supported by the National Key Research and Development Program of China(2023YFF1000200);the National Natural Science Foundation of China(U21A20276);the Tencent Foundation through the XPLORER PRIZE and the New Cornerstone Science Foundation to Z.H.,Heilongjiang Touyan Team(HITTY-20190034 to Z.H.);Natural Science Foundation of Heilongjiang Province of China(YQ2023C032 to Y.Z.)。
In the ongoing arms race between bacteria and bacteriophages,bacteriophages have evolved anti-CRISPR proteins to counteract bacterial CRISPR-Cas systems.Recently,AcrⅡA25.1 and AcrⅡA32 have been found to effectively ...