CASSETTE

作品数：57被引量：230H指数：9
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Clinical Value of ABCB1 and PAI-1 Gene Polymorphisms in Predicting Glucocorticoid-induced Adverse Reactions in Nephrotic Syndrome Patients
《Current Medical Science》2024年第5期923-931,共9页Ya-ling ZHAI Shuai-gang SUN Wen-hui ZHANG Hui-juan TIAN Zhan-zheng ZHAO 
supported by the General Project of Henan Natural Science Foundation(No.232300420034);the National Natural Science Foundation of China for the Youth(No.81600555);the General Project of China Postdoctoral Science Foundation(No.2018M640684)。
Objective Glucocorticoid(GC)-induced adverse reactions(ARs)have been extensively studied due to their potential impact on patients’health.This study aimed to examine the potential correlation between two polymorphism...
关键词：adenosine triphosphate-binding cassette B1 nephrotic syndrome plasminogen activator inhibitor-1 steroid-associated avascular necrosis of the femoral head steroid diabetes 
Characteristics of staphylococcal cassette chromosome mec and lugdunin operon genes in the complete genome of Staphylococcus lugdunensis
《Chinese Medical Journal》2023年第11期1367-1369,共3页Shining Fu Yusheng Chen Ke Hu Tian Qin Yukun He Lili Zhao Xinqian Ma Li Chen Wenyi Yu Yan Yu Yu Xie Yifan Wang Donghong Yang Yu Xu Zhancheng Gao 
National Science and Technology Major Project of China(No.2017ZX10103004-006);National Key Research and Development Programme of China(No.2016YFC0903800)
Staphylococcus lugdunensis(S.lugdunensis)is a coagulase-negative Staphylococcus comprising the normal skin microbiota,primarily colonizing the lower abdomen and extremities.[1]S.lugdunensis has attracted substantial a...
关键词：MEC primarily ABDOMEN 
Double knock-in pig models with elements of binary Tet-On and phiC31 integrase systems for controllable and switchable gene expression被引量：5
《Science China(Life Sciences)》2022年第11期2269-2286,共18页Qin Jin Xiaoyu Yang Shixue Gou Xiaoyi Liu Zhenpeng Zhuang Yanhui Liang Hui Shi Jiayuan Huang Han Wu Yu Zhao Zhen Ouyang Quanjun Zhang Zhaoming Liu Fangbing Chen Weikai Ge Jingke Xie Nan Li Chengdan Lai Xiaozhu Zhao Jiaowei Wang Meng Lian Lei Li Longquan Quan Yinghua Ye Liangxue Lai Kepin Wang 
the National Key Research and Development Program of China(2017YFA0105103,2021YFA0805903);the National Natural Science Foundation of China(81941004,32170542);2020 Research Program of Sanya Yazhou Bay Science and Technology City(202002011);Major Science and Technology Projects of Hainan Province(ZDKJ2021030);Key Research&Development Program of Hainan Province(ZDYF2021SHFZ052);Youth Innovation Promotion Association of the Chinese Academy of Sciences(2019347);Young Elite Scientist Sponsorship Program by CAST(YESS20200024);Biological Resources Progaramme,Chinese Academy of Sciences(KFJBRP-017-57);Key Research&Development Program of Bioland Laboratory(Guangzhou Regenerative Medicine and Health Guangdong Laboratory)(2018GZR110104004);China Postdoctoral Science Foundation(2020M682943);Science and Technology Planning Project of Guangdong Province,China(2019A030317010,2020B1212060052,2021B1212040016,2021A1515011110);Science and Technology Program of Guangzhou,China(202007030003);Research Unit of Generation of Large Animal Disease Models,Chinese Academy of Medical Sciences(2019-I2M-5-025)。
Inducible expression systems are indispensable for precise regulation and in-depth analysis of biological process.Binary Tet-On system has been widely employed to regulate transgenic expression by doxycycline.Previous...
关键词：double knock-in Tet-On system phiC31-mediated cassette exchange pig model hKRASG12D-related tumorigenesis 
Characterization of Photorhabdus Virulence Cassette as a causative agent in the emerging pathogen Photorhabdus asymbiotica
《Science China(Life Sciences)》2022年第3期618-630,共13页Xia Wang Jiaxuan Cheng Jiawei Shen Liguo Liu Ningning Li Ning Gao Feng Jiang Qi Jin 
supported by the National Natural Science Foundation of China(31870108,32070081,32000080,31725007,31630087,and 31922036);the Beijing Natural Science Foundation(5192019);the CAMS Innovation Fund for Medical Sciences(2016-I2M-1013);the Non-profit Central Institute Fund of Chinese Academy of Medical Sciences(2017PT31049,2018PT51009,and 2018PT31012);the National Key Research and Development Program of China(2019YFA0508904);supported by High-performance Computing Platform of Peking University。
The extracellular contractile injection systems(e CISs)are encoded in the genomes of a large number of bacteria and archaea.We have previously characterized the overall structure of Photorhabdus Virulence Cassette(PVC...
