PHARM

作品数：181被引量：376H指数：11
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A new strategy for pharmacodynamic substance screening and research on gut microbiota pathway mechanisms based on UPLC-Q-orbitrap-MS and 16S rRNA
《Journal of Traditional Chinese Medical Sciences》2025年第1期56-70,共15页Zhiying Yu Tong Li Jie Yang Jianghua He Weijiang Zhang Siyuan Li Yunpeng Qi Yihui Yin Ling Dong Wenjuan Xu 
supported by Fundamental Research Funds for the Central Universities(2022-ZXFZJJ-028).
Objective:To establish a progressive research strategy for“colonic components analysis-efficacy verification and mechanism exploration-gut microbiota”,screen pharmacodynamic substances,and investigate their mechanis...
关键词：COLON Gegen Qinlian decoction Gut microbiota Mechanism research Pharmacodynamic component screening TCM-gut microbiota interaction Ulcerative colitis 
Author correction to“Generation ofαGal-enhanced bifunctional tumor vaccine”[Acta Pharm Sin B 12(2022)3177-3186]
《Acta Pharmaceutica Sinica B》2025年第2期1207-1207,共1页Jian He Yu Huo Zhikun Zhang Yiqun Luo Xiuli Liu Qiaoying Chen Pan Wu Wei Shi Tao Wu Chao Tang Huixue Wang Lan Li Xiyu Liu Yong Huang Yongxiang Zhao Lu Gan Bing Wang Liping Zhong 
The authors regret Fig.5C in the published article contained an incorrect image.Specifically,the image for the MHCC97H(pLVX-Puro)/DC group was mistakenly used during copying and pasting in the process of assembling th...
关键词：generation figure correction copying pasting bifunctional tumor vaccine mhcc h plvx puro dc group original data access GAL 
Author correction to“The novel ER stress inducer Sec C triggers apoptosis by sulfating ER cysteine residues and degrading YAP via ER stress in pancreatic cancer cells”[Acta Pharm Sin B 12(2022)210-227]
《Acta Pharmaceutica Sinica B》2025年第2期1208-1209,共2页Junxia Wang Minghua Chen Mengyan Wang Wenxia Zhao Conghui Zhang Xiujun Liu Meilian Cai Yuhan Qiu Tianshu Zhang Huimin Zhou Wuli Zhao Shuyi Si Rongguang Shao 
The authors regret that there was an error in the use of GAPDH image in PANC-1 cells of Fig.5B due to mistakenly pasting in the process of assembling figures.The wrong data are replaced by right ones of the same batch...
关键词：mistakenly pasting assembling figuresthe er stress yap APOPTOSIS wrong data gapdh image pancreatic cancer 
Vedolizumab serum trough concentrations with and without thiopurines in ulcerative colitis: The prospective VIEWS pharmacokinetics study
《World Journal of Gastroenterology》2025年第2期102-112,共11页Thanaboon Chaemsupaphan Aviv Pudipeddi Hui-Yu Lin Sudarshan Paramsothy Viraj C Kariyawasam Melissa Kermeen Rupert W Leong 
Supported by Takeda Australia,No.IISR-2016-101883.
BACKGROUND Ulcerative colitis(UC)is a chronic inflammatory condition requiring continuous treatment and monitoring.There is limited pharmacokinetic data on vedolizumab during maintenance therapy and the effect of thio...
关键词：PHARMACOKINETIC Vedolizumab THIOPURINE Ulcerative colitis Trough concentration Antibody Inflammatory bowel diseases 
Protocol of clinical population pharmacokinetics/pharmacodynamics analysis of alkaloids from the leaves of Alstonia scholaris in acute bronchitis patients
《Guideline and Standard in Chinese Medicine》2024年第4期236-242,共7页Chunying He Weiyi Cao Wantong Zhang Yunli Zhao Xiaodong Luo Rui Li 
supported by the National Science of China Academy of Chinese Medical Sciences(No.zz0908022);the National Natural Science Foundation of China(81603505);the National Science and Technology major project(2017ZX09304003);the National Key Research and Development Program(2018YFC1706006).
