AMINO_ACID

作品数：541被引量：1251H指数：14
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Metabolic Control ofγδT Cell Function被引量：1
《Infectious Microbes & Diseases》2021年第3期142-148,共7页Ziyu Meng Guangchao Cao Quanli Yang Hengwen Yang Jianlei Hao Zhinan Yin 
supported by the grants from the National Natural Science Foundation of China(31830021 and 32030036 to ZY,31970830 to JH,32070121 to HY,31800722 to ZM);grant from the Ministry of Science and Technology of China(2020YFA0803500 to ZY),and grant from the Zhuhai Science and Technology Innovation Bureau(ZH22036302200063PWC to ZY).
Metabolic change is associated with cell activities,such as signal transduction,cell differentiation,and cell cycle.In the pathogenesis of autoimmune diseases,abnormal activation of T cells is often accompanied by cha...
关键词：γδT cells immunometabolism GLUCOSE fatty acid amino acid VITAMINS plant extract 
The reactive activities of natural amino acids: key principles of peptide-templated Au cluster synthesis被引量：1
《Science Bulletin》2016年第22期1732-1738,共7页Xu Li Nan Li Lina Zhao 
supported by the National Key Basic Research Program of China (2013CB932703, 2013CB933704);the National Natural Science Foundation of China (11404333, 31571026);the Special Program for Applied Research on Super Computation of the NSFC-Guangdong Joint Fund (the second phase)
Coating of gold nanoclusters with peptides is an important targeting method in biomedical applications.However, their synthetic method highly influences their targeting ability. Current methods often use harsh reagent...
关键词：Reactive activity Amino acid Synthesis in situ Au nanocluster DFT calculation 
Polymorphism of the 86th amino acid in CX26 protein and hereditary deafness
《Journal of Otology》2016年第2期84-87,共4页Xi Shi Shiwei Qiu Fendong Yan Lizhang Shi Yili Xuan Wei Zhuang Yingli Bei Hanli Yao Na Yuan Mingyang Shi Yuehua Qiao 
supported by grants from the National Basic Research Program of China (973 Program) (#2012CB967900);National Natural Science Foundation of China (31300624, 81470684);Postdoctoral Science Foundation of China (2015M571818);Six Major Categories Talent (2014-WSN043, 2011-WS-074);Innovation and Entrepreneurship Training Program for College Students in Jiangsu Province (201510313003Z, 201510313003, KYLX14-1455);Clinic Medical Special Foundation of Jiangsu province (b12014032)
Objective:To investigate the membrane localization function of the CX26 protein when its 86th amino acid is Thr, Ser or Arg, and its relations to deafness. Methods:CX26-GFP protein with either Thr, Ser or Arg as the 8...
关键词：Heredity deafness CX26 SGN 
Amino acid sensing in the gut and its mediation in gut-brain signal transduction被引量：4
《Animal Nutrition》2016年第2期69-73,共5页Jing Liu Kaifan Yu Weiyun Zhu 
supported by the National Key Basic Research Program of China (2013CB127300);Natural Science Foundation of China (31430082);Jiangsu Province Natural Science Foundation (BK20130058);the Collaborative Innovation Center of Meat Production and Processing
Animal gastrointestinal tract is not only a digestive organ, but also a nutrient sensing organ which detects luminal nutrient and thus can regulate food intake. There are many amino acid sensing receptors and transpor...
关键词：Amino acid sensing Gut hormones Sensing receptor Amino acid transporter Gut-brain signaling 
Synthesis and Structure Analysis of a Tripeptide Containing N-methyl Group Amino Acid被引量：2
《Chinese Journal of Structural Chemistry》2016年第5期718-724,共7页甄小丽 马振杰 田霞 李营 韩建荣 刘守信 
supported by the National Natural Science Foundation of China(No.21272052,21472034);Natural Science Foundation of Hebei Province(No.14272604D B2014208138);the Foundation of the Education Department of Hebei Province(No.ZH2012025,ZD2014017);National Basic Research Program of China(2011CB512007 and 2012CB723501)
A convenient method of synthesizing a tripeptide-containing N-methyl group amino acid was developed using O-benzotriazole-N,N,N＇,N＇-tetramethyluronium-hexafluorophosphate as the condensing agent. The crystals of tri...
