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CELL_LINE: 作品数：762被引量：2406H指数：20; 导出分析报告; 相关作者：赵艳玲袁海龙陈蔚文葛文赵群更多>>; 相关机构：中国医学科学院北京协和医学院第二军医大学华中科技大学复旦大学更多>>; 相关期刊：更多>>; 相关基金：国家自然科学基金国家重点基础研究发展计划国家高技术研究发展计划广东省自然科学基金更多>>

Empowering the NSC-34 cell line as a motor neuron model: Cytosine arabinoside's action: 《Neural Regeneration Research》2026年第1期357-364,共8页Giuseppe Vitale Susanna Amadio Francesco Liguori Cinzia Volonté; supported by FATALSDrug Project [Progetti di Ricerca@CNR SAC.AD002.173.058] from National Research Council,Italy (to CV)。; The NSC-34 cell line is a widely recognized motor neuron model and various neuronal differentiation protocols have been exploited. Under previously reported experimental conditions, only part of the cells resemble dif...; 关键词：cytosine arabinoside Islet2 Hb9 Ki67 mitosis inhibition neurite initiation neurite regeneration neuronal differentiation protocol NSC-34 P75

Establishment and characterization of a new human gallbladder cancer cell line,OCUG-2: 《World Journal of Experimental Medicine》2025年第2期130-141,共12页Qiang Wang Canfeng Fan Gen Tsujio Takashi Sakuma Koji Maruo Yurie Yamamoto Daiki Imanishi Kyoka Kawabata Hinano Nishikubo Saki Kanei Rika Aoyama Syuhei Kushiyama Masaichi Ohira Masakazu Yashiro; BACKGROUND Gallbladder cancer(GBC)is a highly aggressive malignant tumor originating from the biliary tract.As one of the most common malignancies in the biliary system,GBC is particularly challenging due to its tende...; 关键词：Gallbladder cancer Cell line Insulin-like growth factor 1 receptor Molecular target Mouse model

IFNα2b/5-FU inhibits proliferation and cell cycle of squamous carcinoma cell line Cal27: 《International Journal of Ophthalmology(English edition)》2025年第4期565-574,共10页Zong-Bo Wu Gong-Yue Wang Bei Wang Xi Peng Jia-Song Wang Ming-Chang Zhang Wen Geng Hua-Tao Xie; All data and materials are available in the article upon reasonable request to the corresponding author.Foundations:Supported by the National Natural Science Foundation of China(No.82070934;No.82171025).; AIM:To investigate the pathological features of ocular surface squamous neoplasia(OSSN)and evaluate the synergistic therapeutic effects of interferon-α2b(IFNα2b)and 5-fluorouracil(5-FU)on cellular proliferation,migr...; 关键词：ocular surface squamous neoplasia squamous carcinoma cells interferon-α2b 5-FLUOROURACIL combination index

RNA-seq analysis of mitochondria-related genes regulated by AMPK in the human trophoblast cell line BeWo: 《Animal Models and Experimental Medicine》2025年第4期649-661,共13页Bin Wu Albert Gao Bin He Yun Chen Xiangfeng Kong Fayuan Wen Haijun Gao; Dean's Office Howard University College of Medicine,Grant/Award Number:Bridge Fund/Pilot Study Award;National Center on Minority Health and Health Disparities,Grant/Award Number:RCMI/IDC Award U54MD007597;National Institute of Child Health and Human Development,Grant/Award Number:R03HD095417 and R16HD116702。; Background:How AMP activated protein kinase(AMPK)signaling regulates mito-chondrial functions and mitophagy in human trophoblast cells remains unclear.This study was designed to investigate potential players mediating...; 关键词：AMPK ATP production gene expression MITOCHONDRIA RNA-SEQ TROPHOBLAST

Melanoma cell line-derived exosomal miR-424-5p:a key promoter of angiogenesis through LATS2 interaction: 《Oncology Research》2025年第2期357-367,共11页JUNWEI DU QIANG ZHANG JING ZHANG MAIERDANJIANG MAIHEMUTI HAIYANG HE RENBING JIANG; Natural Science Foundation of Xinjiang Uygur Autonomous Region(2022D01C803).; Objectives:Melanoma is a highly aggressive and metastatic form of cancer,and the role of exosomal microRNAs(miRNAs)in its progression remains largely unexplored.This study aimed to investigate the effects of melanoma ...; 关键词：Exosomal miR-424-5p Large tumor suppressor kinase 2(LATS2) Cell proliferation Cancer progression Therapeutic targets