Objective:To validate whether orally administered capsules of alkaloids from the leaves of Alstonia scholaris(CALAS)can improve the clinical indices of acute bronchitis and to investigate the alterations in the relati...
关键词：acute tracheobronchitis dengtaiye capsules PHARMACOKINETICS/PHARMACODYNAMICS population 
Integrins and NAFLD-associated liver diseases:clinical associations,pathophysiological mechanisms and pharmacological implications
《Acta Biochimica et Biophysica Sinica》2024年第11期1573-1583,共11页Yangyue Ni Mengwen Huang Shiyang Chen Shihui Wang Jianfeng Chen 
This work was supported by the grants from the National Key R&D Program of China(Nos.2020YFA0509003 and 2020YFA0509102 to J.C.);the National Natural Science Foundation of China(Nos.31830112,32030024,31900536,32170769 to J.C.,No.32300633 to M.H.,and No.32200642 to S.C.);the Program of Shanghai Academic Research Leader(No.19XD1404200 to J.C.);the China Postdoctoral Science Foundation(No.2023M733487 to M.H.and No.2020M671262 to S.W.);the China Postdoctoral Innovative Talent Support Program(No.BX20190345 to S.W.)。
Nonalcoholic fatty liver disease(NAFLD)is a leading cause of chronic liver disease and poses a substantial health burden with increasing incidence globally.NAFLD encompasses a spectrum extending from hepatic steatosis...
关键词：INTEGRINS NAFLD NASH NAFLD-related HCC diagnostics and treatments 
Erratum to “Phenylalanine deprivation inhibits multiple myeloma progression by perturbing endoplasmic reticulum homeostasis” [Acta Pharm Sin B 14 (2024) 3493-3512]
《Acta Pharmaceutica Sinica B》2024年第11期5088-5088,共1页Longhao Cheng Xiaoxue Wang Aijun Liu Ying Zhu Hu Cheng Jiangling Yu Lili Gong Honglin Liu Guolin Shen Lihong Liu 
The publisher regrets that one Supporting Information is missed during publication.The publisher would like to apologise for any inconvenience caused.
关键词：HOMEOSTASIS DEPRIVATION 
Author correction to “Identification of anthelmintic parbendazole as a therapeutic molecule for HNSCC through connectivity map-based drug repositioning” [Acta Pharm Sin B 12 (2022) 2429-2442]
《Acta Pharmaceutica Sinica B》2024年第11期5089-5090,共2页Dong Liang Chen Yu Zhao Ma Xingye Yang Zhenzhen Li Xuhui Dong Xiaojun Qin Lupei Du Minyong Li 
The authors regret that a mistake occurred during the presentation of Fig.5A,in which the result of 0.1μmol/L CA-4 group appeared incorrectly when merging different imaging pictures into one.This correction does not ...
关键词：CORRECTION finding CONNECTIVITY 
A Study of Pharmacist-Patient Communication: Examining Optimal Distance and Angle Using an Eye-Tracking System
《Pharmacology & Pharmacy》2024年第10期315-326,共12页Chika Nakayama Saori Gocho Yukina Miyagi Yuka Miyachi Taeyuki Oshima 
This study focuses on seating arrangement and interpersonal distance as important aspects of nonverbal communication and aims to elucidate the optimal distance and angle between pharmacist and patient through an analy...
关键词：Eye-Tracking System Nonverbal Communication Pharmacist Medication Instruction Eye Movements 
Author correction to“Gas-propelled nanomotors alleviate colitis through the regulation of intestinal immunoenvironmenthematopexis-microbiota circuits”[Acta Pharm Sin B 14(2024)2732-2747]
《Acta Pharmaceutica Sinica B》2024年第9期4193-4193,共1页Bo Xiao Yuqi Liang Ga Liu Lingshuang Wang Zhan Zhang Libin Qiu Haiting Xu Sean Carr Xiaoxiao Shi Rui LReis Subhas CKundu Zhenhua Zhu 
The authors regret that there are errors in the author information and author contributions.The name of the corresponding author,Zhenghua Zhu,should be corrected to Zhenhua Zhu.The modification does not affect the res...
关键词：journal CORRECTION contributions 
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