the National Natural Science Foundation of China(32141002,81991535 and 32202863);China Postdoctoral Science Foundation(2021 M703528).
Ceftazidime-avibactam (CZA) is a recently approved combination synthetic β-lactamase inhibitor used in human clinical medicine. Cases of CZA resistance in humans have already been reported, but limited research has i...
supported by grants from National Key Research and Development Program of China (2020YFA0509000);National Natural Science Foundation of China (31830112,32030024,31525016 to JFC,32170769,31970702 to CDL);Shanghai Rising-Star Program (21QA1409700);Program of Shanghai Academic Research Leader (19XD1404200);Personalized Medicines-Molecular Signature-based Drug Discovery and Development,the Strategic Priority Research Program of the Chinese Academy of Sciences (XDA12010101);the Youth Innovation Promotion Association of the Chinese Academy of Sciences (2020266);the Young Elite Scientist Sponsorship Program by CAST (2019QNRC001);National Ten Thousand Talents Program,and the Fundamental Research Funds for the Central Universities (22120220378,22120220499).
Dear Editor,Severe acute respiratory syndrome coronavirus 2(SARS-CoV-2)has coexisted with human beings over 3 years.It has undergone considerable evolution and several variants of concern(VOCs),including Alpha,Beta,Ga...
Objective: to compare and analyze the clinical efficacy of cefoperazone sulbactam and ceftazidime in the treatment of complicated urinary tract infections and to provide a theoretical basis for the clinical drug treat...
supported by the National Key Research and Development Program of China (2017YFC1200200);Major Infectious Diseases such as AIDS and Viral Hepatitis Prevention and Control Technology Major Projects (2018ZX10712-001);National Natural Science Foundation of China (81702045 and 81902030);Shenzhen Basic Research projects (JCYJ20190807144409307)
Carbapenem resistance presents a major challenge for the global public health network, as clinical infections caused by carbapenem-resistant organisms(CRO) are frequently associated with significant morbidity and mort...
Objective: to analyze the clinical effect of the injection combined with ceftazidime in the treatment of children with bronchial pneumonia. Methods: a total of 60 patients diagnosed with bronchial pneumonia in our hos...
After online publication of the article1 we noticed an error in citations for affiliation in the supplementary materials published in this article.The citations for affiliation in the article were reordered during the...
grants from National Key Research and Development Program of China(2020YFA0509102);National Natural Science Foundation of China(32030024,31830112,31525016 to J.F.C.,31970702,31701219 to C.D.L.);Program of Shanghai Academic Research Leader(19XD1404200);Personalized Medicines-Molecular Signature-based Drug Discovery and Development,the Strategic Priority Research Program of the Chinese Academy of Sciences(XDA12010101);the Youth Innovation Promotion Association of the Chinese Academy of Sciences(2020266);the Young Elite Scientist Sponsorship Program by CAST(2019QNRC001);National Ten Thousand Talents Program.
Dear Editor,Coronavirus disease 2019(COVID-19)has spread globally as a severe pandemic,which is caused by a novel coronavirus named Severe Acute Respiratory Syndrome coronavirus 2(SARS-CoV-2).1 COVID-19 is a serious t...
A surveillance study was undertaken to identify prominent β-lactamase encoding genes in 131 carbapenem non-susceptible gram-negative clinical isolates at a New York City community hospital. KPC carbapenemases were de...
We present a case of keratitis caused by Stenotrophomonas maltophilia in a therapeutic contact lens user with trichiasis and symblepharon. This keratitis was initially diagnosed as caused by Achromobacter xylosoxidans...
Supported by a Sub-project of National Basic Research Program of China(No.2006CB504401);the National Natural Science Foundation of China(No.31060348,No.30860207);Grants of Science and Technology Program of Ningxia to Yujiong Wang(No.Z2006-1-75001,KGZ-12-10-02)
Objective: To evaluate the antimicrobial activity of total alkaloids extracted from Sophorea alopecuroides L. (TASA) against clinical isolated extended-spectrum beta-lactamases (ESBLs) producing Escherichia coil ...