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A plausible pathway to prebiotic peptides via amino acid amides on the primordial Earth: 《Earth and Planetary Physics》2024年第6期868-877,共10页DingWei Gan XiangMin Lei RenWu Zhou SongSen Fu Jing Sun RuSen Zhou Kostya(Ken)Ostrikov YuFen Zhao JianXi Ying; National Natural Science Foundation of China(Nos.42388101,92256203,and 42003062);Fundamental Research Funds for the Provincial Universities of Zhejiang(No.SJLY2023007);Technology and Engineering Center for Space Utilization,Chinese Academy of Sciences(No.YYWT-0901-EXP-16);Ningbo Top Talent Project(No.215-432094250).; The prebiotic synthesis of peptides prior to ribosome-catalyzed processes remains an enigma.The synthesis of abiotic peptides from amino acids(AAs)is primarily constrained by high activation energies and unfavorable t...; 关键词：prebiotic chemistry origin of life chemical evolution PEPTIDE

Advancing energy storage with nitrogen containing biomaterials utilizing amino acid, peptide and protein: Current trends and future directions: 《Journal of Energy Chemistry》2024年第12期253-276,共24页Madan R.Biradar Harshad A.Mirgane Sidhanath V.Bhosale Sheshanath V.Bhosale; financial support from The Director, CSIR-IICT (MS No. IICT/Pubs./2024/043) Hyderabad, India;University Grant Commission (UGC) Faculty Research Program, New Delhi, India (F.4-5(50-FRP) (IV-Cycle)/2017(BSR)) for an award of Professorship。; As the climate crisis continues to escalate, there has been a growing emphasis on the development of electrode materials that are environmentally friendly and sustainable. Biomolecules, such as proteins,peptides, and ...; 关键词：Amino acid Battery Electrolytes PEPTIDE PROTEIN SUPERCAPACITOR Fuel cell

Decreased Amino Acid Transporter LAT2 Is the Main Determinant of Impaired Protein Utilization During Aging: 《Engineering》2024年第11期88-98,共11页Rui Song Guang Li Liang Zhao Lili Qiu Xiyu Qin Xiaoxu Zhang Xiaoxue Liu Jun Zhou Mengxiao Hu Liwei Zhang Jiaqi Su Xinjuan Liu Xiaoyu Wang; funded by the National Key Research and Development Program of China(2023YFF1104502);the Young Elite Scientists Sponsorship Program by China Association for Science and Technology(2022QNRC001).; As the global demographic shifts toward an aging population,understanding the efficiency of protein uti-lization in older adults becomes crucial.Our study explores the intricate relationship between protein intake and...; 关键词：AGING Protein utilization PEPTIDE Amino acid Large neutral amino acid transporter 2

α,β-Dehydroamino Acid Synthesis through Proline-Catalyzed Aldol Condensation with a Glycine Schiff Base: 《Precision Chemistry》2024年第1期14-20,共7页Jun Sawamura Daikan Ieiri Ryo Yazaki Takashi Ohshima; supported by MEXT KAKENHI grant numbers JP21A204,JP21H05207,and JP21H05208 for The Grant-in-Aid for Transformative Research Areas(A)Digitalization-driven Transformative Organic Synthesis(Digi-TOS)from MEXT,a Grant-in-Aid for Scientific Research(B)(JP21H02607);the JST-FOREST program(JPMJFR2229);a Grant-in-Aid for Basis for Supporting Innovative Drug Discovery and Life Science Research(BINDS)(JP20am0101091,JP22ama121031)and AMED(JP21ak0101167,JP22ak0101167,JP23ak0101167);J.S.thanks the Japan Science and Technology Agency(JST)SPRING(JPMJSP2136).; A general protocol for the synthesis ofα,β-dehydroamino acids and their peptides was developed.Proline efficiently catalyzed an aldol condensation reaction of a glycine Schiff base with a variety of aldehydes.The hy...; 关键词：α β-dehydroamino acid PEPTIDE PROLINE aldol condensation glycine Schiff base transimination

