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CELL_LINE: 作品数：757被引量：2403H指数：20; 导出分析报告; 相关作者：赵艳玲袁海龙陈蔚文葛文赵群更多>>; 相关机构：中国医学科学院北京协和医学院第二军医大学华中科技大学复旦大学更多>>; 相关期刊：更多>>; 相关基金：国家自然科学基金国家重点基础研究发展计划国家高技术研究发展计划广东省自然科学基金更多>>

IFNα2b/5-FU inhibits proliferation and cell cycle of squamous carcinoma cell line Cal27: 《International Journal of Ophthalmology(English edition)》2025年第4期565-574,共10页Zong-Bo Wu Gong-Yue Wang Bei Wang Xi Peng Jia-Song Wang Ming-Chang Zhang Wen Geng Hua-Tao Xie; All data and materials are available in the article upon reasonable request to the corresponding author.Foundations:Supported by the National Natural Science Foundation of China(No.82070934;No.82171025).; AIM:To investigate the pathological features of ocular surface squamous neoplasia(OSSN)and evaluate the synergistic therapeutic effects of interferon-α2b(IFNα2b)and 5-fluorouracil(5-FU)on cellular proliferation,migr...; 关键词：ocular surface squamous neoplasia squamous carcinoma cells interferon-α2b 5-FLUOROURACIL combination index

GAPDH suppresses adenovirus-induced oxidative stress and enables a superfast production of recombinant adenovirus: 《Genes & Diseases》2024年第6期367-380,共14页Guozhi Zhao Piao Zhao Yonghui Wang Hui Zhang Yi Zhu Jiamin Zhong Wulin You Guowei Shen Changi Luo Ou Mei Xingye Wu Jingjing Li Yi Shu Hongwei Wang Wiliam Wagstaff Hue HLuu Yang Bi Lewis LShi Russell RReid Tong-Chuan He Li Jiang Wei Tang Jiaming Fan Ziwei Tang; supported in part by research grants from the Natural Science Foundation of China (No.82000744 to ZT,and 82102696 to J.F.);the Chongqing Bayu Young Scholar Award (China) (to J.F.);the 2019 Funding for Postdoctoral Research (Chongqing Human Resources and Social Security Bureau of China) (No.298 to J.F.);the National Institutes of Health (No.CA226303 to T.C.H.,DE030480 to R.R.R.);supported by the Medical Scientist Training Program of the National Institutes of Health (USA) (No.T32 GM007281);supported in part by The University of Chicago Cancer Center Support Grant (No.P30CA014599);the National Center for Advancing Translational Sciences of the National Institutes of Health through grant number 2UL1TR002389-06 that funds the Institute for Translational Medicine (ITM);supported by the Mabel Green Myers Research Endowment Fund and The University of Chicago Orthopaedics Alumni Fund.; Recombinant adenovirus(rAdV)is a commonly used vector system for gene transfer.Efficient initial packaging and subsequent production of rAdV remains time-consuming and labor-intensive,possibly attributable to rAdv inf...; 关键词：GAPDH GENETHERAPY Oxidative stress Packaging cell line Reactive oxygen species Recombinant adenovirus

Generation and characterization of a novel ovariole cell line derived from Spodoptera frugiperda in China with sensitivity to both SfMNPV and AcMNPV: 《Virologica Sinica》2024年第6期929-937,共9页Yan Tong Wenyi Jin Xuan Li Lin Guo Gang Luo Qian Meng Jihong Zhang Qilian Qin Huan Zhang; funded by the National Key Research and Development Program of China(Grant number 2022YFD1400700);Initiative Scientific Research Program,Institute of Zoology,Chinese Academy of Sciences(Grant number 2023IOZ010).; Spodoptera frugiperda multiple nucleopolyhedrovirus(SfMNPV),belonging to the species Alphabaculovirus spofrugiperdae,has been recently registered as an insecticide in China.This virus has a specific effect on the glob...; 关键词：Spodoptera frugiperda multiple nucleopolyhedrovirus(SfMNPV) Autographa californica multiple nucleopolyhedrovirus(AcMNPV) Spodoptera frugiperda Mitochondrial COX1 Insect ovarian cell line

MHCLSyn:Multi-View Hypergraph Contrastive Learning for Synergistic Drug Combination Prediction: 《Big Data Mining and Analytics》2024年第4期1273-1286,共14页Lei Li Guodong Lü Chunhou Zheng Renyong Lin Yansen Su; supported by the National Key Research and Development Program of China(No.2021YFE0102100);the National Natural Science Foundation of China(Nos.62322301,62172002,and 82060373);the Outstanding Youth Research Project of Universities in Anhui Province(No.2022AH020010);the University Synergy Innovation Program of Anhui Province(Nos.GXXT-2022-035 and GXXT-2021-039);the Xinjiang Tianshan Project(No.2022TSYCLJ0032).; In the field of cancer treatment,drug combination therapy appears to be a promising treatment strategy compared to monotherapy.Recently,plenty of computational models are gradually applied to prioritize synergistic dr...; 关键词：synergistic drug combinations cell lines multi-way relations multi-view hypergraph contrastive learning