GAPDH suppresses adenovirus-induced oxidative stress and enables a superfast production of recombinant adenovirus: 《Genes & Diseases》2024年第6期367-380,共14页Guozhi Zhao Piao Zhao Yonghui Wang Hui Zhang Yi Zhu Jiamin Zhong Wulin You Guowei Shen Changi Luo Ou Mei Xingye Wu Jingjing Li Yi Shu Hongwei Wang Wiliam Wagstaff Hue HLuu Yang Bi Lewis LShi Russell RReid Tong-Chuan He Li Jiang Wei Tang Jiaming Fan Ziwei Tang; supported in part by research grants from the Natural Science Foundation of China (No.82000744 to ZT,and 82102696 to J.F.);the Chongqing Bayu Young Scholar Award (China) (to J.F.);the 2019 Funding for Postdoctoral Research (Chongqing Human Resources and Social Security Bureau of China) (No.298 to J.F.);the National Institutes of Health (No.CA226303 to T.C.H.,DE030480 to R.R.R.);supported by the Medical Scientist Training Program of the National Institutes of Health (USA) (No.T32 GM007281);supported in part by The University of Chicago Cancer Center Support Grant (No.P30CA014599);the National Center for Advancing Translational Sciences of the National Institutes of Health through grant number 2UL1TR002389-06 that funds the Institute for Translational Medicine (ITM);supported by the Mabel Green Myers Research Endowment Fund and The University of Chicago Orthopaedics Alumni Fund.; Recombinant adenovirus(rAdV)is a commonly used vector system for gene transfer.Efficient initial packaging and subsequent production of rAdV remains time-consuming and labor-intensive,possibly attributable to rAdv inf...; 关键词：GAPDH GENETHERAPY Oxidative stress Packaging cell line Reactive oxygen species Recombinant adenovirus

Generation and characterization of a novel ovariole cell line derived from Spodoptera frugiperda in China with sensitivity to both SfMNPV and AcMNPV: 《Virologica Sinica》2024年第6期929-937,共9页Yan Tong Wenyi Jin Xuan Li Lin Guo Gang Luo Qian Meng Jihong Zhang Qilian Qin Huan Zhang; funded by the National Key Research and Development Program of China(Grant number 2022YFD1400700);Initiative Scientific Research Program,Institute of Zoology,Chinese Academy of Sciences(Grant number 2023IOZ010).; Spodoptera frugiperda multiple nucleopolyhedrovirus(SfMNPV),belonging to the species Alphabaculovirus spofrugiperdae,has been recently registered as an insecticide in China.This virus has a specific effect on the glob...; 关键词：Spodoptera frugiperda multiple nucleopolyhedrovirus(SfMNPV) Autographa californica multiple nucleopolyhedrovirus(AcMNPV) Spodoptera frugiperda Mitochondrial COX1 Insect ovarian cell line

MHCLSyn:Multi-View Hypergraph Contrastive Learning for Synergistic Drug Combination Prediction: 《Big Data Mining and Analytics》2024年第4期1273-1286,共14页Lei Li Guodong Lü Chunhou Zheng Renyong Lin Yansen Su; supported by the National Key Research and Development Program of China(No.2021YFE0102100);the National Natural Science Foundation of China(Nos.62322301,62172002,and 82060373);the Outstanding Youth Research Project of Universities in Anhui Province(No.2022AH020010);the University Synergy Innovation Program of Anhui Province(Nos.GXXT-2022-035 and GXXT-2021-039);the Xinjiang Tianshan Project(No.2022TSYCLJ0032).; In the field of cancer treatment,drug combination therapy appears to be a promising treatment strategy compared to monotherapy.Recently,plenty of computational models are gradually applied to prioritize synergistic dr...; 关键词：synergistic drug combinations cell lines multi-way relations multi-view hypergraph contrastive learning

Retraction:miR-183 modulates cell apoptosis and proliferation in tongue squamous cell carcinoma SCC25 cell line: 《Oncology Research》2024年第10期1691-1691,共1页Oncology Research Editorial Office; Following the publication,concerns have been raised about a number of figures in this article.An unexpected area of similarity was identified in terms of the cellular data,where the results from differently performed ...; 关键词：SHAPED SIMILARITY raised

Retraction:MicroRNA-21 Inhibits the Apoptosis of Osteosarcoma Cell Line SAOS-2 via Targeting Caspase 8: 《Oncology Research》2024年第9期1531-1531,共1页Oncology Research Editorial Office; Following the publication,concerns have been raised about a number of figures in this article.An unexpected area of similarity was identified in terms of the cellular data,where the results from differently performed ...; 关键词：APOPTOSIS shaped similarity

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