Postassembly Modifications of Peptides via Metal-Catalyzed C–H Functionalization被引量：4: 《CCS Chemistry》2021年第3期1797-1820,共24页Hua-Rong Tong Bo Li Guoxing Li Gang He Gong Chen; The authors acknowledge the Natural Science Foundation of China(nos.91753124 and 21725204) financial support of this work.; The growing importance of peptides and proteins in therapeutic and biomedical applications has provided immense motivation toward the development of new ways to construct and transform peptide molecules.As in other ar...; 关键词：PEPTIDES metal catalysis C–H functionalization peptide modification amino acid

Chemical Synthesis of Proteins Containing 300 Amino Acids被引量：4: 《Chemical Research in Chinese Universities》2020年第5期733-747,共15页ZHANG Baochang LI Yulei SHI Weiwei WANG Tongyue ZHANG Feng LIU Lei; Supported by the National Key R&D Program of China(No.2017YFA0505200);the National Natural Science Foundation of China(Nos.21532004,91753205,81621002).; Chemical synthesis of proteins containing up to 300 amino acids may cover 30%—50%of all the proteins encountered in biomedical studies and may provide an alternate approach to the usually used recombinant expression ...; 关键词：Chemical protein synthesis Solid-phase synthesis PEPTIDE LIGATION 300 amino acid

Facilitating the acceptance of tangibly reduced-crude protein diets for chicken-meat production被引量：8: 《Animal Nutrition》2020年第3期247-257,共11页Peter V.Chrystal Shiva Greenhalgh Peter H.Selle Sonia Yun Liu; Inclusions of non-bound amino acids particularly methionine,lysine and threonine,together with the"ideal protein"concept have allowed nutritionists to formulate broiler diets with reduced crude protein(CP)and increase...; 关键词：Amino acid Dietary energy Digestive dynamic Electrolyte balance PEPTIDE Reduced crude protein

Synthesis of the arsenic-containing amino-acids, and their potential applications in peptide chemistry: 《Journal of Chinese Pharmaceutical Sciences》2017年第5期372-378,共7页石亚娟管清华吴艳芬王超; Trivalent organoarsenic compounds have attracted a great deal of interest because of their potential antineoplastic activities. In this work, we synthesized a series of arsenic-containing amino acid analogues by intro...; 关键词：Organoarsenic compound Amino acid Peptide chemistry

The reactive activities of natural amino acids: key principles of peptide-templated Au cluster synthesis被引量：1: 《Science Bulletin》2016年第22期1732-1738,共7页Xu Li Nan Li Lina Zhao; supported by the National Key Basic Research Program of China (2013CB932703, 2013CB933704);the National Natural Science Foundation of China (11404333, 31571026);the Special Program for Applied Research on Super Computation of the NSFC-Guangdong Joint Fund (the second phase); Coating of gold nanoclusters with peptides is an important targeting method in biomedical applications.However, their synthetic method highly influences their targeting ability. Current methods often use harsh reagent...; 关键词：Reactive activity Amino acid Synthesis in situ Au nanocluster DFT calculation

Expression Pattern of Peptide and Amino Acid Genes in Digestive Tract of Transporter Juvenile Turbot(Scophthalmus maximus L.)被引量：3: 《Journal of Ocean University of China》2016年第2期334-340,共7页XU Dandan HE Gen MAI Kangsen ZHOU Huihui XU Wei SONG Fei; supported by the National Natural Science Foundation of China (No.31222055);973 Program (2014CB138602); Turbot(Scophthalmus maximus L.),a carnivorous fish species with high dietary protein requirement,was chosen to examine the expression pattern of peptide and amino acid transporter genes along its digestive tract which...; 关键词：TURBOT digestive tract amino acid PEPTIDE TRANSPORTER expression pattern

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