BATROXOBIN

作品数：32被引量：81H指数：5
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相关领域：医药卫生更多>>
相关作者：姜志胜符民桂唐朝枢夏春芳刘乃奎更多>>
相关机构：北京医科大学江苏省人民医院宁波市第二医院广州医学院更多>>
相关期刊：《现代预防医学》《Journal of Hainan Medical University》《蛇志》《中国药理学通报》更多>>
相关基金：国家自然科学基金四川省教育厅科学研究项目中国博士后科学基金更多>>
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Protective effects of Batroxobin on spinal cord injury in rats被引量：11
《Neuroscience Bulletin》2013年第4期501-508,共8页Hong Fan Xia Liu Hai-Bin Tang Peng Xiao Ya-Zhou Wang Gong Ju 
supported by grants from the National Natural Science Foundation of China (81072600 and 31271583)
Expansion of the secondary injury following primary spinal cord injury is a major pathological event that increases destruction in the spinal cord, so measures to reduce secondary injury are needed. Our previous study...
关键词：spinal cord injury secondary injury FIBRINOGEN BATROXOBIN 
GAP-43 Expression and Pathological Changes of Temporal Infarction in R.ats and Effects of Batroxobin被引量：4
《Journal of Traditional Chinese Medicine》2002年第1期42-46,共5页吴卫平 管兴志 匡培根 张小澍 
To study the changes of the expression of growth-associated protein-43 (GAP-43) and pathology in temporal infarction of rats photochemically induced and the effects of batroxobin. METHODS: Immunohistochemical techniqu...
关键词：Animals BATROXOBIN Brain Infarction Fibrinolytic Agents GAP-43 Protein Male NEOCORTEX Random Allocation RATS Rats  Wistar Temporal Lobe 
Effect of Batroxobin on Expression of Neural Cell Adhesion Molecule in Temporal Infarction Rats and Spatial Learning and Memory Disorder被引量：4
《Journal of Traditional Chinese Medicine》2001年第4期294-298,共5页吴卫平 管兴志 匡培根 姜树军 扬炯炯 隋南 AlbertChen 匡培梓 张小澍 
The effect of Batroxobin expression of neural cell adhesion molecule (NCAM) in left temporal ischemic rats with spatial memory disorder was investigated by means of Morri's water maze and immunohistochemical methods. ...
关键词：Animals BATROXOBIN Cell Adhesion Molecules  Neuronal Cerebral Infarction Male Maze Learning Memory Disorders Neuroprotective Agents Random Allocation RATS Rats  Wistar Temporal Lobe 
Batroxobin Against Anoxic Damage of Rat Hippocampal Neurons in Culture:Morphological Changes and Hsp70 Expression
《Journal of Traditional Chinese Medicine》2001年第3期215-219,共5页刘军 匡培根 吴卫平 王福庄 丁爱石 
军队"十五"攻关项目01MB077
Batroxobin,the thrombin-like enzyme,is used for therapeutic defibrination. We have found that batroxobin has good therapeutic effect in ischemic reperfusion rats and clinical practices in vivo. But we have not studied...
关键词：ANIMALS Animals  Newborn BATROXOBIN Cell Hypoxia Cell Survival Cells  Cultured HSP70 Heat-Shock Proteins Hippocampus Neurons Neuroprotective Agents RATS Rats  Wistar 
Effect of Batroxobin on Neuronal Apoptosis During Focal Cerebral Ischemia and Reperfusion in Rats被引量：3
《Journal of Traditional Chinese Medicine》2001年第2期136-140,共5页吴卫平 匡培根 李振洲 
We have found that Batroxobin plays a protective role in ischemic brain injury, which attracted us to investigate the effect of Batroxobin on apoptosis of neurons during cerebral ischemia and reperfusion. The apoptoti...
关键词：ANIMALS Apoptosis BATROXOBIN Brain Ischemia Male NEURONS Neuroprotective Agents Random Allocation RATS Rats  Sprague-Dawley Reperfusion Injury 
Metabolic Changes in Rats with Photochemically Induced Cerebral Infarction and the Effects of Batroxobin:A Study by Magnetic Resonance Imaging,~1H-and ^(31)p-Magnetic Resonance Spectroscopy被引量：6
《Journal of Traditional Chinese Medicine》2001年第1期59-67,共9页管兴志 吴卫平 匡培根 匡培梓 高杨 管林初 李丽云 毛希安 刘买利 
Metabolic changes in rats with photochemically induced cerebral infarction and the effects of batroxobin were investigated 1, 3, 5 and 7 days after infarction by means of magnetic resonance imaging (MRI), 1H- and 31P-...
关键词：Animals Aspartic Acid BATROXOBIN Cerebral Infarction Magnetic Resonance Imaging Male PHOTOCHEMISTRY Photosensitizing Agents Random Allocation RATS Rats  Sprague-Dawley Rose Bengal 
Effects of Batroxobin on Spatial Learning and Memory Disorder of Rats with Temporal Ischemia and the Expression of HSP32 and HSP70被引量：3
《Journal of Traditional Chinese Medicine》2000年第4期297-301,共5页吴卫平 匡培根 姜树军 张小澍 杨炯炯 隋南 Albert Chen 匡培梓 
　　The effect of Batroxobin on spatial memory disorder of left temporal ischemic rats and the expression of HSP32 and HSP70 were investigated with Morri`s water maze and immunohistochemistry methods. The results show...
关键词：OXYGENASES Animals BATROXOBIN Brain Ischemia DOWN-REGULATION HSP70 Heat-Shock Proteins Heat-Shock Proteins Heme Oxygenase (Decyclizing) Learning Disorders Male Maze Learning Memory Disorders Random Allocation RATS Rats  Wistar Snake Venoms Spatial Behavior Temporal Lobe 
Effect of Batroxobin on Expression of C-Jun in Left Temporal Ischemic Rats with Spatial Learning and Memory Disorder
《Journal of Traditional Chinese Medicine》2000年第2期147-151,共5页吴卫平 匡培根 姜树军 扬炯炯 隋南 匡培梓 张小澍 
The effect of Batroxobin on expression of c-Jun in left temporal ischemic rats with spatial memory disorder was investigated by means of Morri's water maze and immunohistochemistry methods. The results showed that the...
关键词：Genes  jun Animals BATROXOBIN Gene Expression Hypoxia-Ischemia  Brain Male Memory Disorders Proto-Oncogene Proteins c-jun Random Allocation RATS Rats  Wistar Temporal Lobe 
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