treatments are currently available for spinal cord injury.It is therefore a priority to develop new drugs that can promote stru...
关键词:Akt signaling pathway amphibian-derived bioactive peptide AMPK signaling pathway axonal regeneration brain-derived neurotrophic factor ischemia/reperfusion injury motor function nerve growth factor neuroprotective effect spinal cord injury 
Effect of Murine Nerve Growth Factor and Sodium Ganglioside on the Levels of NF-kB p56,TLR-4 and MyD88 in Hippocampus of Epileptic Rats
《Chinese Journal of Biomedical Engineering(English Edition)》2023年第3期124-130,共7页RAO Zhi-hui LIANG Hai-ying XIANG Yan-chun 
Objective:Epilepsy is a prevalent neurological condition,and NF-kB,TLR-4,and MyD88 are significant contributors to its development.Murine nerve growth factor(NGF)and monosialotetrahexosylganlioside sodium for injectio...
关键词:murine nerve growth factor(NGF) ganglioside sodium epilepsy hippocampal tissue neurons 
Qinghua decoction(清化饮)improves chronic nonbacterial prostatitis possibly via regulating the chromogranin A/nerve growth factor/tyrosine kinase A signaling pathway mediated by inflammatory factors被引量:1
《Journal of Traditional Chinese Medicine》2023年第4期695-703,共9页HAN Yunpeng YU Wentao ZHANG Ying XU Huazhou DENG Guoxing FANG Chaoyi 
Hebei Administration of Traditional Chinese Medicine Project:Study on the Neuroendocrine Mechanism of Chronic Prostatitis Rats Regulated by the Method of Clearing heat and Dampness,Activating Blood and Removing Stasis(No.2019087);Hebei Provincial Department of Education for Postgraduate Innovation Ability Training Project:the Mechanism of Improving Pulmonary Function of COPD Rats with Lung Qi Deficiency by Regulating Intestinal Bacteria with Peitu Shengjin Formula(No.CXZZBS2020151);Provincial Universities Basic Research Funds Special Project:Study on the Mechanism of Shenling Baizhu Powder Based on Lung Intestine Axis to Interfere with the Deficiency of Lung and Spleen in Experimental COPD(YJZ2019010)。
OBJECTIVE:To explore the mechanism by which Qinghua decoction(清化饮)regulates neuroendocrine inflammation in chronic nonbacterial prostatitis(CNP)model rats and provide an experimental basis for clinical treatment.ME...
关键词:inflammation INTERLEUKINS chromogranin A nerve growth factor chronic nonbacterial prostatitis Qinghua decoction 
Neurotrophic factor-based pharmacological approaches in neurological disorders被引量:3
《Neural Regeneration Research》2023年第6期1220-1228,共9页Margherita Alfonsetti Michele d’Angelo Vanessa Castelli 
Aging is a physiological event dependent on multiple pathways that are linked to lifespan and processes leading to cognitive decline.This process represents the major risk factor for aging-related diseases such as Alz...
关键词:Alzheimer’s disease brain brain-derived neurotrophic factor glial cell-derived neurotrophic factor nerve growth factor NEUROTROPHINS NEURTURIN Parkinson’s disease stroke tropomyosin receptor kinase receptors 
Artificial nerve graft constructed by coculture of activated Schwann cells and human hair keratin for repair of peripheral nerve defects被引量:1
《Neural Regeneration Research》2023年第5期1118-1123,共6页Han-Jun Qin Hang Li Jun-Ze Chen Kai-Rui Zhang Xing-Qi Zhao Jian-Qiang Qin Bin Yu Jun Yang 
supported by Military Medical Science&Technology Youth Training Program,No. 19QNP005;President Foundation of Nanfang Hospital,Southern Medical University,No. 2020B028 (both to JY)。
Studies have shown that human hair keratin(HHK) has no antigenicity and excellent mechanical properties. Schwann cells, as unique glial cells in the peripheral nervous system, can be induced by interleukin-1β to secr...
关键词:artificial nerve graft bioactive human hair keratin INTERLEUKIN-1Β MACROPHAGES nerve graft nerve growth factor nerve repair peripheral nervous injury Schwann cells 
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