ADJUVANT

作品数:496被引量:1918H指数:20
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相关领域:医药卫生更多>>
相关作者:郭虹陈观今郑焕钦许小琴饶平凡更多>>
相关机构:中山大学吉林大学第二军医大学福州大学更多>>
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相关基金:国家自然科学基金国家重点基础研究发展计划中国博士后科学基金高等学校学科创新引智计划更多>>
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Immunotherapy and liver transplantation for hepatocellular carcinoma:Current and future challenges
《World Journal of Transplantation》2025年第2期8-29,共22页Theodoros Pettas Sofia Lachanoudi Filippos F Karageorgos Ioannis A Ziogas Asimina Fylaktou Vassilios Papalois Georgios Katsanos Nikolaos Antoniadis Georgios Tsoulfas 
Despite existing curative options like surgical removal,tissue destruction techniques,and liver transplantation for early-stage hepatocellular carcinoma(HCC),the rising incidence and mortality rates of this global hea...
关键词:Hepatocellular carcinoma IMMUNOTHERAPY Liver transplantation Neoadjuvant and adjuvant immunotherapy Immune checkpoint inhibitors Vaccine therapies Oncolytic viruses Adoptive cell therapy Antigen-targeting antibodies Diagnostic biomarkers 
A tumor-targeting nano-adjuvant for in situ vaccine based on ultrasound therapy
《Aggregate》2024年第3期290-298,共9页Linjie Cui Haochen Yao Fuxin Xue Jiali Sun Xitong Ren Mengfei Zheng Zhilin Liu Zhaohui Tang 
Ministry of Science and Technology of China,Grant/Award Number:2022YFE0110200;Natural Science Foundation of Jilin Province,Grant/Award Number:20230101037JC;National Natural Science Foundation of China,Grant/Award Numbers:52203198,52025035。
Ultrasound-generated antigens combined with TLR7/8 agonists as adjuvants have demonstrated significant anti-tumor efficacy as an in-situ vaccine.However,the use of TLR7/8 agonists can cause severe inflammatory respons...
关键词:IMMUNOTHERAPY in situ vaccine R848 nanoparticles TUMOR-TARGETING ultrasound therapy 
Self-adjuvant Astragalus polysaccharide-based nanovaccines for enhanced tumor immunotherapy:a novel delivery system candidate for tumor vaccines被引量:3
《Science China(Life Sciences)》2024年第4期680-697,共18页Nan Li Yun Zhang Miaomiao Han Tian Liu Jinjia Wu Yingxia Xiong Yikai Fan Fan Ye Bing Jin Yinghua Zhang Guibo Sun Xiaobo Sun Zhengqi Dong 
supported by Key Project at Central Government Level:the ability establishment of sustainable use for valuable Chinese medicine resources(2060302-2305-04);CAMS Innovation Fund for Medical Sciences(2021-1-I2M-031,2022-I2M-1-018,2022-I2M-2-002);Jilin Provincial Fiscal Construction Program for High-Tech Industries and Technologies(2022C041-5,20220401117YY);Hohhot Science and Technology Program(2021-Social-4)。
The study of tumor nanovaccines(NVs)has gained interest because they specifically recognize and eliminate tumor cells.However,the poor recognition and internalization by dendritic cells(DCs)and insufficient immunogeni...
关键词:Astragalus polysaccharides nanovaccines OVA IMMUNOTHERAPY self-adjuvant 
The Chinese Society of Clinical Oncology (CSCO): Clinical guidelines for the diagnosis and treatment of gastric cancer, 2023被引量:38
《Cancer Communications》2024年第1期127-172,共46页Feng-Hua Wang Xiao-Tian Zhang Lei Tang Qi Wu Mu-Yan Cai Yuan-Fang Li Xiu-Juan Qu Hong Qiu Yu-Jing Zhang Jie-Er Ying Jun Zhang Ling-Yu Sun Rong-Bo Lin Chang Wang Hao Liu Miao-Zhen Qiu Wen-Long Guan Sheng-Xiang Rao Jia-Fu Ji Yan Xin Wei-Qi Sheng Hui-Mian Xu Zhi-Wei Zhou Ai-Ping Zhou Jing Jin Xiang-Lin Yuan Feng Bi Tian-Shu Liu Han Liang Yan-Qiao Zhang Guo-Xin Li Jun Liang Bao-Rui Liu Lin Shen Jin Li Rui-Hua Xu 
The 2023 update of the Chinese Society of Clinical Oncology(CSCO)Clini-cal Guidelines for Gastric Cancer focuses on standardizing cancer diagnosis and treatment in China,reflecting the latest advancements in evidence-...
