ADJUVANT

作品数：496被引量：1918H指数：20
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A phase 2 pilot study of umbilical cord blood infusion as an adjuvant consolidation therapy in elderly patients with acute myeloid leukemia
《Signal Transduction and Targeted Therapy》2025年第1期384-393,共10页Jinzeng Wang Xiaoyang Li Ping Liu Yao Dai Hongming Zhu Yunxiang Zhang Min Wu Yunying Yao Mingzhu Liu Shuting Yu Fangying Jiang Shuai Wang Haoran Mu Bo Jiao Hua Yan Wen Wu Yang Shen Junming Li Shengyue Wang Ruibao Ren 
supported by the Shanghai Science and Technology Development Funds(No.20Z11900200 to R.R.);Key Project of National Natural Science Foundation of China(No.82230088 to R.R.);National Key Research and Development Program of China(No.2019YFA0905900 to J.L.;No.2019YFA0905902 to S.W.),National Natural Science Foundation of China(No.82170147 to R.R.;No.82370157 to J.L.;No.81970134 and 82170111 to P.L.);Shanghai Collaborative Innovation Program on Regenerative Medicine and Stem Cell Research(No.2019CXJQ01 to R.R.);the Samuel Waxman Cancer Research Foundation(to R.R.).
Acute myeloid leukemia(AML)is an aging-related malignancy,with patients aged≥60 years old facing significantly poorer prognosis.Umbilical cord blood(UCB)has emerged as a promising source with effective anti-aging rol...
关键词：INFUSION PATIENTS ADJUVANT 
CRX-527 as a candidate adjuvant in a recombinant BCG-based malaria vaccine被引量：2
《Asian Pacific Journal of Tropical Biomedicine》2024年第1期1-7,共7页Nor Munirah Zakaria Muhammad Adamu Abbas Rapeah Suppian 
supported by the Ministry of Higher Education Malaysia for Fundamental Research Grant Scheme with Project Code:FRGS/1/2021/SKK06/USM/002/4.
Objective:To investigate the role of CRX-527,a Toll-like receptor 4 agonist,as the possible adjuvant for recombinant Mycobacterium bovis Bacillus Calmette-Guerin expressing merozoite surface protein 1C(BCG-MSP-1C).Met...
关键词：CRX-527 BCG BCG-MSP-1C TLR-4 agonists Cytokine IgG MALARIA 
Oral PLGA-based DNA vaccines using interferons as adjuvants remarkably promote the immune protection of grass carp(Ctenopharyngodon idella)against GCRV infection
《Water Biology and Security》2023年第2期91-101,共11页Chaolin Jiang Xingchen Huo Lingjie Tang Meidi Hu Chunrong Yang Daji Luo Jianguo Su 
supported by the National Key R&D Program of China(2022YFF1000302);Major Project of Hubei Hongshan Laboratory(2022hszd011).
Grass carp hemorrhagic disease caused by grass carp reovirus(GCRV)results in significant economic losses to the global grass carp aquaculture industry.Oral vaccination is an ideal choice for disease precaution in aqua...
关键词：Grass carp(Ctenopharyngodon idella) Grass carp reovirus(GCRV) PLGA DNA vaccine INTERFERON ADJUVANT 
Liposomes as immunological adjuvants and delivery systems in the development of tuberculosis vaccine:A review
《Asian Pacific Journal of Tropical Medicine》2022年第1期7-16,共10页Nur Ellene Mat Luwi Suhana Ahmad Ahmad Suhaimi Nurfatihah Azlyna Asyikin Nordin Maria Elena Sarmiento Armando Acosta Mohd Nor Norazmi Vuk Uskoković Rohimah Mohamud Ramlah Kadir 
supported by Fundamental Research Grant Scheme (FRGS/1/2018/SKK08/USM/03/1),Ministry of Higher Education (Malaysia);Long-term Research Grant Scheme (LRGS/1/2015/USM/01/1/1),Ministry of Higher Education (Malaysia)
Liposomes are phospholipid bilayer vesicles,which are biocompatible,biodegradable and nontoxic vehicles suitable for numerous drug and gene delivery applications.In this review,we discuss the prospect of using liposom...
关键词：Liposomes Tuberculosis vaccine ADJUVANT Delivery system TUBERCULOSIS 
Revisiting GM-CSF as an adjuvant for therapeutic vaccines被引量：2
《Cellular & Molecular Immunology》2018年第2期187-189,共3页Weidong Zhao Gan Zhao Bin Wang 
This work is supported by grants from the National Science and Technology Major Program of Infectious Diseases(2012ZX10002002004-001,2012ZX10004701 and 2013ZX10002001);the Natural Science Foundation of China(31430027 and 81672016)to BW;We thank Dr Yan Shi for his critical review and suggestions and Dr Douglas Lowrie for his proofreading.
Granulocyte macrophage colony stimulating factor(GM-CSF)is generally considered to be a proinflammatory cytokine;GM-CSF-based vaccines have been shown to elicit potent antitumor and antiviral immune responses in precl...
关键词：vaccines CLINICAL stimulating 
Antitumor Effects of Newcastle Disease Virus Hemagglutinin-neuraminidase Used as a Molecular Adjuvant被引量：1
《Chemical Research in Chinese Universities》2013年第2期270-274,共5页JI Hui-fan CHI Bao-rong HE Dong-yun LI Chang HU Ning-ning WANG Kai SHENG Yuan WANG Hong-yu JIN Ning-yi 
Supported by the National Science and Technology Major Projects for Major New Drugs Innovation and Development of China（No.2010ZX09401-305-14）, the National Natural Science Foundation of China（Nos.81072210, 81101140） and the Key Technologies R＆D Program of Jilin Province of China（Nos. 10ZDGG007, 201015166, 201101066）.
Gene therapy is a potentially powerful tool used in cancer therapy. The strength of immune responses in- duced by some strategies is usually low, therefore, the development of agents capable of enhancing these respons...
关键词：Hemagglutinin-neuraminidase（HN） ADJUVANT Innate immunity Natural killer cell Antitumor immunity 
Feasibility Study of Aluminum Hydroxide Sol as Adjuvant to Prepare Stable Vaccine Using Newcastle Disease Virus as a Model被引量：1
《Wuhan University Journal of Natural Sciences》2011年第1期88-92,共5页SONG Meirong LI Xinsheng GAO Wenming FANG Shaoming CUI Baoan 
Supported by the National Science and Technology Supporting Program in the Eleventh Five-Year Plan of China (2006BAD06A08)
Aluminum hydroxide sol （consisting of aluminum hydroxide nano-particles） prepared by a hydrothermal method was used as nano-aluminum adjuvant adsorbed the inactived Newcastle disease virus （NDV）. The zeta potentia...
关键词：nano-aluminum adjuvant aluminum hydroxide sol Newcastle disease vaccine（NDV） hemagglutination inhibition（HI） titer 
CpG motifs behave as immunologic adjuvant in the peptide-based vaccine therapy of cancer
《中华肿瘤杂志》2007年第11期M0004-M0004,共1页
Synthetic peptides representing epitopes for antigen-specific CTL have been considered as prime candidates for vaccine development. However, in vivo administration of the peptides can activate T-cell response in some ...
关键词：CPG基序 免疫佐剂 癌症 基因治疗 肽 疫苗 
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