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作品数：394被引量：1163H指数：14
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Activation of glutamine synthetase(GS)as a new strategy for the treatment of major depressive disorder and other GS-related diseases
《Acta Pharmacologica Sinica》2025年第4期880-891,共12页Jae Soon Kang Hwajin Kim Ji Hyeong Baek Miyoung Song Hyeongchan Park Wonjune Jeong Hye Jin Chung Dae Young Yoo Dong Kun Lee Sang Won Park Hyun Joon Kim 
supported by the National Research Foundation(NRF)(Grant numbers NRF-2021R1A5A802949012 and 2022R1A2C100529611);the Commercializations Promotion Agency for R&D Outcomes(COMPA)(Grant number 1711173796)funded by the Ministry of Science and ICT(MSIT)of the Korean government.
Glutamine synthetase(GS)plays a crucial role in the homeostasis of the glutamate–glutamine cycle in the brain.Hypoactive GS causes depressive behaviors.Under chronic stress,GS has no change in expression,but its acti...
关键词：depression glutamine synthetase tyrosine nitration tyrosine-containing dipeptide EPILEPSY HYPERAMMONEMIA 
Role of transient elastography in the diagnosis and prognosis of Fontan-associated liver disease
《World Journal of Gastroenterology》2025年第11期74-87,共14页Marta Cuadros Marta Abadía Pilar Castillo María Dolores Martín-Arranz Nerea Gonzalo Miriam Romero Araceli García-Sánchez Javier García-Samaniego Antonio Olveira JoséRuiz-Cantador Óscar González-Fernández Inés Ponz Pablo Merás Carlos Merino Adriana Rodríguez-Chaverri Enrique Balbacid Consuelo Froilán 
BACKGROUND Fontan-associated liver disease(FALD)often occurs in patients with single-ventricle physiology following Fontan surgery,and ranges from liver congestion to cirrhosis.The assessment of the severity of FALD u...
关键词：Transient elastography Liver stiffness Fontan-associated liver disease FONTAN Congenital heart disease Single ventricle 
Mercury contents and potential exposure risk of rice-containing food products
《Journal of Environmental Sciences》2025年第2期683-690,共8页Xin Wang Yingjun Wang Yaqi Zhang Ziyan Liu Xiaomeng Ji Yong Cai 
supported by the Shandong Provincial Natural Science Foundation (No.ZR2022QB242);the National Natural Science Foundation of China (No.22306111 and 22306108);the Shandong Provincial Natural Science Foundation (No.ZR2020ZD20);the Chinese Postdoctoral Science Foundation (No.2023M732059).
Mercury(Hg),especially methylmercury(MeHg),accumulation in rice grain due to rice paddy possessing conditions conducive to Hg methylation has led to human Hg exposure through consumption of rice-based daily meals.In a...
关键词：MERCURY METHYLMERCURY Processed food products RICE Dietary exposure 
Robot assisted anatomical liver resection is safe for patient with hepatocellular carcinoma underlying Fontan-associated liver disease
《Hepatobiliary & Pancreatic Diseases International》2025年第1期111-113,共3页O˘guzhan¸S al Katsunori Sakamoto Kei Tamura Masahiko Honjo Yusuke Nishi Naotake Funamizu Kohei Ogawa Yasutsugu Takada 
Fontan operation is indicated in a single ventricle congenital heart disease which creates a shunt between superior vena cava and pulmonary arteries leading to increased pressure in central venous system and congestiv...
关键词：FONTAN HEPATOCELLULAR liver 
Assessment of leachate-contaminated clays using experimental and artificial methods
《Journal of Rock Mechanics and Geotechnical Engineering》2025年第1期524-538,共15页Hossein Moradi Moghaddam Ahmad Fahimifar Taghi Ebadi Mohsen Keramati Sumi Siddiqua 
The investigation of leachate-contaminated clay(LCC)is essential for landfill engineering assessment and achievement of sustainable development goals.Several static and dynamic laboratory tests,including unconfined co...
