云南高校图书馆联盟文献共享服务平台- ANNEXIN

ANNEXIN: 作品数：397被引量：1087H指数：13; 导出分析报告; 相关领域：医药卫生更多>>; 相关作者：姚兵阮长耿江淼孙树汉李道明更多>>; 相关机构：苏州大学大连医科大学中南大学第二军医大学更多>>; 相关期刊：更多>>; 相关基金：国家自然科学基金国家高技术研究发展计划国家重点基础研究发展计划广东省自然科学基金更多>>

A novel annexin dimer targets microglial phagocytosis of astrocytes to protect the brain-blood barrier after cerebral ischemia: 《Acta Pharmacologica Sinica》2025年第4期852-866,共15页Wei Tang Rong Cheng Meng-yue Gao Min-jin Hu Lu Zhang Qiang Wang Xin-yu Li Wei Yan Xiao-ying Wang Hai-mei Yang Jian Cheng Zi-chun Hua; supported by the National Natural Science Foundation of China(82071469,32271033);the Priority Academic Program Development of the Jiangsu Higher Education Institutions(PAPD);Jiangsu Department of Science and Technology(BK20230164,BK20230165,BE2023695,BK20231136 and BK20243001);Changzhou Municipal Department of Science and Technology(2022169,CJ2023001,CJ20220019,and CJ20235009);the Suzhou Clinical Research Center of Neurological Disease(Szzx201503)and the Jiangsu Key Laboratory Grant(BM2013003).; Despite the vital role of astrocytes in preserving blood-brain barrier(BBB)integrity,their therapeutic potential as targets in ischemic stroke-induced barrier disruption remains underexplored.We previously reported ex...; 关键词：cerebral ischemia blood-brain barrier ASTROCYTES PHOSPHATIDYLSERINE Annexin A5

颈动脉超声参数及血清膜联蛋白A2水平与冠心病患者冠状动脉狭窄程度的相关性分析及临床意义: 《黑龙江医药科学》2025年第1期110-113,共4页侯琼崔存英黄丹青; 河南省医学科技攻关联合共建项目,编号:LHGJ20217841。; 目的:探讨冠心病患者血清膜联蛋白A2(ANXA2)、颈动脉超声参数水平与冠状动脉狭窄程度的相关性,并分析其临床意义。方法:回顾性选取2021年7月至2024年2月新郑华信民生医院104例冠心病患者为研究对象,根据冠状动脉狭窄程度分为轻度狭窄组(...; 关键词：颈动脉超声参数 AnnexinⅡ 冠心病冠状动脉狭窄

冠状动脉支架植入术病人血清MMP-3、AnnexinⅡ水平及其与术后再狭窄的相关性: 《中西医结合心脑血管病杂志》2024年第20期3776-3780,共5页夏文君卢嘉成; 河北省中医药管理局资助项目(No.2021391)。; 目的:分析冠状动脉支架植入术病人血清基质金属蛋白酶-3(MMP-3)、膜联蛋白A2(AnnexinⅡ)水平及其与术后再狭窄的相关性。方法:选取唐山市中医医院2019年10月—2021年10月行冠状动脉支架植入术的102例病人。术后随访1年,依据术后再狭窄...; 关键词：冠状动脉支架植入术支架内再狭窄基质金属蛋白酶-3 膜联蛋白A2

Study on the anti-inflammatory mechanism of moxibustion in rheumatoid arthritis in rats based on phospholipaseA2 signaling inhibition by Annexin 1: 《Journal of Traditional Chinese Medicine》2024年第4期753-761,共9页GUO Yanding LUO Kun ZHANG Linlin LU Wenting SHANG Yanan ZHONG Yumei HU Danhui YANG Xin ZHOU Haiyan; Grants from the National Natural Science Foundation of China:Study on the Immune Mechanism of Macrophages 1/Macrophages 2 Polarization of Macrophages Treated with Moxibustion"Strengthening the Body and Expelling Pathogenic Qi"for"Struggle Between Healthy Qi and Pathogenic Qi"in Rheumatoid Arthritis(No.81973959);the National Key R&D Program of China:a Comparative Study of Moxibustion at Zusanli(ST36)on the Polarization of Knee Synovial Macrophage in Kneeosteoar-thritis and Rheumatoid Arthritis Rat Models(No.2019YFC1709001);the National Natural Science Foundation of China:Study on the Regulatory Mechanism of the"Immune-Inflammation"Molecular Signal of the Nucleotide—Binding Oligomerization Domain,Leucine rich Repeat and Pyrin domain containing Proteins 3 Inflammasome Treated by Moxibustion for Rheumatoid Arthritis(No.81774435);the Foundation of Chengdu University of Traditional Chinese Medicine:Study on the Mechanism of"Macrophage Migration Inhibitory Factor-Target Protein-Glucocorticoid-Inflammation"in Moxibustion Treatment and Anti-inflammatory Effect of Rheumatoid Arthritis(No.QNXZ2018034);the Science and Technology Innovation Seedling Project of Sichuan Province:Exploring the Effector Mechanism of Moxibustion Treatment in the Experimental Rheumatoid Arthritis Model based on the Macrophage Macrophages 1 Polarization Signaling Pathway Toll-like Receptors 4-Maximum Tolerated Dose 88-Nuclear Factor-Kappa B and its Regulatory Molecule T Cell Immunoglobulin and Mucin Domain-containing Protein 3(No.2022037)。; OBJECTIVE:To determine whether moxibustion had an anti-inflammatory effect on rheumatoid arthritis(RA)by regulating Annexin 1 expression and interfering with the phospholipaseA2 signaling pathway.METHODS:Thirty male S...; 关键词：ANNEXINS group IV phospholipases A2 signal transduction MOXIBUSTION arthritis rheumatoid

