云南高校图书馆联盟文献共享服务平台- ATP-BINDING

ATP-BINDING: 作品数：20被引量：104H指数：6; 导出分析报告; 相关作者：李欢李依民张娜刘亮亮彭亮更多>>; 相关机构：陕西中医药大学附属医院中国医学科学院北京协和医学院陕西中医药大学锦州医科大学更多>>; 相关期刊：《Acta Pharmacologica Sinica》《中国现代医学杂志》《World Journal of Gastroenterology》《Advances in Biological Chemistry》更多>>; 相关基金：国家自然科学基金国家重点基础研究发展计划陕西省自然科学基金云南省中青年学术和技术带头人后备人才项目更多>>

PD-L1 expression is regulated by ATP-binding of the ERBB3 pseudokinase domain: 《Genes & Diseases》2023年第4期1702-1713,共12页Yamu Li Zhonghua Liu Yiqing Zhao Jie Yang Tsan Sam Xiao Ronald A.Conlon Zhenghe Wang; supported by the National Institutes of Health(NIH)grants(No.R01CA256791,R01CA264320,P50CA150964,P30CA043703).; How PD-L1 expression is regulated in cancer is poorly understood.Here,we report that the ATP-binding activity of ERBB3 pseudokinase regulates PD-L1 gene expression in colorectal cancers(CRCs).ERBB3 is one of the four ...; 关键词：Colon cancer ERBB3 IMMUNOTHERAPY PD-L1 Pseudokinase

Identification of two ABCC transporters involved in malathion detoxification in the red flour beetle,Tribolium castaneum: 《Insect Science》2022年第4期1096-1104,共9页Janin Rösner Hans Merzendorfer; We are grateful to Johanne Tietmeyer for generating the used pGEM-T plasmids containing TcABC-cDNA inserts.This work was supported by a grant from the Deutsche Forschungsgemeinschaft(DFG Me2210/4-1).; ABC transporters have been suggested to be involved in insecticide detoxification in different insect species mainly based on the indirect observation of transcriptional upregulation of ABC gene expression in response...; 关键词：ATP-binding assette transporters(ABC transporter) B-cy fluthrin insecti-cide deoxification MALATHION TEBUFENOZIDE Tribolium castaneum

Efficacy of Shoushen granule on adenosine triphosphate binding cassette transporter A1, proprotein convertase subtilisin/kexin type 9 and toll-like receptor 4/nuclear factor kappa-B signaling pathway in ApoE-knockout mice被引量：5: 《Journal of Traditional Chinese Medicine》2019年第4期524-534,共11页Li Shanshan Cao Hui Shen Dingzhu Chen Chuan Xing Sanli Dou Fangfang Jia Qingling; Supported by the National Natural Science Foundation of China(The Role of TLR4/MyD88/NF-κB Signal Transduction Pathway and Expression of miRNA-146a in Atherosclerosis and the Intervention Mechanism of Shen Invigorating Compounds,No.81202731;Bushen Jiangzhi Recipe Protects Against Atherosclerosis via miR-27a-mediated PCSK9/ABCA1 Pathway,No.81873348);the Shanghai Natural Science Found(Inhibitory Mechanism of Chinese Herbal Compound,Shoushen Granule,for Invigorating Kidney in ApoE-/-Atherosclerosis Mouse Model by mir-19b Target Regulating ABCA1,No.16ZR1433900);the Shanghai Municipal Commission of Health and Family Planning Found(Effect of Kidney Invigoration and Lipid Intervention on the Atherosclerosis in ApoE-knockout Mice Based on mT OR signaling pathway of Autophagy System,No.201640217);Shanghai University of Traditional Chinese Medicine graduate"innovation ability training"special research projects(Mechanism of Bushen Jiangzhi Recipe Regulating TLR4/NF-κB Signaling Pathway Mediated by CD36 Through PCSK9 Targeted Regulation of apoE-/-mice Atherosclerosis,No.Y201858); OBJECTIVE: To evaluate the efficacy of Shoushen granule, prepared with four Chinese medicinals, on the targeted regulation of adenosine triphosphate binding cassette transporter A1(ABCA1) through proprotein convertase...; 关键词：Atherosclerosis ATP-BINDING cassette transporters PROPROTEIN convertases TOLL-LIKE receptor 4 NF-KAPPA B Shoushen GRANULE