关键词：Contaminated liner Dynamic parameter Response surface methodology(RSM) Python method 
Research progress on piperidine-containing compounds as agrochemicals
《Chinese Chemical Letters》2025年第1期58-67,共10页Wei Sun Anjing Liao Li Lei Xu Tang Ya Wang Jian Wu 
financial support from the National Natural Science Foundation of China(No.32072445);the Science and Technology Plan Project of Guizhou Province(Qiankehezhicheng[2024]the general 083);the Program of Introducing Talents to Chinese Universities(No.D20023);the Central Government Guides Local Science and Technology Development Fund Projects(Qiankehezhongyindi(2023)001);the Technology Achievement Transformation(general project)of Guizhou Province(Qiankehechengguo[2022]the general 063);Key Agricultural Technology R&D Projects of the Xinjiang Production and Construction Corps(NYHXGG,No.2023AA602);the Frontiers Science Centre for Asymmetric Synthesis and Medicinal Molecules;Department of Education;Guizhou Province[Qianjiaohe KY(2020)004];the specific research fund of TheInnovation Platform for Academicians of Hainan Province(No.SQ2020PTZ0009)。
Piperidine is a crucial pharmacophore and a special scaffold in the realm of drug discovery.Its flexibility increases the molecule’s capability to bind to the receptor.The piperidine-containing compounds are distingu...
关键词：PIPERIDINE Agrochemicals Biological activity Structure-activity relationships Mechanism of action 
High-Performance Edge-Contact Monolayer Molybdenum Disulfide Transistors
《Research》2024年第4期119-126,共8页Jiankun Xiao Xiong Xiong Xinhang Shi Shiyuan Liu Shenwu Zhu Yue Zhang Ru Huang Yanqing Wu 
supported by the Natural Science Foundation of China(grant nos.92364203,92464303,62090034,62425402,and 62104012);the National Key Research and Development Program of China(grant nos.2022YFB4400100 and 2021YFA1202903);Beijing Natural Science Foundation(grant no.4242057);Technology Innovation Program of Hunan Province(grant no.2021RC5008).
Edge contact is essential for achieving the ultimate device pitch scaling of stacked nanosheet transistors with monolayer 2-dimensional(2D)channels.However,due to large edge-contact resistance between 2D channels and ...
关键词：SULFIDE utilizing MOLYBDENUM 
Pyrimidine-containing covalent organic frameworks for efficient photosynthesis of hydrogen peroxide via one-step two electron oxygen reduction process
《Nano Research》2024年第11期9498-9506,共9页Hongyu Chen Hao Zhang Kai Chi Yan Zhao 
financially supported by the Nation Key Research and Development(R&D)Program of China(No.2022YFB3603804);Natural Science Foundation of Shanghai(No.22ZR1407800).
The photocatalytic oxygen reduction reaction (ORR), particularly the one-step two-electron (2e−) pathway, is a highly promising strategy for efficient and selective hydrogen peroxide (H_(2)O_(2)) synthesis. However, c...
关键词：covalent organic frameworks photocatalysis hydrogen peroxide oxygen reduction reaction pyrimidine units 
High-performance imidazole-containing polymers for applications in high temperature polymer electrolyte membrane fuel cells被引量：1
《Journal of Energy Chemistry》2024年第11期512-523,共12页Tong Mu Lele Wang Qian Wang Yang Wu Patric Jannasch Jingshuai Yang 
Natural Science Foundation of China (51603031);Liaoning Provincial Natural Science Foundation of China (2020-MS-087);China Scholarship Council(202306080157)。
This work focuses on the development of high temperature polymer electrolyte membranes(HT-PEMs)as key materials for HT-PEM fuel cells(HT-PEMFCs).Recognizing the challenges associated with the phosphoric acid(PA) doped...
关键词：High temperature polymer electrolyte membrane Imidazole-containing polymer Chemical stability Fuel cell 
钢结构加固技术及含裂纹构件安全评估方法
《中国金属通报》2024年第22期149-151,共3页沈莲冰 
针对国内某铜矿主厂房钢结构老化及裂纹问题,探讨钢结构加固技术及含裂纹构件的安全评估方法。通过综述增大截面焊接、粘贴钢板、粘贴纤维增强复合材料、组合加固和预应力加固等五种主要加固技术,分析各自的特点、适用范围及施工要点。...
关键词：钢结构加固 裂纹构件 安全评估 断裂力学 SINTAP-FAD 加固策略 
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