云南高校图书馆联盟文献共享服务平台- ARPE-19

ARPE-19: 作品数：77被引量：169H指数：6; 导出分析报告; 相关领域：医药卫生更多>>; 相关作者：袁志兰王斌庄曾渊梁丽娜刘海燕更多>>; 相关机构：南京医科大学江苏省人民医院中国中医科学院眼科医院青岛大学更多>>; 相关期刊：《中南药学》《Advances in Bioscience and Biotechnology》《工业微生物》《联勤军事医学》更多>>; 相关基金：国家自然科学基金中央级公益性科研院所基本科研业务费专项南京医科大学校科研和教改项目广东省科技计划工业攻关项目更多>>

基于Nrf2/HO-1/GPX4信号通路探讨葫芦巴碱对ARPE-19铁死亡的干预研究: 《国际眼科杂志》2025年第2期191-197,共7页岳欣欣付洋金海哲尹晓燕傅全威; 国家自然科学基金项目(No.72171042);辽宁省教育厅高校项目(No.LJKMZ20221981)。; 目的:基于Nrf2/HO-1/GPX4途径探讨和阐明葫芦巴碱(TRG)保护人视网膜色素上皮(ARPE-19)铁死亡的干预机制。方法:用不同浓度的葫芦巴碱干预ARPE-19细胞筛选葫芦巴碱干预ARPE-19细胞的最佳浓度,随后进行分组(NC组、HG组、Fer-1组、TRG组),...; 关键词：葫芦巴碱铁死亡核因子E2相关因子2(Nrf2) 血红素加氧酶-1(HO-1) 谷胱甘肽过氧化物酶4(GPX4) 氧化应激糖尿病视网膜病变人视网膜色素上皮(ARPE-19)

Inhibition of RhoA/Rho-kinase pathway suppresses the expression of extracellular matrix induced by CTGF or TGF-β in ARPE-19: 《International Journal of Ophthalmology(English edition)》2025年第2期322-322,共1页Jing Zhu Duy Nguyen Hong Ouyang Xiao-Hui Zhang Xiao-Ming Chen Kang Zhang; We ourselves recently reviewed our article published in Int J Ophthalmol entitled“Inhibition of RhoA/Rho-kinase pathway suppresses the expression of extracellular matrix induced by CTGF or TGF-βin ARPE-19”and would...; 关键词：submit Ophthal matrix

Autophagy serves as a protective effect against inflammatory injury of oxidative stress in ARPE-19 cell: 《International Journal of Ophthalmology(English edition)》2025年第1期28-38,共11页Na-Na Meng Lei-Zhou Xia Yi-Qing Gong Pei-Rong Lu; Supported by the Science and Technology Planning Social Development Project of Zhenjiang City(No.FZ2022132,No.FZ2023062,No.SH2023041);Foundation of Jinshan Doctor of Zhenjiang City(No.2021-JSYZ-13);Foundation of the Affiliated People’s Hospital of Jiangsu University(No.KFB2020005,No.KFQM-08).; AIM:To test the effect of autophagy on inflammatory damage resulting from oxidative stress in adult retinal pigment epithelial cell line(ARPE-19).METHODS:ARPE-19 cells were pretreated with 200 and 600μmol/L hydrogen ...; 关键词：retinal pigment epithelium AUTOPHAGY reactive oxygen species INFLAMMATION

根皮素包合物对ARPE-19细胞损伤的保护效果的研究: 《工业微生物》2024年第6期75-81,共7页郭志想杨光杨波王凯; 为探究根皮素(Phloretin,Ph)及根皮素/羟丙基-β-环糊精包合物(Ph/HBC-IC)对甲基乙二醛(MGO)诱导的人视网膜色素上皮细胞(ARPE-19)损伤的保护效果,文章采用冷冻干燥法制备得到Ph/HBC-IC,并利用傅里叶红外光谱(FTIR)、扫描电镜(SEM)、X...; 关键词：根皮素包合物甲基乙二醛人视网膜上皮细胞(ARPE-19) 保护效果

黑色素代谢途径在香叶木素改善紫外诱导的ARPE-19细胞损伤中的保护作用: 《中国药理学通报》2024年第11期2061-2068,共8页马绍壮冀欣业张晏源张波; 国家自然科学基金资助项目(No U1603122);四川省天府峨眉创新领军人才项目(No 1811)。; 目的探讨香叶木素对年龄相关性黄斑变性(age-related macular degeneration,AMD)保护作用及机制。方法基于GEO数据库分析AMD与正常病例样本视网膜色素上皮(retinal pigment epithelial,RPE)细胞差异表达基因。建立302 nm紫外线B(ultravi...; 关键词：年龄相关性黄斑变性紫外光损伤香叶木素黑色素酪氨酸酶生物信息学分析