关键词:Chinese Society of Clinical Oncology(CSCO) gastric cancer diagnosis surgery NEOADJUVANT ADJUVANT RADIOTHERAPY chemotherapy targeted therapy IMMUNOTHERAPY 
Current trends in perioperative treatment of resectable gastric cancer被引量:2
《World Journal of Gastrointestinal Surgery》2023年第3期323-337,共15页İbrahim Yıldız Leyla Özer Elif Şenocak Taşçı İbrahim Vedat Bayoglu Erman Aytac 
In the last few decades,the treatment strategy for locally advanced resectable gastric cancer(GC)has shifted to a multimodal approach,which potentially decreases recurrence risk and improves survival rates.Perioperati...
关键词:Perioperative treatment IMMUNOTHERAPY NEOADJUVANT CHEMOTHERAPY Gastric cancer ADJUVANT 
Adjuvant and neo‐adjuvant immunotherapy in resectable non‐small cell lung cancer (NSCLC): Current status and perspectives被引量:1
《Cancer Innovation》2023年第1期65-78,共14页Ziyi Xu Zihua Zou Xuezhi Hao Puyuan Xing Junling Li 
Surgery followed by adjuvant chemotherapy is the standard of care for selectedpatients with early‐stage or locally advanced non‐small cell lung cancer(NSCLC). However, many of these patients still experience postope...
关键词:BIOMARKER peri‐operative immunotherapy resectable NSCLC 
Immunotherapy in Early Stage Non-Small Cell Lung Cancer
《Advances in Lung Cancer》2022年第3期31-44,共14页Jeyanthi Ramanarayanan Ganapathy Krishnan 
Immune-checkpoint inhibitors are extensively used in cancer treatment and have transformed the therapeutic landscape by inducing durable responses. Immunotherapy with checkpoint inhibitors targeting programmed death 1...
关键词:Non-Small Cell Lung Cancer IMMUNOTHERAPY Immune Checkpoint Inhibitors ADJUVANT NEOADJUVANT Early Stage 
Visualizable Delivery of Nanodisc Antigen-Conjugated Adjuvant for Cancer Immunotherapy被引量:1
《CCS Chemistry》2022年第4期1238-1250,共13页Yangyun Wang Subin Lin Hanqiu Jiang Yuan Gu Yanxian Wu Jie Ma Yubin Ke Leshuai W.Zhang Yong Wang Mingyuan Gao 
supported by National Natural Science Foundation of China(nos.21874097 and 12075164);National Key Research Program of China(no.2018YFA0208800);Suzhou Administration of Science and Technology(no.sys2018021);Jiangsu Province’s Natural Science Foundation(no.SBK2020041529);Pre-Research Foundation of the Second Affiliated Hospital of Soochow University(no.SDFEYBS1906);the Scientific Research Program for Young Talents of China National Nuclear Corporation;A Priority Academic Program Development of Jiangsu Higher Education Institutions(PAPD);the support by the Youth Innovation Promotion Association,Chinese Academy of Sciences(no.2020010).
Engineering synthetic vaccines is promising for improving the efficacy of cancer immunotherapy.One of the major challenges in the development of vaccines is achieving controllable codelivery of antigen and adjuvant to...
关键词:nanovaccines DC activation in vivo trafficking visualization IMMUNOTHERAPY 
Adjuvant immunotherapy in resected esophageal squamous cell carcinoma:a gospel to the non-pCRs
《Signal Transduction and Targeted Therapy》2021年第9期2611-2612,共2页Zhihui Zhang Nan Sun Jie He 
This work was supported by the CAMS Innovation Fund for Medical Sciences(2017-I2M-1-005).
A recent study1 published in The New England Journal of Medicine by Kelly RJ presented interim results from a phase 3 clinical trial(CheckMate 577),a global,randomized,double-blind,interventional trial to evaluate a n...
关键词:ESOPHAGEAL clinical KELLY 
The Chinese Society of Clinical Oncology(CSCO):Clinical guidelines for the diagnosis and treatment of gastric cancer,2021被引量:218
《Cancer Communications》2021年第8期747-795,共49页Feng-Hua Wang Xiao-Tian Zhang Yuan-Fang Li Lei Tang Xiu-Juan Qu Jie-Er Ying Jun Zhang Ling-Yu Sun Rong-Bo Lin Hong Qiu Chang Wang Miao-Zhen Qiu Mu-Yan Cai QiWu Hao Liu Wen-Long Guan Ai-Ping Zhou Yu-Jing Zhang Tian-Shu Liu Feng Bi Xiang-Lin Yuan Sheng-Xiang Rao Yan Xin Wei-Qi Sheng Hui-Mian Xu Guo-Xin Li Jia-Fu Ji Zhi-Wei Zhou Han Liang Yan-Qiao Zhang Jing Jin Lin Shen Jin Li Rui-Hua Xu 
There exist differences in the epidemiological characteristics,clinicopathological features,tumor biological characteristics,treatment patterns,and drug selections between gastric cancer patients from the Eastern and ...
关键词:ADJUVANT chemotherapy Chinese Society of Clinical Oncology(CSCO) diagnosis gastric cancer IMMUNOTHERAPY NEOADJUVANT RADIOTHERAPY surgery targeted therapy 
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