NEURAL_STEM_CELL

作品数：153被引量：663H指数：13
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相关机构：复旦大学复旦大学上海医学院上海交通大学医学院附属第三人民医院广州中医药大学更多>>
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Quiescent Adult Neural Stem Cells:Developmental Origin and Regulatory Mechanisms
《Neuroscience Bulletin》2024年第9期1353-1363,共11页Han Meng Yu Huan Kun Zhang Xuyang Yi Xinyu Meng Enming Kang Shengxi Wu Wenbing Deng Yazhou Wang 
National Natural Science Foundation of China(31970907 and 82171346).
The existence of neural stem cells(NSCs)in the adult mammalian nervous system,although small in number and restricted to the sub-ventricular zone of the lateral ventricles,the dentate gyrus of the hippocampus,and the ...
关键词：Quiescent Neural stem cell Neuronal regeneration INJURY 
Neural Stem Cell Competition
《Neuroscience Bulletin》2024年第2期277-279,共3页Yanan Li Jie He 
Cell competition is an adaptive surveillance mechanism to ensure the robustness of developmental outputs,maintain tissue integrity,and regulate tumor progression in multicellular organisms,which is highly conserved fr...
关键词：thereby MAINTAIN eliminating 
The Orphan Nuclear Receptor TLX/NR2E1 in Neural Stem Cells and Diseases
《Neuroscience Bulletin》2016年第1期108-114,共7页Tao Wang Jian-Qiong Xiong 
The human TLX gene encodes an orphan nuclear receptor predominantly expressed in the central nervous system. Tailess and Tlx, the TLX homologues in Drosophila and mouse, play essential roles in body-pattern formation ...
关键词：TLX Neural stem cell NEUROGENESIS 
Induced neural stem/precursor cells for fundamental studies and potential application in neurodegenerative diseases被引量：1
《Neuroscience Bulletin》2015年第5期589-600,共12页Ting Shen Jiali Pu Tingting Zheng Baorong Zhang 
supported by the National Natural Science Foundation of China (81271248 and 81400933)
Recent research has shown that defined sets of exogenous factors are sufficient to convert rodent and human somatic cells directly into induced neural stem cells or neural precursor cells（iNSCs/iNPCs）.The process of...
关键词：induced neural stem cell induced neural precursor cell transdifferentiation fundamental study clinical application neurodegenerative disease 
Activity-dependent signaling mechanisms regulating adult hippocampal neural stem cells and their progeny被引量：7
《Neuroscience Bulletin》2014年第4期542-556,共15页Andrew J.Crowther Juan Song 
supported by startup funds from the Department of Pharmacology at the University of North Carolina (UNC);grants from NARSAD,the Whitehall Foundation;the American Heart Association and a UNC Biological and Biomedical Sciences Program training grant;an NIH T32 Neurobiology Curriculum training grant
Adult neural stem cells （NSCs） reside in a restricted microenvironment, where their development is controlled by subtle and presently underexplored cues. This raises a significant question： what instructions must b...
关键词：neural stem cell neuronal development neuronal plasticity 
Glial cells in neuronal development:recent advances and insights from Drosophila melanogaster被引量：3
《Neuroscience Bulletin》2014年第4期584-594,共11页Jiayao Ou Yijing He Xi Xiao Tian-Ming Yu Changyan Chen Zongbao Gao Margaret S.Ho 
supported by grants from the National Basic Research Program of China (973 Program 2010CB944900 and 2013CB945602);the National Natural Science Foundation of China (31270825 and 31171043);Fundamental Research Funds for the Central Universities We thank members of the Ho lab for discussion and comments
Gila outnumber neurons and are the most abundant cell type in the nervous system. Whereas neurons are the major carriers, transducers, and processors of information, glial cells, once considered mainly to play a passi...
关键词：GLIA neuronal development GCM NEURODEGENERATION neural stem cell synapse formation axon pruning 
Epigenetics and neural stem cell commitment被引量：1
《Neuroscience Bulletin》2007年第4期241-248,共8页汤海亮 朱剑虹 
Neural stem cell is presently the research hotspot in neuroscience. Recent progress indicates that epigenetic modulation is closely related to the self-renewal and differentiation of neural stem cell. Epigenetics refe...
关键词：stem cells EPIGENESIS neuron restrictive silencer element genomic imprinting H19 non-coding RNA 
Repair of spinal cord injury by neural stem cells modified with BDNF gene in rats被引量：13
《Neuroscience Bulletin》2006年第1期34-40,共7页Wei LI Wen-Qin CAI Cheng-Ren LI 
Objective To explore repair of spinal cord injury by neural stem cells （NSCs） modified with brain derived neurotrophic factor （BDNF） gene （BDNF-NSCs） in rats. Methods Neural stem cells modified with BDNF gene we...
关键词：genetic modification neural stem cell spinal cord injury REPAIR 
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