CCAAT

作品数:50被引量:118H指数:5
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相关领域:医药卫生生物学更多>>
相关作者:黄光存张锦生谢渭芬陈苗赵旭赟更多>>
相关机构:南京医科大学西北农林科技大学复旦大学上海医学院江苏省人民医院更多>>
相关期刊:《Chinese Medical Journal》《中国实验血液学杂志》《农业生物技术学报》《现代妇产科进展》更多>>
相关基金:国家自然科学基金浙江省中医药重点研究计划浙江省中医药科技计划项目浙江省公益性技术应用研究计划项目更多>>
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Magnolol inhibits appetite and causes visceral fat loss through Growth/differentiation factor-15(GDF-15)by activating transcription factor 4-CCAAT enhancer binding proteinγ-mediated endoplasmic reticulum stress responses
《Chinese Journal of Natural Medicines》2025年第3期334-345,共12页Keru Cheng Yanyun Zhou Yilong Hao Shengyun Wu Nanping Wang Peng Zhang Yinfang Wang 
supported by the National Natural Science Foundation of China(Nos.82171552 and 82170479);the Natural Science Foundation of Shanghai Ctiy(No.21ZR1457500);the Science and Technology Bureau of Shanghai Putuo District(No.ptkwws202102).
Magnolol,a compound extracted from Magnolia officinalis,demonstrates potential efficacy in addressing metabolic dysfunction and cardiovascular diseases.Its biological activities encompass anti-inflammatory,antioxidant...
关键词:MAGNOLOL Growth/differentiation factor-15 Activating transcription factor 4 CCAAT enhancer binding proteinγ ENHANCER Metabolic disorder 
基于PEPK/CHOP途径探讨补中益气汤联合针刺夹脊穴治疗脊髓损伤尿潴留的分子机制
《中国老年学杂志》2024年第12期3005-3009,共5页李正飞 张任 赵国瑞 
天津市教委科研计划项目(2018KJ028)
目的基于蛋白激酶样内质网激酶(PERK)/CCAAT-增强子同源性蛋白(CHOP)通路探究补中益气汤联合针刺夹脊穴治疗脊髓损伤性尿潴留(UR)的分子机制。方法建立脊髓损伤性UR大鼠模型,并随机分为模型组、补中益气汤组、针刺夹脊穴组、针药联合组...
关键词:补中益气汤 针刺夹脊穴 尿潴留 内质网应激 逼尿肌细胞凋亡 蛋白激酶样内质网激酶 CCAAT-增强子同源性蛋白 
发育性内皮基因座-1在人冠状动脉粥样硬化斑块中的表达及其与冠心病的关系
《贵州医科大学学报》2024年第1期34-40,共7页路艳林 周明 李曼 彭进 戴佳琳 丁九阳 万昌武 汪家文 王杰 夏冰 
国家自然科学基金(82060340);贵州省科技计划项目(黔科合基础-ZK[2021]一般487);贵州医科大学国家自然科学基金培育项目(20NSP083)。
目的 检测发育性内皮基因座-1(DEL-1)在人冠状动脉粥样硬化斑块中的表达,探讨其参与冠心病(CHD)发生发展的相关机制。方法 将58例人冠状动脉标本分为CHD组(25例)和对照组(CON组,33例),以左前降支作为研究对象;通过HE染色检测冠状动脉内...
关键词:发育性内皮基因座-1 冠心病猝死 白细胞介素-17 糖原合成酶激酶-3β/CCAAT增强结合蛋白β通路 炎症反应 动脉粥样硬化 
茯苓酸对人骨肉瘤细胞系MG-63的增殖凋亡、迁移侵袭影响及PERK/CCAAT信号通路调控作用
《山东医药》2023年第30期1-5,共5页施擎宇 黄帆 王冬明 
目的观察茯苓酸(PA)对人骨肉瘤细胞系MG-63增殖、迁移、凋亡和侵袭的影响,并探讨PA对蛋白激酶R样内质网激酶(PERK)/CCAAT增强子结合蛋白同源蛋白(CHOP)信号通路的调控作用。方法体外培养MG-63细胞,分为对照组、低浓度PA组(PA-L组)、中浓...
关键词:茯苓酸 骨肉瘤 细胞增殖 细胞凋亡 细胞侵袭 蛋白激酶R样内质网激酶 CCAAT增强子结合蛋白同源蛋白 
The CCAAT/Enhancer Binding Protein Beta(cebpb)is essential for the development of enveloping layer(EVL)in zebrafish
《Aquaculture and Fisheries》2023年第3期252-260,共9页Xin Zhang Zhichao Wu Mengdi Bu Ruiqin Hu Xiaowen Zhang Wenhao Li Liangbiao Chen 
supported by National Key Research and Development Program of China[2018YFD0900601];L.Chen,the open project fund from Laboratory for Marine Biology and Biotechnology,Qingdao National Laboratory for Marine Science(OF2019NO01);Doctor Fund of Shanghai Ocean University(A2-2006-21-200304);Science and Technology Development Fund of Shanghai Ocean University(A2-2006-20-200201)to W.Li.