Effect of acetyl L-carnitine on human retinal pigment epithelium-19 cells in hypoxic conditions: 《国际眼科杂志》2024年第10期1515-1521,共7页Ali Dal Onur Catak Murat Erdag Mehmet Canleblebici Ebru Onalan Ilay Buran; Firat大学科研中心项目(No.TF:19.41)。; AIM:To investigate the effect of acetyl-L-carnitine(ALCAR)on cell viability,morphological integrity,and vascular endothelial growth factor(VEGF)expression in human retinal pigment epithelium(ARPE-19)cells using a hypo...; 关键词：acetyl-L-carnitine(ALCAR) human retinal pigment epithelium(ARPE-19) vascular endothelial growth factor(VEGF) hypoxia-inducible factor 1(HIF-1α)

A Novel and Functional Artificial Bruch’s Membrane Made of Poly (ε-Caprolactone)/Gelatin for Retinal Pigment Epithelium Restoration: 《Advances in Bioscience and Biotechnology》2024年第8期443-461,共19页López Edith Silva-Bermudez Phaedra Gonzalez-Salinas Roberto Velasquillo Cristina Torres-Romero Abigail López-Colomé Ana María Pérez Armando Gina Prado-Prone Edgar Ramos-Martínez Iván Ramos-Martínez Quiroz-Mercado Hugo Hernández-Zimbrón Luis Fernando; Purpose: The primary aim of this paper is to design, create, and improve functional and artificial Bruch’s membranes (BM) using bioengineering techniques, which can be applied in the treatment of maculopathies by sup...; 关键词：Artificial Bruch’s Membrane ELECTROSPINNING ARPE-19 Cells Age-Related Macular Degeneration

红景天苷脂质体的构建及其对高糖诱导ARPE-19细胞氧化损伤的保护作用被引量：1: 《中南药学》2024年第6期1435-1440,共6页丁文华汪凯康贾文刘家佳高家荣徐维平; 国家自然科学基金项目(No.52072360)。; 目的构建红景天苷脂质体(SAL-LIPS),对其进行评价,并研究SAL-LIPS在高糖(HG)环境下对人视网膜色素上皮(ARPE-19)细胞氧化损伤的保护作用。方法采用乙醇注入法制备SAL-LIPS,通过透射电镜观察其形态,测定粒径、多分散系数(PDI)并考察制...; 关键词：红景天苷脂质体 ARPE-19 抗氧化

非接触共培养体系下抑制ARPE-19中CAMKⅡ表达对HUVECs迁移和侵袭及管腔形成的影响: 《国际眼科杂志》2024年第4期508-514,共7页徐卫星刘华张岩; 目的:探讨非接触共培养体系下抑制人视网膜色素上皮细胞(ARPE)中Ca2+/钙调蛋白依赖性蛋白激酶Ⅱ(CAMKⅡ)表达对人脐静脉内皮细胞(HUVECs)迁移、侵袭、管腔形成的影响。方法:将过表达CAMKⅡ-δ的ARPE-19样本进行RNA测序,应用生物信息学...; 关键词：Ca^(2+)/钙调蛋白依赖性蛋白激酶Ⅱ(CAMKⅡ) 自生肽2相关抑制肽(AIP) 迁移人视网膜色素上皮细胞(ARPE) 人脐静脉内皮细胞(HUVECs)

Protective effect of Liangxue Huayu decoction on human retinal pigment epithelial cell(ARPE-19)injury induced by hypoxia through autophagy pathway: 《Pharmacology Discovery》2024年第1期44-50,共7页Han-Ran Zheng Yi-Tong Lin Sheng Chen Zi-Yang Chen Jun-Chang Cao Zhao-Da Ye Yan-Hong Hu; support of the foundation projects:Fujian Province Traditional Chinese Medicine Research Project Plan(No.2021ZYJC08).; Background:Exploring the protective mechanism of the Liangxue Huayu(LXHY)decoction on human retinal pigment epithelial(RPE)cells induced by hypoxia through the autophagy pathway.Methods:The appropriate LXHY decoction ...; 关键词：Liangxue Huayu decoction age-related macular degeneration AUTOPHAGY LYSOSOME AUTOPHAGOSOMES

ARPE-19