ATP-binding cassette transporters in progression and clinical outcome of pancreatic cancer: what is the way forward?被引量：7: 《World Journal of Gastroenterology》2018年第29期3222-3238,共17页Aleksandra Adamska Marco Falasca; Supported by Avner Pancreatic Cancer Foundation; Pancreatic ductal adenocarcinoma(PDAC) is one of the most aggressive diseases and is characterized by high chemoresistance, leading to the lack of effective therapeutic approaches and grim prognosis. Despite increasin...; 关键词：PANCREATIC DUCTAL ADENOCARCINOMA MULTIDRUG resistance ATP-BINDING CASSETTE transporters Targeted therapies PANCREATIC DUCTAL ADENOCARCINOMA prognosis Predictive markers

The classification of ATP-binding cassette subfamily A member 3 mutations using the cystic fibrosis transmembrane conductance regulator classification system被引量：1: 《Pediatric Investigation》2018年第1期17-24,共8页Laura Denman Lael M. Yonker Thomas Bernard Kinane; Importance: The ATP-binding cassette subfamily A member 3 (ABCA3) protein plays a vital role in surfactant homeostasis. Mutations in the ABCA3 gene lead to the development of interstitial lung disease. In the most sev...; 关键词：ATP-BINDING CASSETTE transporter SUBFAMILY A CYSTIC fibrosis Genetics Interstitial lung diseases NEWBORN Respiratory DISTRESS syndrome

铁皮石斛2个F家族ABC转运蛋白基因的克隆和表达研究被引量：10: 《中草药》2017年第15期3153-3159,共7页李依民雷根平颜永刚彭亮张娜刘亮亮黑小斌李欢张岗郭顺星; 国家自然科学基金项目(31101608);陕西省自然科学基金项目(2017JM8030);陕西省青年科技新星项目(2012KJXX-44); 目的克隆铁皮石斛Dendrobium officinale ABC(ATP-binding cassette)转运蛋白F家族基因并进行生物信息学分析。方法利用RACE从铁皮石斛叶片cDNA中分离ABC基因,并进行编码蛋白相对分子质量、等电点、结构域、信号肽、跨膜域及亚细胞定位...; 关键词：铁皮石斛 ATP-BINDING CASSETTE 转运蛋白克隆表达模式

小鼠CD45^-/CD31^+肺侧群细胞诱导分化的研究: 《中国现代医学杂志》2017年第6期17-22,共6页张明杰李宗泽徐杨梁迅; 国家自然科学基金(No:81370619); 目的探讨在体外诱导分化肺侧群细胞(SP)的特性。方法取小鼠肺组织,流式细胞术分选小鼠白细胞分化抗原(CD)45^-/CD31^+肺SP;免疫荧光检测分选肺SP三磷酸腺苷结合转运蛋白G超家族成员2(ABCG2)的表达;逆转录聚合酶链反应(RT-PCR)检测肺SP中...; 关键词：侧群细胞血管内皮细胞三磷酸腺苷结合转运蛋白G超家族成员2 ATP-BINDING CASSETTE sub-family G member 2

Regulation of Intestinal Cholesterol Absorption: A Disease Perspective: 《Advances in Biological Chemistry》2017年第1期60-75,共16页Jahangir Iqbal Ali Al Qarni Abbas Hawwari; Hypercholesterolemia promotes atherosclerosis and precise regulation of cholesterol homeostasis is essential. Besides risk factor for cardiovascular disease, abnormalities in cholesterol metabolism have been associate...; 关键词：CHOLESTEROL Absorption ATHEROSCLEROSIS METABOLIC DISEASE NPC1L1 ATP-BINDING CASSETTE Transporters

Mechanisms of drug resistance in colon cancer and its therapeutic strategies被引量：34: 《World Journal of Gastroenterology》2016年第30期6876-6889,共14页Tao Hu Zhen Li Chun-Ying Gao Chi Hin Cho; Drug resistance develops in nearly all patients with colon cancer, leading to a decrease in the therapeutic efficacies of anticancer agents. This review provides an up-to-date summary on over-expression of ATPbinding ...; 关键词：COLON cancer Drug resistance ATP-BINDING CASSETTE transporters EVASION of apoptosis Autophagy

Sensitivity of KATp channels to cellular metabolic disorders and the underlying structural basis被引量：2: 《Acta Pharmacologica Sinica》2016年第1期134-142,共9页Chun-gang LI Wen-yu CUI Hai WANG; Aim： ATP-sensitive potassium （KATP） channels formed by a combination of SUR/Kir6.x subunits play a crucial role in protection against hypoxic or ischemic injuries resulting from cell metabolic disorders. In this st...; 关键词：KATP SUR/Kir6.x cell metabolic disorders Na-azide ATP-BINDING pH-sensing nucleotide-binding domains

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