Epiboly,the coordinated spreading of the enveloping layer(EVL),the yolk syncytial layer(YSL)and the deep cells(DCs)toward the vegetal pole,is required for gastrulation.Interference with the EVL leads to early developm...
关键词:Cebpb Single-cell RNA sequencing ZEBRAFISH Enveloping layer(EVL) 
CCAAT/Enhancer-Binding Proteins in Fibrosis:Complex Roles Beyond Conventional Understanding
《Research》2023年第1期231-272,共42页Lexun Wang Jiaojiao Feng Yanyue Deng Qianqian Yang Quxing Wei Dewei Ye Xianglu Rong Jiao Guo 
supported by the Major basic and applied basic research projects of Guangdong Province of China(2019B030302005);the Natural Science Foundation of China(81830113);the National Key Research and Development Program of China(2018YFC1704200);the Basic and applied basic research project of Guangdong Province of China(2020A1515010155);the“Innovation and Strengthening University Project”Subsidized Project of Guangdong Pharmaceutical University(2018KTSCX112).
CCAAT/enhancer-binding proteins(C/EBPs)are a family of at least six identified transcription factors that contain a highly conserved basic leucine zipper domain and interact selectively with duplex DNA to regulate tar...
关键词:ORGANS expression COMPLEX 
Tetratricopeptide repeat domain 36 deficiency mitigates renal tubular injury by inhibiting TGF-β1-induced epithelialemesenchymal transition in a mouse model of chronic kidney disease
《Genes & Diseases》2022年第6期1716-1726,共11页Xin Yan Rui Peng Yilu Ni Lei Chen Qingling He Qianyin Li Qin Zhou 
This work was supported by the National Natural Science Foundation of China(No.81873932,81802549);the Scientific and Technological Research Program of Chongqing Municipal Education Commission(No.KJQN202000438);Chongqing Science and Technology Commission(No.cstc2019jscx-dxwtBX0032).
The damage of proximal tubular epithelial cells(PTECs)is considered a central event in the pathogenesis of chronic kidney disease(CKD)and deregulated repair processes of PTECs result in epithelialemesenchymal transiti...
关键词:CCAAT enhancer binding protein beta Chronic kidney disease Epithelialmesenchymal transition Renal fibrosis SMADfamilybember 3 Tetratricopeptide repeat domain 36 
Expression of COX-2 and transcription factor CCAAT enhancer binding proteinβin refractory sinusitis with nasal polyps and its significance
《中国医学文摘(耳鼻咽喉科学)》2021年第2期11-17,共7页Jingyu Gao Fanxing Meng Chaowu Jiang Yongmei Yu Ruan Biao 
Health Science and Technology Program of Yunnan Province(No.2010NS034);Joint Special Project of Yunnan Provincial Science and Technology Department/Kunming Medical University Applied Basic Research(No.201901C07041)。
Objective To study the expression and significance of COX-2 and C/EBP-βin refractory sinusitis with nasal polyps,and to explore the relationship between them and the recurrence of sinusitis with nasal polyps.Methods ...
关键词:Cyclooxygenase-2 Transcription factor CCAAT enhancer binding proteinβ Refractory sinusitis with nasal polyps IMMUNOBLOT 
Oleic acid Stimulates the Formation of Adipocyte-Like Cells from Bovine Satellite Cells via <i>G-Protein Coupled Receptor 43</i>and <i>CCAAT/Enhancer-Binding Protein Beta</i>被引量:2
《Open Journal of Animal Sciences》2020年第4期649-664,共16页J. Kim K. Chung L. K. Fuerniss B. J. Johnson 
Numerous physiological and pathological processes are controlled by free fatty acids, which act as signaling molecules in mammals. We hypothesized that oleic acid (Ole) might stimulate the formation of satellite-cell-...
关键词:Bovine Satellite Cells GPR43 Intramuscular Adipose Tissue Oleic Acid 
Celecoxib attenuates hepatocyte apoptosis by inhibiting endoplasmic reticulum stress in thioacetamide-induced cirrhotic rats被引量:5
《World Journal of Gastroenterology》2020年第28期4094-4107,共14页Wei Su Yang Tai Shi-Hang Tang Yan-Ting Ye Chong Zhao Jin-Hang Gao Bi-Guang Tuo Cheng-Wei Tang 
the National Natural Science Fund of China,No.U1702281,No.81670551,and No.81873584.
BACKGROUND Endoplasmic reticulum(ER)stress is an important mechanism in the progression of chronic and acute liver diseases,especially in the progression and recovery of liver fibrosis.Excessive and long-term ER stres...
关键词:Liver fibrosis Endoplasmic reticulum stress CELECOXIB CYCLOOXYGENASE-2 CCAAT/enhancer binding protein homologous protein Apoptosis 
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