关键词：Photorhabdus asymbiotica PVC cryo-electron microscopy EFFECTOR PYROPHOSPHATASE 
Enhanced production of poly-γ-glutamic acid via optimizing the expression cassette of Vitreoscilla hemoglobin in Bacillus licheniformis被引量：4
《Synthetic and Systems Biotechnology》2022年第1期567-573,共7页Qing Zhang Yaozhong Chen Lin Gao Jian’gang Chen Xin Ma Dongbo Cai Dong Wang Shouwen Chen 
the National Natural Science Foundation of China(31972849);National Key Research and Development Program of China(2021YFC2101700);the Science and Technology Project of Hubei Tobacco Company(027Y2020-013).
Poly-γ-glutamic acid(γ-PGA)is a natural polymer with various applications,and its high-viscosity hinders ox-ygen transmission and improvement of synthesis level.Vitreoscilla hemoglobin(VHB)has been introduced into v...
关键词：Vitreoscilla hemoglobin Expression element Twin-arginine translocation Poly-γ-glutamic acid Bacillus licheniformis 
Coarse-Grained Free-Energy Simulations of Conformational State Transitions in an Adenosine 5′-Triphosphate-binding Cassette Exporter被引量：1
《Chinese Journal of Chemical Physics》2020年第6期712-716,I0002,共6页Yun Huang Hao-chen Xu Jie-lou Liao 
supported by the National Natu-ral Science Foundation of China(No.21073170 and No.21273209).
ATP-binding cassette exporters transport many substrates out of cellular membranes via alternating between inward-facing and outward-facing conformations. Despite extensive research efforts over the past decades, unde...
关键词：ATP-binding cassette exporter Conformational state transition Coarse-grained molecular dynamics Potential of mean force 
CASSETTE TAPES Beijing label nugget records on DIYCassettes Made With Love
《城市漫步（上海版、英文）》2019年第9期34-34,共1页Bryan Grogan 
Weve made no secret of our love for physical releases;the combination of music and artwork in a package is one that is very close to our hearts.For underground and DIY bands,however,the idea of heavy runs of hundreds ...
关键词：BANDS VINYL release 
ATP-binding cassette transporters in progression and clinical outcome of pancreatic cancer: what is the way forward?被引量：7
《World Journal of Gastroenterology》2018年第29期3222-3238,共17页Aleksandra Adamska Marco Falasca 
Supported by Avner Pancreatic Cancer Foundation
Pancreatic ductal adenocarcinoma(PDAC) is one of the most aggressive diseases and is characterized by high chemoresistance, leading to the lack of effective therapeutic approaches and grim prognosis. Despite increasin...
关键词：PANCREATIC DUCTAL ADENOCARCINOMA MULTIDRUG resistance ATP-BINDING CASSETTE transporters Targeted therapies PANCREATIC DUCTAL ADENOCARCINOMA prognosis Predictive markers 
Olmutinib(HM61713) reversed multidrug resistance by inhibiting the activity of ATPbinding cassette subfamily G member 2 in vitro and in vivo被引量：9
《Acta Pharmaceutica Sinica B》2018年第4期563-574,共12页Zhiqiang Zhang Xiaoran Guo Kenneth K.W.To Zhen Chen Xiaona Fang Min Luo Chunling Ma Jianhua Xu Shirong Yan Liwu Fu 
supported by the National Natural Science Foundation of China (No. 81473233);Guangzhou Technology Program Foundation (No. 201604020079);The Science and Technology Project of Guangdong Province (No. 2016A030312014);The Scientific and Technological Leading Talent Project of Guangdong Province (2015)
Overexpressing of ATP-binding cassette(ABC) transporters is the essential cause of multidrug resistance(MDR), which is a significant hurdle to the success of chemotherapy in many cancers.Therefore, inhibiting the acti...
关键词：Olmutinib ABCG2 Multidrug resistance Tyrosine kinase inhibitor Chemotherapy ATPASE 
The classification of ATP-binding cassette subfamily A member 3 mutations using the cystic fibrosis transmembrane conductance regulator classification system被引量：1
《Pediatric Investigation》2018年第1期17-24,共8页Laura Denman Lael M. Yonker Thomas Bernard Kinane 
Importance: The ATP-binding cassette subfamily A member 3 (ABCA3) protein plays a vital role in surfactant homeostasis. Mutations in the ABCA3 gene lead to the development of interstitial lung disease. In the most sev...
关键词：ATP-BINDING CASSETTE transporter SUBFAMILY A CYSTIC fibrosis Genetics Interstitial lung diseases NEWBORN Respiratory DISTRESS syndrome 
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