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TUMOR_CELLS: 作品数：309被引量：1150H指数：17; 导出分析报告; 相关作者：石学耕李慧史桂英易静高飞更多>>; 相关机构：北京大学中国科学院上海生命科学研究院中国医学科学院上海第二医科大学更多>>; 相关期刊：更多>>; 相关基金：国家自然科学基金国家重点基础研究发展计划国家高技术研究发展计划中国博士后科学基金更多>>

Role of PFKM lactylation in glycolysis regulation in endometrial cancer cells: 《Genes & Diseases》2025年第3期27-30,共4页Bin Wang Jian Ma Di Yang; supported by the National Natural Science Foundation of China(No.82203469);the Liaoning Province Joint Fund General Project(China)(No.2023-MSLH-166).; The incidence of endometrial cancer(EC)is increasing,particularly in high-risk cases with poor prognosis.1 Reprogramming glucose metabolism is the main feature of energy metabolism in EC cells,resulting in substantial...; 关键词：lactic acid PFKM lactylation endometrial cancer ec reprogramming glucose metabolism glycolysis regulation metabolic process tumor cells modifying key proteins

Dual-Mode Colorimetric and Fluorescent Detection of Tumor Cells Based on Gold Nanoparticles-Loaded Phosphine Covalent Organic Frameworks: 《Journal of Analysis and Testing》2025年第1期21-31,共11页Bilian Li Min Zhou Chun Zhao Lin Xiao Tianle Qi Hanbin Xu Linjiang Guo Guobao Ning Xiaokang Lu Keming Zhu Hui Zhao Can-Peng Li; financially supported by Major science and technology project of Yunnan Province(202302AE090022);Key Research and Development Program of Yunnan(202203AC100010);the National Natural Science Foundation of China(32160597,32160236,32371463);National Key Research and Development Program of China(2022YFC2601604);Cardiovascular Ultrasound Innovation Team of Yunnan Province(202305AS350021);Spring City Plan:the High-level Talent Promotion and Training Project of Kunming(2022SCP001);the Association Foundation Program of Yunnan Provincial Science and TechnologyDepar tment;Kunming Medical University(202101AY070001-278);the second phase of“Double-First Class”program construction of Yunnan University。; Circulating tumor cells(CTCs)are important markers for cancer.The part of tumor cells that are detached from the primary tumor or metastatic tumor and enter the blood circulation is called CTCs.It is crucial to develo...; 关键词：Phosphine covalent organic frameworks Circulating tumor cells Colorimetric and fluorescent dual mode detection Liquid biopsy Cytosensor

Research and analysis of circulating tumor cell detection in the diagnosis and treatment of gastric cancer: 《World Journal of Gastrointestinal Oncology》2025年第3期165-170,共6页Han-Shu Ji; Hebei Provincial Health Commission Project,No.20210876.; BACKGROUND Circulating tumor cells(CTCs)are crucial for improving our knowledge regarding tumor progress,prognosis,and recurrence possibility.AIM To evaluate the role of CTCs in the early diagnosis and treatment of ga...; 关键词：Gastric cancer CIRCULATION Tumor cells Early diagnosis Randomized controlled trial

The Tricarboxylic Acid Cycle Metabolites for Cancer:Friend or Enemy: 《Research》2025年第1期385-409,共25页Jie Wu Nian Liu Jing Chen Qian Tao Qiuqiu Li Jie Li Xiang Chen Cong Peng; supported by grant nos.82073458,82173424,81974476,and 82221002 from the National Natural Science Foundation;by grant from The Scientific Research Program of FuRong Laboratory(no.2023SK2103);by the Science and Technology Innovation Program of Hunan Province(2021RC4013);as well as the key project in Hunan province(2024JJ3052).; The tricarboxylic acid(TCA)cycle is capable of providing sufficient energy for the physiological activities under aerobic conditions.Although tumor metabolic reprogramming places aerobic glycolysis in a dominant posit...; 关键词：aerobic glycolysis tricarboxylic acid cycle tumor metabolic reprogramming amino acidstca tumor cells metabolic reprogramming ketoglutarate CITRATE

