supported by National Institutes of Health grants RF1NS076815 and R01AG058621.
Currently,more than 55 million people have dementia worldwide and Alzheimer’s disease(AD)is one of the most common causes of dementia in aging.However,no effective therapies are currently available for the prevention...
supported by the National Natural Science Foundation of China(No.81973665);the Science and Technology Innovation Program of Hunan Province(No.2021RC3030);the Fundamental Research Funds for the Central Universities of Central South University(No.2021zzts1028);the InnovationDriven Project of Central South University(No.2020CX047).
To repair the blood–brain barrier(BBB)after traumatic brain injury(TBI)remains a multidisciplinary challenge.No first-line drugs are available.Here,we reported a novel and non-toxic functional negative-charged carbon...
supported by the National Natural Science Foundation of China,Nos.81974189(to HLT),81801236(to QYG and LC),82001310(to DXY).
Urolithin A(UA)is a natural metabolite produced from polyphenolics in foods such as pomegranates,berries,and nuts.UA is neuroprotective against Parkinson’s disease,Alzheimer’s disease,and cerebral hemorrhage.However...
Traumatic brain injury(TBI)is a major cause of morbidity and mortality worldwide.Despite significant medical advances over recent decades,many survivors of TBI develop long term neuro-cognitive deficits.Previously,onl...
Traumatic brain injury(TBI)remains one of the leading causes of disability and death in infants and children.Studies have demonstrated that the youngest age group(especially≤4 years old)exhibit worse functional o...
Traumatic brain injury (TBI) is an acquired injury to the brain that occurs with sudden trauma that can range from mild (concussive) to severe. TBI is considered a leading cause of death in children and young adul...
supported by NIH NS073636(RS/XMX),NS059622;DOD CDMRP W81XWH-12-1-0562,DVA 1I01BX002356-01A1,Craig H Neilsen Foundation 296749;Indiana Spinal Cord and Brain Injury Research Foundation and Mari Hulman George Endowment Funds(XMX),and by the State of Indiana(ISDH,Grant#A70-2-079609,A70-9-079138 and A70-5-0791033,NKL);supported by a grant from China Scholarship Council(CSC-201306170108)to WQ
Traumatic brain injury often causes a variety of behavioral and emotional impairments that can develop into chronic disorders. Therefore, there is a need to shift towards identifying early symptoms that can aid in the...
funded by the National Institutes of Health Grant No.NS078710
Traumatic brain injury is a major health problem worldwide. Currently, there is no effective treatment to improve neural structural repair and functional recovery of patients in the clinic. Cell transplantation is a p...
While it is well-known that neuronal activity promotes plasticity and connectivity, the success of activity-based neural rehabilitation programs remains extremely limited in human clinical experience because they cann...