云南高校图书馆联盟文献共享服务平台- TUMOR-TARGETING

TUMOR-TARGETING: 作品数：27被引量：76H指数：5; 导出分析报告; 相关领域：医药卫生更多>>; 相关作者：杜惠娟更多>>; 相关机构：武汉工程大学复旦大学华中科技大学同济医学院附属协和医院更多>>; 相关期刊：《Asian Journal of Pharmaceutical Sciences》《Science Bulletin》《Bioactive Materials》《Acta Pharmacologica Sinica》更多>>; 相关基金：国家自然科学基金中国博士后科学基金北京市自然科学基金湖北省自然科学基金更多>>

A tumor-targeting nano-adjuvant for in situ vaccine based on ultrasound therapy: 《Aggregate》2024年第3期290-298,共9页Linjie Cui Haochen Yao Fuxin Xue Jiali Sun Xitong Ren Mengfei Zheng Zhilin Liu Zhaohui Tang; Ministry of Science and Technology of China,Grant/Award Number:2022YFE0110200;Natural Science Foundation of Jilin Province,Grant/Award Number:20230101037JC;National Natural Science Foundation of China,Grant/Award Numbers:52203198,52025035。; Ultrasound-generated antigens combined with TLR7/8 agonists as adjuvants have demonstrated significant anti-tumor efficacy as an in-situ vaccine.However,the use of TLR7/8 agonists can cause severe inflammatory respons...; 关键词：IMMUNOTHERAPY in situ vaccine R848 nanoparticles TUMOR-TARGETING ultrasound therapy

Tumor-targeting intravenous lipid emulsion of paclitaxel:Characteristics,stability,toxicity,and toxicokinetics被引量：1: 《Journal of Pharmaceutical Analysis》2022年第6期901-912,共12页Jun Ye Lin Li Jiye Yin Hongliang Wang Renjie Li Yanfang Yang Yongbiao Guan Xuejun Xia Yuling Liu; supported by the National Science and Technology Major Project of China(Grant No.:2018ZX09711001);Beijing Nova Program(Grant No.:Z211100002121127);Beijing Natural Science Foundation(Grant No.:L212059);Fundamental Research Funds for the Central Universities(Grant No.:3332021101);CAMS Innovation Fund for Medical Sciences(CIFMS,Grant No.:2022-I2M-JB-011).; Lipid nanoemulsions are promising nanodrug delivery carriers that can improve the efficacy and safety of paclitaxel(PTX).However,no intravenous lipid emulsion of PTX has been approved for clinical treatment,and system...; 关键词：Nanodrug delivery systems Lipid emulsion PACLITAXEL Colloidal Stability TOXICOKINETICS

Ras inhibitor farnesylthiosalicylic acid conjugated with IR783 dye exhibits improved tumor-targeting and altered anti-breast cancer mechanisms in mice被引量：1: 《Acta Pharmacologica Sinica》2022年第7期1843-1856,共14页Qiu-ju Huang Guo-chao Liao Xue-rong Zhuang Meng-lan Yang Jing-jing Yao Jian-hua Deng Yan-min Zhang Ying Wang Xiao-xiao Qi Dong-feng Pan Yang Guan Zhi-ying Huang Feng-xue Zhang Zhong-qiu Liu Lin-lin Lu; This work was supported by the projets of National Natural Science Foundation of China[81720108033,81930114,and 81874367];Natural Science Foundation_of Guangdong Province[2018B030322011];Natural Science_Foundation for Distinguished Young Scholars of Guangdong Province[2017A030306033].; Ras has long been viewed as a promising target for cancer therapy.Farnesylthiosalicylic acid(FTS),as the only Ras inhibitor has ever entered phase II clinical trials,has yielded disappointing results due to its strong...; 关键词：Ras inhibitor Farnesylthiosalicylic acid IR783 TUMOR-TARGETING breast neoplasm AMPK mTOR

Overcoming the obstacles of current photodynamic therapy in tumors using nanoparticles被引量：6: 《Bioactive Materials》2022年第2期20-34,共15页Donghyun Lee Soonmin Kwon Seok-young Jang Eunyoung Park Yeeun Lee Heebeom Koo; supported by Basic Research Program(2016R1C1B3013951,2021R1F1A1061286,and 2021R1A4A3031875)through the National Research Foundation of Korea(NRF)funded by the Korean government(Ministry of Science,ICT,and Future Planning).; Photodynamic therapy(PDT)has been applied in clinical treatment of tumors for a long time.However,insufficient supply of pivotal factors including photosensitizer(PS),light,and oxygen in tumor tissue dramatically redu...; 关键词：Photodynamic therapy NANOPARTICLE TUMOR-TARGETING Drug delivery Tissue penetration

