supported by the Key-Area Research and Development Program of Guangdong Province(No.2023B1111050008);the National Natural Science Foundation of China(Nos.U23A20528,U20A20101);Guangdong Local Innovation Team Program(No.2019BT02Y262);the Postdoctoral Fellowship Program of CPSF(No.GZC20232777).
Seven novel linear polyketides,talaketides A-G(1-7),were isolated from the rice media cultures of the mangrove sed-iment-derived fungus Talaromyces sp.SCSIO 41027.Among these,talaketides A-E(1-5)represented unpreceden...
supported in part by the National Science and Technology Major Project(No.2021 YFC2301803);Shenzhen Fund for Guangdong Provincial High-Level Clinical Key Specialties(No.SZGSP011);Science and Technology Program of Shenzhen,China(No.JCYJ 20230807143411023);the clinical research project of Shenzhen Third Peoples Hospital(No.G2022044);the Teaching Quality and Teaching Reform Project of Education Department of Guangdong Province:Experimental Teaching Demonstration Center of Emerging Infectious Diseases(Y01411846).
Inborn errors of the signal transducer and activator of transcription 1(STAT1)result in four types of immunodeficiency disease with varying degrees of impaired STAT1 function:autosomal recessive(AR)complete STAT1 defi...