NEUROTROPHINS

作品数:36被引量:114H指数:6
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相关领域:医药卫生生物学更多>>
相关作者:尤元刚更多>>
相关机构:北京协和医学院浙江大学医学院附属第二医院更多>>
相关期刊:《Journal of Hainan Medical University》《Neuroscience Bulletin》《Neuroscience & Medicine》《Journal of Modern Physics》更多>>
相关基金:国家自然科学基金天津市自然科学基金中国博士后科学基金更多>>
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Role of neurogenic inflammation in intervertebral disc degeneration
《World Journal of Orthopedics》2025年第1期24-39,共16页Bao-Gan Peng Yong-Chao Li Liang Yang 
In healthy intervertebral discs(IVDs),nerves and blood vessels are present only in the outer annulus fibrosus,while in degenerative IVDs,a large amount of nerve and blood vessel tissue grows inward.Evidence supports t...
关键词:Intervertebral disc degeneration Discogenic low back pain Neurogenic inflammation NEUROPEPTIDES NEUROTROPHINS Transient receptor potential channels 
Neurotrophins and neural stem cells in posttraumatic brain injury repair被引量:1
《Animal Models and Experimental Medicine》2024年第1期12-23,共12页Wenwen Guo Ke Liu Yinghua Wang Xu Ge Yifan Ma Jing Qin Caiqin Zhang Ya Zhao Changhong Shi 
Laboratory Animal Foundation Program of Military,Grant/Award Number:SYDW[2018]01;Promotion Plan of the Air Force Medical University,Grant/Award Number:2020SWAQ11;Shaanxi Province Innovation Capability Support Plan,Grant/Award Number:2021PT-037。
Traumatic brain injury(TBI)is the main cause of disability,mental health disorder,and even death,with its incidence and social costs rising steadily.Although different treatment strategies have been developed and test...
关键词:mutual effect neural stem cells neurological function NEUROTROPHINS traumatic brain injury 
Nanotechnology-based gene therapy as a credible tool in the treatment of Alzheimer’s disease被引量:5
《Neural Regeneration Research》2023年第10期2127-2133,共7页Aziz Unnisa Nigel H.Greig Mohammad Amjad Kamal 
supported by the Intramural Research Program National Institute on Aginq,NIH。
Toxic aggregated amyloid-βaccumulation is a key pathogenic event in Alzheimer’s disease.Treatment approaches have focused on the suppression,deferral,or dispersion of amyloid-βfibers and plaques.Gene therapy has ev...
关键词:Alzheimer’s disease amyloid-β BACE1 gene silencing gene therapy nanoparticle NEUROTROPHINS small interfering ribonucleic acid 
Neurotrophic factor-based pharmacological approaches in neurological disorders被引量:3
《Neural Regeneration Research》2023年第6期1220-1228,共9页Margherita Alfonsetti Michele d’Angelo Vanessa Castelli 
Aging is a physiological event dependent on multiple pathways that are linked to lifespan and processes leading to cognitive decline.This process represents the major risk factor for aging-related diseases such as Alz...
关键词:Alzheimer’s disease brain brain-derived neurotrophic factor glial cell-derived neurotrophic factor nerve growth factor NEUROTROPHINS NEURTURIN Parkinson’s disease stroke tropomyosin receptor kinase receptors 
Neurotrophic fragments as therapeutic alternatives to ameliorate brain aging被引量:3
《Neural Regeneration Research》2023年第1期51-56,共6页Itzel Ortiz Flores Samuel Treviño Alfonso Díaz 
Aging is a global phenomenon and a complex biological process of all living beings that introduces various changes.During this physiological process,the brain is the most affected organ due to changes in its structura...
关键词:Alzheimer’s disease brain cerebral cortex cognitive function dendritic spines HC-TeTx HIPPOCAMPUS NEURODEGENERATION neuronal survival NEUROTROPHINS 
Towards a comprehensive understanding of p75 neurotrophin receptor functions and interactions in the brain被引量:4
《Neural Regeneration Research》2022年第4期701-704,共4页Joel F.Ritala Seán BLyne Antti Sajanti Romuald Girard Janne Koskimäki 
The role of neurotrophins in neuronal plasticity has recently become a strong focus in neuroregeneration research field to elucidate the biological mechanisms by which these molecules modulate synapses,modify the resp...
关键词:BIOINFORMATICS brain injury data mining NEURON NEUROTROPHINS p75^(NTR) PLASTICITY REGENERATION 
The gut microbiome:implications for neurogenesis and neurological diseases被引量:6
《Neural Regeneration Research》2022年第1期53-58,共6页Cheng Liu Shang-Yu Yang Long Wang Fang Zhou 
There is an increasing recognition of the strong links between the gut microbiome and the brain,and there is persuasive evidence that the gut microbiome plays a role in a variety of physiological processes in the cent...
关键词:gut microbiota microbial-derived metabolites microbiota-gut-brain axis NEUROGENESIS NEUROINFLAMMATION neurological diseases NEUROTROPHINS PROBIOTICS 
Persistent Post-Operative Low Back Pain, True Radiculopathy and Pseudoradiculopathy: Retrospective Observational Study and Point of View of a Practicing Clinician
《Open Journal of Orthopedics》2021年第10期289-300,共12页Reynaldo P. Lazaro 
Purpose: Persistent Postoperative Low Back Pain (PLBP) i...
关键词:RADICULOPATHY Complex Regional Pain Low Back Pain Sinuvertebral Nerve Cytokines NEUROTROPHINS 
Cellular and molecular mechanisms of perineural invasion of pancreatic ductal adenocarcinoma被引量:10
《Cancer Communications》2021年第8期642-660,共19页Jingbo Li Rui Kang Daolin Tang 
Pancreatic ductal adenocarcinoma(PDAC)is an aggressive malignant disease with a unique tumor microenvironment surrounded by an interlaced network of cancer and noncancerous cells.Recent works have revealed that the dy...
关键词:NEUROTROPHINS pancreatic ductal adenocarcinoma perineural invasion schwann cells tumor microenvironment 
Association of neonatal blood levels of brain-derived neurotrophic factor with development of autism spectrum disorder:a systematic review and meta-analysis被引量:1
《World Journal of Pediatrics》2021年第2期164-170,共7页Ya-Kun Liu Hua Gao Shao-Bin Jin Wen-Jun Tu Ya-Jun Chen 
This study was supported by grants from CAMS Innovation Fund for Medical Science(Nos.2017-I2M-1-016 and 2019-I2M-2-006);Natural Science Foundation of Tianjin(No.19JCYBJC26600);China Postdoctoral Science Foundation(Nos.2019M660921 and 2020T130436);Science Foundation for Post Doctorate Research of the Beijing(Nos.2017-ZZ-123 and 2020-ZZ-005);Youth Backbone Project from Chinese Academy of Medical Science Institute of Radiation Medicine(No.2019043).
Background Our goal was to evaluate the association between neonatal blood brain-derived neurotrophic factor(BDNF)level and autism spectrum disorder(ASD)diagnosis later in life.Methods MEDLINE and Web of Science datab...
关键词:Autism spectrum disorder Autistic disorder Brain-derived neurotrophic factor NEONATES NEUROTROPHINS 
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