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TRANSDUCTION: 作品数：235被引量：650H指数：13; 导出分析报告; 相关领域：医药卫生生物学更多>>; 相关作者：张罗韩德民卢从明张建华贾文锁更多>>; 相关机构：首都医科大学中国科学院上海生命科学研究院四川大学中国农业大学更多>>; 相关期刊：更多>>; 相关基金：国家自然科学基金国家重点基础研究发展计划国家高技术研究发展计划北京市科技计划项目更多>>

Taurine Transporter dEAAT2 is Required for Auditory Transduction in Drosophila被引量：4: 《Neuroscience Bulletin》2018年第6期939-950,共12页Ying Sun Yanyan Jia Yifeng Guo Fangyi Chen Zhiqiang Yan; supported by funds from The Ministry of Science and Technology of China (2017YFA0103900 and 2016YFA0502800);The National Natural Science Foundation of China (31571083);supported by The National Natural Science Foundation of China (81470701);The National Natural Science Foundation of China (81771882);The Program for Professor of Special Appointment (Eastern Scholar of Shanghai; TP2014008);The Shanghai Rising-Star Program (14QA1400800);a grant from the Young 1000 Talent Program of China to ZY;The Fundamental Research (Discipline Layout) Foundation from Shenzhen Committee of Science, Technology and Innovation (JCYJ20170817111912585) to FC; Drosophila dEAAT2, a member of the excitatory amino-acid transporter(EAAT) family, has been described as mediating the high-affinity transport of taurine, which is a free amino-acid abundant in both insects and mammal...; 关键词：Drosophila dEAAT2 TAURINE Chordotonal neurons Sound transduction

An efficient strategy for generation of transgenic mice by lentiviral transduction of male germline stem cells in vivo被引量：1: 《Journal of Animal Science and Biotechnology》2016年第2期158-166,共9页Jinzhou Qin Haixia Xu Pengfei Zhang Conghui Zhang Zhendong Zhu Rongfeng Qu Yuwei Qin Wenxian Zeng; supported in part by National Basic Research Program of China (973 program; 2013CB943103);the National Natural Science Foundation of China (Grant No. 31072029, No.31272439, No. C170104 and No. 31230048);Ph.D. Programs Foundation of Ministry of Education of China (Grant No.20130204110017) for W. Zeng and W Dong;the scholarship from China Scholarship Council (CSC); Background： Male germline stem cells（MGSCs） are a subpopulation of germ cells in the testis tissue. MGSCs are capable of differentiation into spermatozoa and thus are perfect targets for genomic manipulation to gen...; 关键词：In vivo Lentivirus vectors Male germline stem cells Transgenesis

Cell type specificity of signaling:view from membrane receptors distribution and their downstream transduction networks: 《Protein & Cell》2012年第9期701-713,共13页Ying He Zhonghao Yu Dongya Ge Rui Wang-Sattler Hans-Jurgen Thiesen Lu Xie Yixue Li; kindly funded by National Natural Science Foundation of China(Grant No.31070752);in part supported by the National Basic Research Program(973 Program)(Nos 2011CB910204,2010CB529206 and 2010CB912702);Key Infectious Disease Project(No.2012ZX10002012-014);Research Program of Chinese Academy of Sciences(Nos.KSCX2-EW-R-04,KSCX2-YW-R-190 and 2011KIP204);National Natural Science Foundation of China(Grant No.30900272);Chinese Ministry for Science and Technology Grant(No.2008BAI64B01);the National High Technology Research and Development Program(863 Program)(No.2009AA02Z304).; Studies on cell signaling pay more attention to spatial dynamics and how such diverse organization can relate to high order of cellular capabilities.To overview the specificity of cell signaling,we integrated human re...; 关键词：plasma membrane receptor cellular signaling transduction network diversity cell type specific spatial expression profile

Expression and function of aquaporins in peripheral nervous system被引量：6: 《Acta Pharmacologica Sinica》2011年第6期711-715,共5页Tong-hui MA Hong-wen GAO Xue-dong FANG Hong YANG; This work was supported by National Natural Science Foundation （No 30670477）, Dalian Municipal Science and Technology Fund （2008E11SF162）, and National Basic Research Program of China （＂973＂ Program, No 2009CB521908）.; The expression and role of the aquaporin （AQP） family water channels in the peripheral nervous system was less investigated. Since 2004, however, significant progress has been made in the immunolocalization, regulat...; 关键词：AQUAPORINS peripheral nervous system neuronal transduction gene knockout gene expression PAIN

