SULFOXIMINE

作品数：14被引量：43H指数：3
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相关领域：医药卫生更多>>
相关作者：张宇孙健更多>>
相关机构：中国科学院成都生物研究所中国科学院研究生院更多>>
相关期刊：《Acta Pharmacologica Sinica》《Science China Chemistry》《World Journal of Gastroenterology》《Advances in Parkinson's Disease》更多>>
相关基金：国家自然科学基金更多>>
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Reversing ferroptosis resistance by MOFs through regulation intracellular redox homeostasis被引量：3
《Asian Journal of Pharmaceutical Sciences》2023年第1期86-96,共11页Chengcheng Wang JiaoWang Xue Pan Shuang Yu Meiqi Chen Yan Gao Zilin Song Haiyang Hu Xiuli Zhao Dawei Chen Fei Han Mingxi Qiao 
As a non-apoptotic cell death form,ferroptosis offers an alternative approach to overcome cancer chemotherapy resistance.However,accumulating evidence indicates cancer cells can develop ferroptosis resistance by evolv...
关键词：Ferroptosis Buthionine-(S R)-sulfoximine GLUTATHIONE Metal organic framework Photodynamic therapy Immunogenic cell death 
Osthole prevents tamoxifen-induced liver injury in mice被引量：7
《Acta Pharmacologica Sinica》2019年第5期608-619,共12页Wen-bo Zhou Xin-xin Zhang Yun Cai Wu Sun Hao Li 
the National Natural Science Foundation of China (No.81270944 and No.81070678).
Tamoxifen (TMX) is an antiestrogen drug that is used in the treatment and prevention of all stages of estrogen-dependent breast cancer. Adverse effects of TMX include hepatotoxicity. In this study, we investigated the...
关键词：hepatotoxicity TAMOXIFEN oxidative stress OSTHOLE MAPK SB203580 L-buthionine SULFOXIMINE N-ACETYL-L-CYSTEINE 
Glutathione depleting drugs, antioxidants and intestinal calcium absorption被引量：7
《World Journal of Gastroenterology》2018年第44期4979-4988,共10页Luciana Moine María Rivoira Gabriela Díaz de Barboza Adriana Pérez Nori Tolosa de Talamoni 
Glutathione （GSH） is a tripeptide that constitutes one of the main intracellular reducing compounds. The normal content of GSH in the intestine is essential to optimize the intestinal Ca2＋ absorption. The use of GS...
关键词：GLUTATHIONE Transcellular and paracellular Ca^2＋pathways DL-buthionine-S R-sulfoximine Fructose rich diet MENADIONE Sodium deoxycholate Glutamine Ursodeoxycholic acid Melatonin Quercetin NARINGIN 
Effect of Alteration of Glutathione Content on Cell Viability in α-Synuclein-Transfected SH-SY5Y Cells
《Advances in Parkinson's Disease》2017年第3期93-100,共8页Ken-Ichi Tanaka Kanako Sonoda Masato Asanuma 
It is well known that α-synuclein (αS) plays an important role in the pathogenesis of Parkinson’s disease (PD). Moreover, oxidative stress is also thought to be an important factor in PD due to induction of dopamin...
关键词：Α-SYNUCLEIN L-Buthionine-SR-Sulfoximine N-ACETYL-L-CYSTEINE GLUTATHIONE SH-SY5Y Cells Parkinson’s Disease 
Oxidative stress, antioxidants and intestinal calcium absorption被引量：24
《World Journal of Gastroenterology》2017年第16期2841-2853,共13页Gabriela Diaz de Barboza Solange Guizzardi Luciana Moine Nori Tolosa de Talamoni 
Supported by Dr.Nori Tolosa de Talamoni from CONICET,No.PIP 2013-2015 and No.SECYT(UNC)2016,Argentina
The disequilibrium between the production of reactive oxygen(ROS) and nitrogen(RNS) species and their elimination by protective mechanisms leads to oxidative stress. Mitochondria are the main source of ROS as by-produ...
关键词：Transcellular and paracellular Ca2+pathways DL-buthionine-S R-sulfoximine MENADIONE Sodium deoxycholate Lithocholic acid Ursodeoxycholic acid MELATONIN 
The timing and extent of intraosseous hypoxia in the oxidative stress-induced rat osteonecrosis model
《Advances in Bioscience and Biotechnology》2013年第8期814-817,共4页Toru Ichiseki Ayumi Kaneuji Seiji Kaneko Syusuke Ueda Yoshimichi Ueda Hideto Yonekura Kiyokazu Fukui Tadami Matsumoto 
Using a rat oxidative stress-induced femoral head osteonecrosis model, we determined the presence/ absence and timing of the generation of hypoxia in the femoral head. DL-Buthionine-(S,R)-sulfoximine (BSO) 500 mg/kg w...
关键词：OSTEONECROSIS Oxidative Stress Buthionine SULFOXIMINE Hypoxia-Inducible Factor-1α 
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