Recent advances in tumor-targeting chemotherapy drugs: 《Cancer Drug Resistance》2021年第4期885-887,共3页Iwao Ojima; The first antibody-drug conjugate(ADC),Mylotarg,received FDA approval in 2000,and the revolutionary targeted cancer chemotherapy drug,Imatinib(Gleevec),was approved by FDA in 2001.Accordingly,it is an excellent time t...; 关键词：DRUGS CHEMOTHERAPY CANCER

Recent advances in tumor-targeting chemotherapy drugs: 《Cancer Drug Resistance》2021年第3期885-887,共3页Iwao Ojima; The first antibody-drug conjugate(ADC),Mylotarg,received FDA approval in 2000,and the revolutionary targeted cancer chemotherapy drug,Imatinib(Gleevec),was approved by FDA in 2001.Accordingly,it is an excellent time t...; 关键词：DRUGS CHEMOTHERAPY CANCER

Redox dual-stimuli responsive drug delivery systems for improving tumor-targeting ability and reducing adverse side effects被引量：7: 《Asian Journal of Pharmaceutical Sciences》2020年第3期311-325,共15页Ruirui Li Feifei Peng Jia Cai Dandan Yang Peng Zhang; National Natural Science Foundation of China (81202480,81302723);Natural Science Foundation of Liaoning Province (2015020749)。; Cancer is a big challenge that has plagued the human beings for ages and one of the most effective treatments is chemotherapy. However, the low tumor-targeting ability limits the wide clinical application of chemother...; 关键词：CHEMOTHERAPY Drug delivery system Redox responsive Dual-stimuli responsive TUMOR-TARGETING

NIR light-induced tumor phototherapy using ICG delivery system based on platelet-membrane-camouflaged hollow bismuth selenide nanoparticles被引量：10: 《Chinese Chemical Letters》2020年第5期1168-1172,共5页Kaili Ding Cuixia Zheng Lingling Sun Xinxin Liu Yanyan Yin Lei Wang; supported by the National Natural Science Foundation of China(Nos.81673021 and U1804183);the Scientific and Technological Project of Henan Province(No.182102310117)。; Near-infrared(NIR)light-triggered photothermal therapy(PTT)is a promising treatment strategy for treating cancer.The combination of nanotechnology and NIR has been widely applied.However,the therapeutic efficacy of th...; 关键词：Platelet membrane Biomimetic nanoplatform Photothermal therapy TUMOR-TARGETING Near-infrared laser irradiation

Amino acid transporters: Emerging roles in drug delivery for tumor-targeting therapy被引量：3: 《Asian Journal of Pharmaceutical Sciences》2020年第2期192-206,共15页Ling Zhang Chengguang Sui Wenhan Yang Qiuhua Luo; This work was supported by the National Natural Science Foundation of China(Nos.81803442 and 81703425).; Amino acid transporters,which play a vital role in transporting amino acids for the biosynthesis of mammalian cells,are highly expressed in types of tumors.Increasing studies have shown the feasibility of amino acid t...; 关键词：AMINO acid TRANSPORTER TUMOR-TARGETING Drug delivery PRODRUG NANOCARRIERS

Identification and characterization of mammaglobin-A epitope in heterogenous breast cancers for enhancing tumor-targeting therapy被引量：1: 《Signal Transduction and Targeted Therapy》2020年第1期1778-1788,共11页Zhiqiang Liu Xiqin Yang Cuimi Duan Jiangxue Li Rongsheng Tong Yuting Fan Jiannan Feng Ruiyuan Cao Wu Zhong Xiaoyan Feng Heqiu Zhang Lulu Cai; supported by the National Nature Science Foundation of China(81672607 and 81500077);the National Key Specialty Construction Project of Clinical Pharmacy(30305030698);the Nature Science Foundation of Beijing(7192143),the Beijing Nova Program(Z171100001117115);the Special Foundation for State Major Research Program of China(2016YFC0106603);the Research Funding of Sichuan Provincial People’s Hospital(2017LY08).; Although targeted therapy has been extensively investigated for breast cancers,a molecular target with broad application is currently unavailable due to the high heterogeneity of these cancers.Mammaglobin-A(Mam-A),whi...; 关键词：BREAST CANCERS EPITOPE

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