Retraction:miR-183 modulates cell apoptosis and proliferation in tongue squamous cell carcinoma SCC25 cell line: 《Oncology Research》2024年第10期1691-1691,共1页Oncology Research Editorial Office; Following the publication,concerns have been raised about a number of figures in this article.An unexpected area of similarity was identified in terms of the cellular data,where the results from differently performed ...; 关键词：SHAPED SIMILARITY raised

Retraction:MicroRNA-21 Inhibits the Apoptosis of Osteosarcoma Cell Line SAOS-2 via Targeting Caspase 8: 《Oncology Research》2024年第9期1531-1531,共1页Oncology Research Editorial Office; Following the publication,concerns have been raised about a number of figures in this article.An unexpected area of similarity was identified in terms of the cellular data,where the results from differently performed ...; 关键词：APOPTOSIS shaped similarity

New 4-imino-4H-Chromeno[2,3-d]Pyrimidin-3(5H)-Amine: Synthesis, Cytotoxic Effects on Tumoral Cell Lines and in Silico ADMET Properties: 《International Journal of Organic Chemistry》2024年第3期107-122,共16页Marwa Dhiabi Sirine Karoui Mehdi Fakhfakh Souhir Abid Emmanuelle Limanton Rémy Le Guével Thierry Charlier Ludovic Paquin Jean-Pierre Bazureau Houcine Ammar; The synthesis of new 4-imino-4H-chromeno[2,3-d]pyrimidin-3(5H)-amine in four steps including one step under microwave dielectric heating is reported. The structural identity of the synthesized compounds was establishe...; 关键词：2-Amino-4H-Chromene 4H-Chromeno[2 3-d]Pyrimidin-3(5H)-Amine Microwave Irradiation Tumoral Cell Line in Silico ADMET

Hypoxia activates the hypoxia-inducible factor-1α/vascular endothelial growth factor pathway in a prostatic stromal cell line:A mechanism for the pathogenesis of benign prostatic hyperplasia: 《Current Urology》2024年第3期185-193,共9页Tao Zhang Changlin Mao Yao Chang Jiaju Lyu Delong Zhao Sentai Ding; the financial support granted from the Shandong Province Key Research and Development Projects(no.2016GSF201147);the Science and Technology Development Program of Jinan(no.201704127).; Background The development of benign prostatic hyperplasia(BPH)is closely related to hypoxia in the prostatic stroma,and the hypoxia-inducible factor-1α/vascular endothelial growth factor(HIF-1α/VEGF)pathway has bee...; 关键词：Benign prostatic hyperplasia Hypoxia-inducible factor-1α Vascular endothelial growth factor PATHOGENESIS miR-17-5p

Establishment and transcriptome analysis of single blastomerederived cell lines from zebrafish: 《Journal of Genetics and Genomics》2024年第9期957-969,共13页Jia Xu Siqi Liu Yirui Ai Yunbin Zhang Shifeng Li Yiping Li; supported by the National Key Research and Development Program of China(2018YFA0801003 and 2019YFA0109900);the Center for Excellence in Molecular Cell Science(2021DF06);supported by the Shanghai Municipal Science and Technology Major Project.; Maintaining chromosome euploidy in zebrafish embryonic cells is challenging because of the degradation of genomic integrity during cell passaging.In this study,we report the derivation of zebrafish cell lines from sin...; 关键词：ZEBRAFISH Single embryo Cell lines Sngle-cell RNA sequencing(scRNA-Seq) Embryonic epidermis EPITHELIUM

Establishment and characterization of a canine chondrosarcoma cell line:Mango: 《Animal Diseases》2024年第3期186-197,共12页Meilin Wang Xiao Wang Lixin He Hongbo Gao Wenxuan Li Huili Feng Qingyuan Zhao Wenwen Zhang Chengzong Li Bohan Zhang Changwei Qiu; the National Natural Science Foundation of China(Grant Number:32172925).; In the global progress of bone tumor research,established stable and long-lasting transgenic chondrosarcoma(CSA)cell lines are rare,mainly of murine and human origin,while the establishment of canine CSA cell lines ha...; 关键词：Canine chondrosarcoma Cell line ESTABLISHMENT CHARACTERIZATION Tumorigenicity

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