Knockdown Annexin A8 inhibits the proliferation and invasion of cervical cancer cells: 《BIOCELL》2023年第12期2697-2708,共12页WEILING ZHANG YONG LI CAN ZHANG QING HAN YU ZHANG AIQIN HE WEIPEI ZHU; supported by the project in Nantong Health and Family Planning Commission(MS2022045).; This study aimed to explore the expression,function,and molecular mechanism of ANXA8,the gene for annexin 8,in cervical cancer.Methods:The gene expression of the ANX family members in cervical cancer tissues was class...; 关键词：Cervical cancer MARKER Molecular mechanisms

血清Annexin Ⅱ、CRP及H-FABP水平预测冠心病合并房颤患者发生主要不良心脏事件的价值被引量：1: 《中国实用医刊》2023年第19期5-8,共4页张建建康杰; 目的探讨血清膜联蛋白A2(AnnexinⅡ)、C反应蛋白(CRP)及心脏型脂肪酸结合蛋白(H-FABP)预测冠心病合并房颤患者发生主要不良心脏事件(MACE)的价值。方法抽取2018年6月至2021年6月济南市第二人民医院收治的冠心病合并房颤患者186例,对患...; 关键词：冠心病房颤膜联蛋白A2 C反应蛋白心脏型脂肪酸结合蛋白

老年冠心病患者血清cathepsin S、Chemerin、AnnexinⅡ变化及临床意义: 《实验与检验医学》2023年第4期421-424,共4页苗文涛马果果张烨李留阳吴苑苑; 目的探讨老年冠心病(CHD)患者血清血清组织蛋白酶S(Cathepsin S)、血清趋化素(Chemerin)、膜联蛋白Ⅱ(AnnexinⅡ)变化及临床意义。方法选取2020年4月至2021年4月在本院确诊的98例CHD患者作为CHD组,根据患者检出病变最严重血管狭窄程度...; 关键词：冠心病组织蛋白酶S 血清趋化素膜联蛋白Ⅱ

白杨素通过下调Annexin A3逆转人肺腺癌A549/DDP细胞顺铂的耐药性: 《贵州医科大学学报》2023年第7期800-806,共7页刘晖杰彭荣许华; 湖北省自然科学基金(WJ2019M132)。; 目的观察白杨素对肺腺癌顺铂(DDP)耐药性细胞A549/DDP耐药敏感性的影响。方法取A549和A549/DDP细胞,qRT-PCR及Western blot法检测膜联蛋白A3(Annexin A3)基因及蛋白表达,CCK-8法测不同浓度白杨素(0、5、25、50、100 mmoL/L)干预后细胞...; 关键词：肺腺肿瘤白杨素膜联蛋白A3 顺铂耐药 A549/DDP细胞

AnnexinⅠ、p53及PTEN在子宫内膜样腺癌中的表达及其临床意义: 《川北医学院学报》2023年第5期590-594,共5页杨昕高云孙振柱; 新疆维吾尔自治区自然科学基金资助项目(2016D01C153)。; 目的:探究钙磷脂结合蛋白(AX-Ⅰ)、p53及PTEN在子宫内膜样腺癌(EEC)发生发展过程中的表达及其临床意义。方法:应用免疫组织化学法检测AX-Ⅰ、p53及PTEN在27例子宫内膜良性增生(BH组)、42例子宫内膜非典型增生(ATH组)及53例子宫内膜样腺...; 关键词：钙磷脂结合蛋白 P53 PTEN 非典型增生子宫内膜样腺癌

Discovery of a first-in-class ANXA3 degrader for the treatment of triple-negative breast cancer被引量：1: 《Acta Pharmaceutica Sinica B》2023年第4期1686-1698,共13页Yongxi Liang Delin Min Hulin Fan Kunlin Liu Juchuanli Tu Xueyan He Bingjie Liu Lu Zhou Suling Liu Xun Sun; supported by the National Natural Science Foundation of China(Nos.82073688,82103971 and 81930075);Shanghai Science and Technology Development Fund from Central Leading Local Government(No.YDZX20223100001004,China);Science and Technology Commission of Shanghai Municipality(No.21S11907300,China);Program of Shanghai Academic/Technology Research Leader(No.20XD1400700,China)。; Triple-negative breast cancer(TNBC)is a nasty disease with extremely high malignancy and poor prognosis.Annexin A3(ANXA3)is a potential prognosis biomarker,displaying an excellent correlation of ANXA3 overexpression w...; 关键词：Annexin A3(ANXA3) Degrader Triple-negative breast cancer UBIQUITINATION Patient-derived xenograft

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