Automatic detection method of bladder tumor cells based on color and shape features: 《Journal of Innovative Optical Health Sciences》2024年第6期1-13,共13页Zitong Zhao Yanbo Wang Jiaqi Chen Mingjia Wang Shulong Feng Jin Yang Nan Song Jinyu Wang Ci Sun; Bethune Medical Engineering and Instrument Center Fund(E10133Y8H0);Jilin province science and technology development plan project(20210204216YY,20210204146YY).; Bladder urothelial carcinoma is the most common malignant tumor disease in urinary system,and its incidence rate ranks ninth in the world.In recent years,the continuous development of hyperspectral imaging technology ...; 关键词：Bladder tumor cells microscopic hyperspectral fusion feature support vector machine automatic detection.

Oncological Hyperthermia: Where to Go from Here?: 《Open Journal of Biophysics》2024年第4期355-373,共19页Andras Szasz; Oncological hyperthermia is one of the most versatile forms of oncotherapy. It can complement every conventional treatment method and be applied to any tumorous cancer, irrespective of its stages and localization. Num...; 关键词：Thermal Nonthermal Modulated Electrohyperthermia Selection of Tumor Cells Tumor-Specific Immune Activity Abscopal Effect

Retraction:Long noncoding RNA urothelial carcinoma-associated 1 promotes the proliferation and metastasis of human lung tumor cells by regulating MicroRNA-144: 《Oncology Research》2024年第11期1825-1825,共1页Oncology Research Editorial Office; Following the publication,concerns have been raised about a number of figures in this article.The western blots in this article were presented with atypical,unusually shaped and possibly anomalous protein bands in man...; 关键词：METASTASIS raised concerned

Celastrol activates caspase-3/GSDME-dependent pyroptosis in tumor cells by inducing endoplasmic reticulum stress Author links open overlay panel: 《Journal of Traditional Chinese Medical Sciences》2024年第3期330-339,共10页Jiajian Guo Dongxiao Cui Yuping Tang Sanjiao Wang Cuiyan Ma Wenfu Ma; supported by grants from startup fund program at Beijing University of Chinese Medicine(90011451310011);key research fund for drug discovery in Chinese medicine at Beijing University of Chinese Medicine(1000061223476);startup fund program at Beijing University of Chinese Medicine(90020361220006).; Objective:To investigate the pyroptosis-inducing effects of celastrol on tumor cells and to explore the potential mechanisms involved,specifically focusing on the role of the caspase-3/gasdermin E(GSDME)signaling path...; 关键词：CELASTROL Tumor cells PYROPTOSIS GSDME CASPASE-3 Endoplasmic reticulum stress stress Cell death Traditional Chinese medicine

From small to large-The application of in situ polymerization within tumor cells: 《Aggregate》2024年第4期33-53,共21页Mingjie Jia Yonghang Liu Peng Wei Tao Yi; National Natural Science Foundation of China,Grant/Award Numbers:22371038,22377010,22177019;Fundamental Research Funds for the Central Universities,Grant/Award Number:2232021A-06。; The“laboratory”of cells has the capacity to polymerize monosaccharides,amino acids,and nucleotides.Tumor cells,characterized by the overexpression of multi-ple enzymes and existing in a slightly acidic and highly re...; 关键词：in situ POLYMERIZATION tumor cell

Bcl-xL regulates radiation-induced ferroptosis through chaperone-mediated autophagy of GPX4 in tumor cells: 《Radiation Medicine and Protection》2024年第2期90-99,共10页Jing Han Ruru Wang Bin Chen Feng Xu Liangchen Wei An Xu Lijun Wu Guoping Zhao; the National Science Fund for Excellent Young Scholars(grant number 12122510);the National Natural Science Foundation of China(grant number 32171240);Anhui Provincial Natural Science Foundation(grant numbers 2108085MH279);the HFIPS Director’s Fund(grant numbers BJPY2021B07 and BJPY2023A010).; Objective:To investigate the role and the molecular mechanisms of apoptotic signaling in ferroptosis to regulate tumor radiosensitivity.Methods:Reactive oxygen species(ROS)and lipid peroxide levels were detected in Mo...; 关键词：BCL-XL Ferroptosis GPX4 Chaperone-mediated autophagy Lipid peroxidation

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