PROSTATE

作品数：798被引量：1736H指数：18
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相关机构：北京大学第一医院四川大学华西医院浙江大学医学院附属第一医院首都医科大学更多>>
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相关基金：国家自然科学基金国家重点基础研究发展计划广东省自然科学基金中国博士后科学基金更多>>
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Recent advances in tissue stem cells被引量：4
《Science China(Life Sciences)》2021年第12期1998-2029,共32页Xin Fu Qiang He Yu Tao Mengdi Wang Wei Wang Yalong Wang Qing Cissy Yu Fang Zhang Xiaoyu Zhang Ye-Guang Chen Dong Gao Ping Hu Lijian Hui Xiaoqun Wang Yi Arial Zeng 
supported by grants from the National Natural Science Foundation of China(31988101 and 31730056 to YGC;32125013 and 81772723 to DG;32170804 to PH;31930030 to LH;91732301,31671072,31771140,81891001,91432111,81527901,31400977,31625013 to XW;31625020,31830056,31861163006 to YAZ);the Ministry of Science and Technology of China(2017YFA0103601 to YGC;2020YFA0509000,2017YFA0505500 to DG;2017YFA0102700 to PH;2019YFA0802001,2019YFA0801503 to LH;2017YFA0102601,2019YFA0110100 to XW;2020YFA0509002,2019YFA0802002 to YAZ);the Strategic Priority Research Program of the Chinese Academy of Science(XDA16020400 to PH;XDA16020200 to YAZ);the Shanghai Science and Technology Commission(21XD1424200,21ZR1470100 to DG);the Basic Frontier Science Research Program of Chinese Academy of Sciences(ZDBS-LY-SM015 to DG);Space Medical Experiment Project of China Manned Space Program(HYZHXM01017 to PH);the Grants of Beijing Brain Initiative of Beijing Municipal Science&Technology Commission(Z181100001518004 to XW)。
Stem cells are undifferentiated cells capable of self-renewal and differentiation,giving rise to specialized functional cells.Stem cells are of pivotal importance for organ and tissue development,homeostasis,and injur...
关键词：neural stem cells muscle stem cells liver progenitors pancreatic islet stem/progenitor cells intestinal stem cells prostate stem cells 
New advances in immunotherapy for prostate cancer
《Life Research》2019年第4期152-159,共8页Hassan Lois Bala 
In recent years, prostate cancer has been known to have an increasing incidence worldwide. In 2012, prostate cancer was recognized as the second most frequent cancer to occur in men and fifth leading cause of cancer m...
关键词：PROSTATE cancer IMMUNOTHERAPY CAR T-CELL THERAPY 
Forkhead domain mutations in FOXA1 drive prostate cancer progression被引量：3
《Cell Research》2019年第9期770-772,共3页Shuai Gao Sujun Chen Dong Han David Barrett Wanting Han Musaddeque Ahmed Susan Patalano Jill A. Macoska Housheng Hansen He Changmeng Cai 
Dear Editor,F0XA1 (Forkhead Box Protein A1)is a pioneer transcription factor (TF) that functions to loosen the compact chromatin structure to facilitate binding of other TFs such as estrogen receptor and androgen rece...
关键词：FOXA1 CASTRATION-RESISTANT Pca (CRPC) PROSTATE cancer (Pca) 
Neuroendocrine prostate carcinoma cells originate from the p63-expressing basal cells but not the pre-existing adenocarcinoma cells in mice被引量：3
《Cell Research》2019年第5期420-422,共3页
Dear Editor,The prostate epithelium consists of p63/cytokeratin 14/cytokeratin 5-expressing(p63+/K14+/K5+)basal cells(BCs),K8+/androgen receptor(AR)+luminal epithelial cells(LECs),and neuroendocrine cells(NECs)express...
