SCHISTOSOMA_JAPONICUM

作品数：111被引量：381H指数：11
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相关机构：南京医科大学中山医科大学中国预防医学科学院广州医科大学更多>>
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Identification and Characterization of Peptides Mimicking the Epitopes of Metalloprotease of Schistosoma Japonicum被引量：2
《Cellular & Molecular Immunology》2005年第3期219-223,共5页Lianfei Tang Yuxiao Chen Linqian Wang Shunke Zhang Xianfang Zeng Xinyuan Yi 
In an attempt to isolate and characterize peptides mimicking epitopes of metalloprotease and explore their immunological protection against Schistosoma japonicum （S. japonicum）, polyclonal anti-metalloprotease sera ...
关键词：phage displayed peptide library EPITOPE Schistosomajaponicum METALLOPROTEASE 
Schistosoma japonicum: construction of phage display antibody library and its application in the immunodiagnosis of infection被引量：5
《Chinese Medical Journal》2004年第11期1697-1703,共7页陈代雄 何蔼 詹希美 俞慕华 雷智刚 孟锦绣 李卓雅 梁瑜 张瑞琳 
ThisworkwassupportedbytheWHOSpecialProgramforResearchandTraininginTropicalDiseases (No 970 978) ,theScienceFoundationfromtheMinistryofHealthofChina (No 98 1 85 ),andtheGuangdongProvincialScienceFoundationfor"2 11"Engineering
Background A monoclonal antibody would be an effective tool for the detection of circulating antigens in the serum of patients with schistosomiasis, but the traditional way of producing monoclonal antibodies is not c...
关键词：phage display antibody library Schistosoma jap onicum single-chain variable fragment   antibody SERODIAGNOSIS 
Isolation and Characterization of 44.6 kDa Protein from Schistosoma japonicum Male Worm
《Journal of Microbiology and Immunology》2004年第2期136-139,共4页陈欲晓 易新元 曾宪芳 袁仕善 张顺科 Larry MCREYNOLDS 
This work was supported by WHO TDR (No.980268)
Soluble male worm antigen of Schistosoma japonicum ( Sj ) was investigated for development of new vaccine candidate. SDS-PAGE and Western blotting were performed to compare the difference between soluble antigens from...
关键词：Schistosoma japonicum Male adult worm ANTIGENICITY 
Schistosoma japonicum: Isolation and Identification of Peptides Mimicking Ferritin Epitopes from Phage Display Library被引量：8
《Acta Biochimica et Biophysica Sinica》2004年第3期206-210,共5页Lian-FeiTANG Xin-YuanYI Xian-FangZENG Lin-QianWANG Shun-KeZHANG 
This work was supported by the grant from WHO/TDR (980268)
In an attempt to isolate and identify the antigenic epitopes on ferritin ofSchistosomajaponicum (SjFer) and to test their protective potentiality against Schistosoma japonicum(S.j),polyclonal antisera against SjFer wa...
关键词：phage displayed peptide library EPITOPE Schistosoma japonicum FERRITIN 
Selection of Immunogenic Peptide Mimics of Male Worm Origin of Schistosoma Japonicum using Phage Display Peptide Library
《Journal of Microbiology and Immunology》2004年第1期66-69,共4页陈欲晓 易新元 曾宪芳 王林纤 唐连飞 章洁 Mcreynolds Larry 
ThisprojectwassupportedbyWHO TDR(No.980268)
To select the immunogenic short peptide mimics of male worm origin of Schistosoma japonicum (Sj) and to explore their protection effect against schistosomiasis in mice, the random phage display peptide library of 12-m...
关键词：Schistosoma japonicum Male worm Short peptide mimic Phage peptide library Screening 
Selection of the Mimic Epitopes of Antigens from Schistosoma japonicum by Using Phage Display Techniques被引量：1
《Journal of Microbiology and Immunology》2003年第1期91-94,共4页王敏 易新元 曾宪芳 李先平 周东明 张顺科 章洁 
This study was supported by grants from WHO/TDR (980255) and the Science Commission of Hunan Province (00jzy2115)
To obtain short peptides simulating antigenic epitopes related to natural resistance against Schistosoma japonicum (S.j) in rats, and to explore their immune protection against S.j in mice, phage random peptide librar...
关键词：Shistosoma japonicum Antigenic peptides IMMUNOSCREENING Phage random peptide library 
Partial protection induced by phage library-selected peptides mimicking epitopes of Schistosoma japonicum被引量：7
《Chinese Medical Journal》2003年第1期138-141,共4页欧阳理 易新元Department of Pathogen Biology 曾宪芳Department of Pathogen Biology 周金春Department of Pathogen Biology 王庆林Department of Pathogen Biology Larry Mc Reynolds 
ThisworkissupportedbygrantsfromMinistryofScienceandTechnologyofChina (No 96 A2 3 0 6 0 4),WHO/TDR (IDNo 980 2 5 5 )andNewEnglandBiolabs,Inc USA
Objective To obtain peptide mimicking epitopes of Schistosoma japonicum (S.japonicum) through screening of a phage peptide library and to test their potential for induction of protection. Methods S.japonicum infect...
关键词：peptide library EPITOPES Schistosoma japonicum 
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