The endocrine regulation network of growth hormone synthesis and secretion in fish: Emphasis on the signal integration in somatotropes被引量：12: 《Science China(Life Sciences)》2010年第4期462-470,共9页LI WenSheng & LIN HaoRan State Key Laboratory of Biocontrol, Institute of Aquatic Economic Animals and the Guangdong Provincial Key Laboratory for Aquatic Economic Animals, School of Life Sciences, Sun Yat-sen University, Guangzhou 510275, China; supported by the National Basic Research Program of China (Grant No. 2010CB126302);the Earmarked Fund for Modern Agro-industry Technology Research System for Tilapia;the Agriculture Research Special Funds of 3-49;the National High Technology Research and Development Program of China (Grant No. 2007AA091404) to Dr. Li WenSheng; In teleosts, growth hormone (GH) production is governed by multiple neuroendocrine factors from the hypothalamus and other regulators from the pituitary and peripheral organs. Exploring the principles followed by pitu...; 关键词：FISH growth HORMONE RECEPTOR signal TRANSDUCTION

Interference RNA induction and drug target validation: 《Journal of Chinese Pharmaceutical Sciences》2009年第4期293-301,共9页金鑫孙婷婷王琪徐欢魏铁军贺秋晨张礼和周德敏; National Natural Science Foundation of China(Grant No.20852001);"985"Project Foundation(Grant No.985-2-126-121 );The Key Laboratory Grant(Grant No.20080104);National Basic Research Program of China(Grant No.973 Program,2010CB 12300); The ability to knockdown the expression of an endogenous gene by RNAi has emerged as a powerful strategy for the rapid identification of specific gene functions. Vector-based constitutive expression of shRNA can resul...; 关键词：RNA interference Stable transduction Inducible RNAi Target validation Xenograft animal model

FADDdel-GFP-Modified Mouse Insulinoma Cells Counteract the Cytotoxicity of Reactive T Cells: 《Cellular & Molecular Immunology》2004年第5期383-386,共4页PingHu GuohuaWang XiaohuaZhu JingYang HuifenZhu ZihuiXu WenjunLiao XiaoLiu FenXu JiaoYin GuanxinShen; This study was supported by National Key Basic Research Program of China(No.CB5 10008);National Natural Science foundation(No.30300166).; IDDM results from pancreatic beta cell destruction by islet-reactive T cells,a process that involves beta cell apoptosis.Fas-FasL pathway plays a major role in pancreatic β cell death.Fas-associated death domain prot...; 关键词：FADD NIT TRANSDUCTION

Molecular mechanism of signaling by tumor necrosis factor被引量：2: 《Science China(Life Sciences)》2002年第2期113-119,共7页查纪坤舒红兵; This work was supported by the National Outstanding Youth Foundation of China (Grant No. 39925016); National Basic Science Researches Program (Grant No. G19990539) and Peking University.; Tumor necrosis factor (TNF) is an important cytokine with multiple biological effects, including cell growth, differentiation, apoptosis, immune regulation and induction of inflammation. The effects of TNF are mediate...; 关键词：tumor NECROSIS factor signal transduction JNK kinase NF-κB apoptosis.

Identification of integrin-like in guard cells of Vicia faba: 《Chinese Science Bulletin》2001年第13期1100-1103,共4页ZHANG Aihua HUANG Rongfeng WANG Xuechen YUAN Ming; This work was supported by the Major State Basic Research Program of China (Grant No. G1999011704); and the National Natural Science Foundation of China (Grant No. 39730050).; We addressed the existence and localization of integrin-like in guard cells of Vicia faba by using a probe of polyclonal antibody against the human integrin (αvβ3/β5)-Western blot results showed that three integrin...; 关键词：integrins-like GUARD cells VICIAFABA signal transduction.

Characterization of Energy_Transduction in Thermal Pretreated Chloroplast from Spinach: 《Acta Botanica Sinica》2001年第1期29-35,共7页彭建新万常照邹永龙陈根云钱月琴袁勤王国强; SupportedbytheStateKeyBasicResearchandDevelopmentPlanofChina (G19980 10 0 0 ) ;KeyPlanoftheNationalNaturalScienceFoundationofChi; Characterization of energy-transduction on die chloroplast thylakoid membranes from spinach (Spinacia oleracca L.) after thermal pretreatment was investigated. The related reactions of energy-transduction in chloropla...; 关键词：Spinacia oleracea CHLOROPLAST thermal pretreatment energy-transduction permeability of thylakoid membranes coupling factor complex

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