关键词：tripeptide N-methyl amino acid synthesis crystal structure hydrogen bond 
Expression Pattern of Peptide and Amino Acid Genes in Digestive Tract of Transporter Juvenile Turbot(Scophthalmus maximus L.)被引量：3
《Journal of Ocean University of China》2016年第2期334-340,共7页XU Dandan HE Gen MAI Kangsen ZHOU Huihui XU Wei SONG Fei 
supported by the National Natural Science Foundation of China (No.31222055);973 Program (2014CB138602)
Turbot(Scophthalmus maximus L.),a carnivorous fish species with high dietary protein requirement,was chosen to examine the expression pattern of peptide and amino acid transporter genes along its digestive tract which...
关键词：TURBOT digestive tract amino acid PEPTIDE TRANSPORTER expression pattern 
N-phosphoryl amino acid models for P–N bonds in prebiotic chemical evolution被引量：4
《Science China Chemistry》2015年第3期374-382,共9页Feng Ni Chuan Fu Xiang Gao Yan Liu Pengxiang Xu Liu Liu Ye Lv Songsen Fu Ying Sun Daxiong Han Yan-Mei Li Yufen Zhao 
supported by the National Basic Research Program of China(2013CB910700,2012CB821600);the National Natural Science Foundation of China(21232005,21375113,21305115);the Program of Chinese Ministry of Education for Changjiang Scholars and Innovative Research Team in University
Post-translational modification of proteins by N-phosphorylation of the basic amino acid residues plays important roles in biological processes. The high-energy P–N bond might have contributed to the evolution of pre...
关键词：N-phosphoryl amino acid biological P–N bond chemical evolution origin of life 
Does the Genetic Code Have A Eukaryotic Origin?被引量：1
《Genomics, Proteomics & Bioinformatics》2013年第1期41-55,共15页Zhang Zhang Jun Yu 
supported by grants from the National Basic Research Program (973 Program) (Grant No. 2011CB944100and 2011CB944101);National Natural Science Foundation of China (Grant No. 90919024);the Special Foundation Work Program, the Ministry of Science and Technology (Grant No.2009FY120100);the "100-Talent Program" of Chinese Academy of Sciences (Grant No. Y1SLXb1365);the National Programs for High Technology Research and Development(863 Program;Grant No. 2012AA020409) by the Ministry of Science and Technology of China
In the RNA world, RNA is assumed to be the dominant macromolecule performing most, if not all, core ＂house-keeping＂ functions. The ribo-cell hypothesis suggests that the genetic code and the translation machinery ma...
关键词：Genetic code Purine content Sensitivity CODON Amino acid 
THERMOSENSITIVE POLYION COMPLEX MICELLES PREPARED BY SELF-ASSEMBLY OF TWO OPPOSITELY CHARGED DIBLOCK COPOLYMERS被引量：2
《Chinese Journal of Polymer Science》2013年第2期318-324,共7页Pan He Chang-wen Zhao Chun-sheng Xiao Zhao-hui Tang 陈学思 
financially supported by the National Natural Science Foundation of China (Nos. 20904053, 51021003,51173184);the Ministry of Science and Technology of China (International cooperation program 2011RI0001);the Program of the Science and Technology of Changchun (No. 2010061)
Polyion complex （PIC） micelles were spontaneously formed in aqueous solutions through electrostatic interaction between two oppositely charged block copolymers, poly（N-isopropylacrylamide）-b-poly（L-glutamic acid...
关键词：Polyion complex Micelles THERMOSENSITIVITY Poly（amino acid）s. 
Extensive Computational Study on Conformations of Microsolvated Leucine Complexes
《Chinese Journal of Chemical Physics》2012年第4期409-418,I0003,共11页刘莎 胡安东 林子敬 
V. ACKNOWLEDGMENTS This work was supported by the National Natural Science Foundation of China （No.11074233） the National Basic Research Program of China （No.2012CB215405）, and the Specialized Research Fund for the Doctoral Program of Higher Education （No.20113402110038）.
The conformations for leucine （Leu） hydrated with one to three water molecules, Leu-（H2O）n （n=1-3）, were carefully searched by considering the trial structures generated by all possible combinations of rotamers ...
关键词：Amino acid Hydration effect First principle calculation Potential energy surface IR spectrum 
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