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作品数:2956被引量:4808H指数:25
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相关领域:医药卫生更多>>
相关作者:李一乔蒋伶活杨京鹏霍鑫红陈安民更多>>
相关机构:浙江大学浙江师范大学北京师范大学浙江省人民医院更多>>
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相关基金:国家自然科学基金国家重点基础研究发展计划国家教育部博士点基金中国博士后科学基金更多>>
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Unraveling brain aging through the lens of oral microbiota
《Neural Regeneration Research》2025年第7期1930-1943,共14页Qinchao Hu Si Wang Weiqi Zhang Jing Qu Guang-Hui Liu 
supported by the National Natural Science Foundation of China,No.81921006(to GHL)。
The oral cavity is a complex physiological community encompassing a wide range of microorganisms.Dysbiosis of oral microbiota can lead to various oral infectious diseases,such as periodontitis and tooth decay,and even...
关键词:Alzheimer's disease brain aging multiple sclerosis NEURODEGENERATION neurodegenerative diseases oral microbiota Parkinson's disease PERIODONTITIS BACTERIA Porphyromonas gingivalis 
Neuroinflammation revisited through the microglial lens
《Neural Regeneration Research》2025年第7期1989-1990,共2页Renato Socodato João B.Relvas 
funded by Portuguese funds through FCT——Funda??o para a Ciência e a Tecnologia/Ministério da Ciência,Tecnologia e Ensino Superior in the framework of the project PTDC/MEDNEU/1677/2021(to JBR)。
Neuroimmunology is emerging as a pivotal field,shedding light on the intricate dialogues between the central nervous system(CNS)and the immune system.This exploration is particularly significant in understanding micro...
关键词:INFLAMMATION simplified ACTIVATION 
Predicting anti-cancer drug sensitivity through WRE-XGBoost algorithm with weighted feature selection
《Genes & Diseases》2025年第2期15-17,共3页Yiyao Jiang Ming Chen Zhongmin Xiong Yufang Qin 
supported in part by the Shanghai Science and Technology Innovation Action Planning (No.20dz1203800 to M.C.);the Research and Development Planning in Key Areas of Guangdong Province,China (No.2021 B0202070001 to M.C.);the National Natural Sci-ence Foundation of China (No.61702325 to Y.Q.).
Accurate prediction of drug susceptibility is one of themost important steps in personalized medicine.Applications of machine learning to pharmacogenomic data for sensitivity prediction can help study the mechanism of...
关键词:STEPS SUSCEPTIBILITY ALGORITHM 
Elucidating Secondary Organic Aerosol Processes through High-Resolution Aerosol Mass Spectrometry in Beijing
《Advances in Atmospheric Sciences》2025年第4期670-681,共12页Weiqi XU Chun CHEN Zhijie LI Zhiqiang ZHANG Yu ZHANG Zifa WANG Yele SUN 
supported by the Strategic Priority Research Program of the Chinese Academy of Sciences(Grant No.XDB0760200);the National Natural Science Foundation of China(Grant No.42377101,91744207).
Exploring secondary organic aerosol(SOA)processes is crucial for understanding climate and air pollution in megacities.This study introduces a new method using positive matrix factorization(PMF)to investigate the SOA ...
关键词:secondary organic aerosol positive matrix factorization aerosol mass spectrometry nitrogen-enriched organic aerosol sulfur-enriched organic aerosol 
Enhancing orthodontic osteodilated arch treatment through comprehensive nursing interventions and cognitive behavioral therapy
《World Journal of Clinical Cases》2025年第12期1-4,共4页Haewon Byeon 
Basic Science Research Program Through the National Research Foundation of Korea Funded by the Ministry of Education,No.NRF-RS-2023-00237287 and No.NRF-2021S1A5A8062526;Local Government-University Cooperation-Based Regional Innovation Projects,No.2021RIS-003.
Orthodontic osteodilated arch treatment represents a pivotal approach in dental orthodontics to address dental crowding and misalignment.Integrating cognitive behavioral therapy(CBT)into comprehensive nursing interven...