关键词：NEUROENDOCRINE carcinoma MICE 
Risk of prostate cancer in men with spinal cord n jury： a systematic review and meta-analysis
《Asian Journal of Andrology》2018年第6期555-560,共6页Arcangelo Barbonetti Settimio D'ndrea Alessio Martorella Giorgio Felzani Sandro Francavilla Felice Francavilla 
A lower risk of prostate cancer has been reported in men with spinal cord injury （SCI） as compared to that observed in able-bodied subjects. As injury-related consequences can have opposite effects on prostate patho...
关键词：PARAPLEGIA prostate cancer prostate-specific antigen QUADRIPLEGIA spinal cord injury 
National Comprehensive Cancer Network （NCCN） riSK classification in predicting biochemical recurrence after radical prostatectomy： a retrospective cohort study in Chinese prostate cancer patients被引量：6
《Asian Journal of Andrology》2018年第6期551-554,共4页Hua Xu Yao Zhu Bo Dai Ding-Wei Ye 
This study was sponsored by the National Natural Science Foundation of China （No. 81472377） and the Natural Science Foundation of Shanghai （No. 16ZR1406500）. The authors also thank Wei-Yi Yang, Cui-Zhu Zhang, and Ying Shen for helping with follow-up of patients.
This study aimed to assess the role of the National Comprehensive Cancer Network （NCCN） risk classification in predicting biochemical recurrence （BCR） after radical prostatectomy （RP） in Chinese prostate cancer ...
关键词：biochemical recurrence prostate cancer radical prostatectomy National Comprehensive Cancer Network risk classification 
Elimination of CD4^low HLA-G^＋ T cells overcomes castration- resistance in prostate cancer therapy被引量：4
《Cell Research》2018年第11期1103-1117,共15页Chao Wang Jiahuan Chen Qianfei Zhang Wang Li Shengbo Zhang Yanjie Xu Fang Wang Bing Zhang Yan Zhang Wei-Qiang Gao 
Androgen deprivation therapy （ADT） is a main treatment for prostate cancer （PCa） but the disease often recurs and becomes castration-resistant in nearly all patients. Recent data implicate the involvement of immun...
关键词：HLA-G CD4 治疗学 前列腺 房间 癌症 阉割 CELECOXIB 
Identification and characterization of novel fusion genes in prostate cancer by targeted RNA capture and next-generation sequencing被引量：1
《Acta Biochimica et Biophysica Sinica》2018年第11期1166-1172,共7页Jie Yang Yun Chen Jingxiao Lu Xingxing Wang Lu Wang Jialong Liang Zhong Sheng Sun 
Gene fusions play critical roles in the development and progression of prostate cancer,and have been used as molecular biomarkers for diagnosis of the malignant disease.To further explore the novel fusions in prostate...
关键词：gene fusion PROSTATE cancer ETVI TARGETED RNA CAPTURE next-generation sequencing 
Using the Prostate Imaging Reporting and Data System version 2 （PI-RIDS v2） to detect prostate cancer can prevent unnecessary biopsies and invasive treatment被引量：15
《Asian Journal of Andrology》2018年第5期459-464,共6页Chang Liu Shi-Liang Liu Zhi-Xian Wang Kai Yu Chun-Xiang Feng Zan Ke Liang Wang Xiao-Yong Zeng 
Prostate cancer （PCa） is one of the most common cancers among men globally. The authors aimed to evaluate the ability of the Prostate Imaging Reporting and Data System version 2 （PI-RADS v2） to classify men with P...
关键词：diagnosis multiparametric magnetic resonance imaging prostate cancer Prostate Imaging Reporting and Data Systemversion 2 prostate-specific antigen prostate-specific antigen density 
The transcription factor ZEB1 promotes an aggressive phenotype in prostate cancer cell lines被引量：5
《Asian Journal of Andrology》2018年第3期294-299,共6页Octavio Orellana-Serradell Daniela Herrera Enrique A Castellon Hector R Contreras 
It has been reported that one of the factors that promotes tumoral progression is the abnormal activation of the epithelial-mesenchymal transition program. This process is associated with tumoral cells acquiring invas...
关键词：epithelial-mesenchymal transition prostate cancer transcriptional repression ZEB1 
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