supported by the National Natural Science Foundation of China(Grant Nos.82074277,8177391);the Basic Research Cooperation Project of Beijing,Tianjin,Hebei from the Natural Science Foundation of Tianjin(Grant Nos.20JCZXJC00070 and J200018);the Young Elite Scientists Sponsorship Program of Tianjin(Grant No.TJSQNTJ-2017-14).
Many scientific efforts have been made to penetrate the blood-brain barrier and target glioblastoma cells,but the outcomes have been limited.More attention should be given to local inhibition of recurrence after gliob...
Objective To screen the differential proteins in the brain(neocortex and hippocampus)between the rats with cortical dysplasia(CD)and control ones,and investigate the role of their alteration in the development of epil...
supported by grants(2010CB945500,2012CB966300,2009CB941100,81271003) from National Nature Science Foundation,Ministry of Science and Technology of China
Objective:To investigate the effects of BCNU/PLGA microspheres on tumor growth,apoptosis and chemotherapy resistance in a C57BL/6 mice orthotopic brain glioma model using GL261 cell line.Methods:BCNU/PLGA sustained-...
It had been found that interleukin-8 (IL-8) was associated with drug resistance. We previously demonstrated that the resistance to 1, 3-bis (2-chloroethyl)-1-nitrosourea (BCNU) of glioma cell line SWOZI was much...