关键词:Cognitive behavioral therapy Comprehensive nursing interventions Orthodontic care Patient compliance Psychological well-being 
Candida albicans and colorectal cancer:A paradoxical role revealed through metabolite profiling and prognostic modeling
《World Journal of Clinical Oncology》2025年第4期195-279,共85页Hao-Ling Zhang Rui Zhao Di Wang Siti Nurfatimah Mohd Sapudin Badrul Hisham Yahaya Mohammad Syamsul Reza Harun Zhong-Wen Zhang Zhi-Jing Song Yan-Ting Liu Sandai Doblin Ping Lu 
Supported by Gansu Province Joint Fund General Program,No.24JRRA878;Gansu Provincial Science and Technology Program Project,No.24JRRA1020;Gansu Province Key Talent Program,No.2025RCXM006;Teaching Research and Reform Program for Postgraduate Education at Gansu University of Traditional Chinese Medicine(GUSTCM),No.YBXM-202406;Special Fund for Mentors of“Qihuang Talents”in the First-Level Discipline of Chinese Medicine,No.ZYXKBD-202415。
BACKGROUND Emerging evidence implicates Candida albicans(C.albicans)in human oncogenesis.Notably,studies have supported its involvement in regulating outcomes in colorectal cancer(CRC).This study investigated the para...
关键词:Candida albicans Colorectal cancer Metabolic characteristics Extracellular ATP Prognostic model 
Trichostatin A augments cell migration and epithelial-mesenchymal transition in esophageal squamous cell carcinoma through BRD4/c- Myc endoplasmic reticulum-stress pathway
《World Journal of Gastroenterology》2025年第11期164-182,共19页Yan-Min Chen Wen-Qian Yang Ying-Ying Fan Zhi Chen Yu-Zhen Liu Bao-Sheng Zhao 
Supported by the Henan Province Science and Technology Development Plan,No.242102311124;Key Medical Scientific and Technological Project of Henan Province,No.SBGJ202102188;Henan Provincial Medical Science and Technology Project,No.LHGJ20221012;Fundamental Research Funds for the Universities of Henan Province,No.NSFRF240308.
BACKGROUND The causes of death in patients with advanced esophageal cancer are multi-factorial,with tumor metastasis being one of the important factors.Histone acetylation promotes the migration of esophageal squamous...
关键词:Esophageal squamous cell carcinoma Histone deacetylase inhibitor Trichostatin A Endoplasmic reticulum stress Epithelial-mesenchymal transition Cell migration 
Nursing students’experiences with improving cultural competence through education and practices in rural Indonesia:a qualitative study
《Frontiers of Nursing》2025年第1期37-46,共10页Petrus Kanisius Siga Tage Fepyani Thresna Feoh Maria Yasintha Goa Angela Muryanti Gatum Herliana Monika Azi Djogo Erna Febriyanti 
supported by an internal grant from Universitas Citra Bangsa(Number 6/VI/LP3M/UCB/22).
Objective: The importance of culture in nursing lies in its influence on patients’ health perceptions, behaviors, and responses to care. Despite the challenges posed by the complexity of studying culture, there remai...
关键词:cultural competency EDUCATION Indonesia nursing students PRACTICE qualitative research RURAL 
Dendrobium officinale extract exerts antioxidant effects against skin photoaging through MMP9-TNF pathway
《Traditional Medicine Research》2025年第3期32-41,共10页Bei-Bei Dong Yun Wang Han Zhao Wu-Yan Guo Bo Zhang 
Background:Skin photoaging is a physiological or pathological process caused by multiple factors.Developing anti-skin photoaging drugs is a hot topic in cosmetology research fields.The purpose of this study was to exp...
关键词:Dendrobium officinale skin photoaging matrix metalloproteinase anti-oxidative stress 
N6-methyladenosine methyltransferase Wilms tumor 1-associated protein impedes diabetic wound healing through epigenetically activating DNA methyltransferase 1
《World Journal of Diabetes》2025年第3期232-242,共11页Ren-Jie Xiao Tian-Jiao Wang Dan-Yin Wu Shui-Fa Yang Hai Gao Pei-Dong Gan Yang-Yan Yi You-Lai Zhang 
BACKGROUND Diabetic wound injury is a significant and common complication in individuals with diabetes.N6-methyladenosine(m6A)-related epigenetic regulation is widely involved in the pathogenesis of diabetes complicat...
关键词:Diabetic wound healing N6-methyladenosine Wilms tumor 1-associated protein DNA methyltransferase 1 Human umbilical vein endothelial cells 
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