TROPHOBLAST

作品数：69被引量：142H指数：7
导出分析报告
相关领域：医药卫生更多>>
相关作者：王晗知袁烁刘凤娟何国琳邓高丕更多>>
相关机构：第二军医大学广州中医药大学第一附属医院重庆医科大学浙江大学医学院附属妇产科医院更多>>
相关期刊：更多>>
相关基金：国家自然科学基金国家重点基础研究发展计划中国博士后科学基金上海市青年科技启明星计划更多>>
-
在结果中检索

检索结果分析

结果分析中...
共 条 记 录，以下是1-10
全选清除导出
参考文献引证文献引用追踪
视图：
排序：
RNA-seq analysis of mitochondria-related genes regulated by AMPK in the human trophoblast cell line BeWo
《Animal Models and Experimental Medicine》2025年第4期649-661,共13页Bin Wu Albert Gao Bin He Yun Chen Xiangfeng Kong Fayuan Wen Haijun Gao 
Dean's Office Howard University College of Medicine,Grant/Award Number:Bridge Fund/Pilot Study Award;National Center on Minority Health and Health Disparities,Grant/Award Number:RCMI/IDC Award U54MD007597;National Institute of Child Health and Human Development,Grant/Award Number:R03HD095417 and R16HD116702。
Background:How AMP activated protein kinase(AMPK)signaling regulates mito-chondrial functions and mitophagy in human trophoblast cells remains unclear.This study was designed to investigate potential players mediating...
关键词：AMPK ATP production gene expression MITOCHONDRIA RNA-SEQ TROPHOBLAST 
Elevated levels of KLF12 impair trophoblast syncytialization via GCM1 downregulation
《Reproductive and Developmental Medicine》2024年第3期131-137,共7页Qing-Qing Shi Xing Wu Nan-Nan Kang Ji-Dong Zhou Xin Zhen Ze-Wu Li Gui-Jun Yan Hai-Xiang Sun Jing-Yu Liu Yang Liu 
supported by the National Natural Science Foundation of China(82030040,82301897,and 82171653);the Natural Science Foundation of Nanjing Drum Tower Hospital,Nanjing University Medical School(2022-JCYJ-QP-54);the Natural Science Foundation of Shandong(ZR202111300553 and ZR2022MH094).
Objective:Placental dysfunction is a major contributor to miscarriages in humans.We observed elevated expression of Kruppel-like factor 12(KLF12)in placental villi of women who experienced miscarriage compared to that...
关键词：KLF12 GCM1 Syncytialization MISCARRIAGE 
Dynamic intrauterine crosstalk promotes porcine embryo implantation during early pregnancy
《Science China(Life Sciences)》2024年第8期1676-1696,共21页Xupeng Zang Shengchen Gu Wenjing Wang Junsong Shi Jianyu Gan Qun Hu Chen Zhou Yue Ding Yanjuan He Lei Jiang Ting Gu Zheng Xu Sixiu Huang Huaqiang Yang Fanming Meng Zicong Li Gengyuan Cai Linjun Hong Zhenfang Wu 
supported by the National Key Research and Development Program of China(2021YFD1301103);the National Natural Science Foundation of China(31802033);the Guangdong Provincial Key Area Research and Development Program(2022B0202090002);the Guangdong Basic and Applied Basic Research Foundation(2022A1515011131,2023A1515030193);the Guangdong Provincial Promotion Project on Preservation and Utilization of Local Breed of Livestock and Poultry(2018143).
Dynamic crosstalk between the embryo and mother is crucial during implantation.Here,we comprehensively profile the single-cell transcriptome of pig peri-implantation embryos and corresponding maternal endometrium,iden...
关键词：endometrial remodeling ExtraCellTalk IMPLANTATION maternal-foetal crosstalk TROPHOBLAST 
Human CD56^(+)CD39^(+) dNK cells support fetal survival through controlling trophoblastic cell fate: immune mechanisms of recurrent early pregnancy loss被引量：1
《National Science Review》2024年第6期122-138,共17页Wentong Jia Liyang Ma Xin Yu Feiyang Wang Qian Yang Xiaoye Wang Mengjie Fan Yan Gu Ran Meng Jian Wang Yuxia Li Rong Li Xuan Shao Yan-Ling Wang 
supported by grants from the National Key Research and Development Program of China(2022YFC2702400,2021YFC2700303,2022YFC2702500 and2022YFA1103601);the National Natural Science Foundation of China(82192872).
Decidual natural killer(dNK)cells are the most abundant immune cells at the maternal-fetal interface during early pregnancy in both mice and humans,and emerging single-cell transcriptomic studies have uncovered variou...
关键词：recurrent pregnancy loss CD56^(+)CD39^(+)dNK subset NOG mice adoptive transfer placental trophoblast cell fate M-CSF 
Propylparaben Induces Reproductive Toxicity in Human Extravillous Trophoblast Cells via Apoptosis and Cell Cycle Pathways
《Environment & Health》2024年第5期301-310,共10页Yifen Guo Yingao Yang Zixuan Zhou Changyuan Zhao Yanchun Li Huanying Zhou Shuyue Ren Yan Gu Zhixian Gao 
supported by Tianjin Key Laboratory of Risk Assessment and Control Technology for Environment and Food Safety,Tianjin Institute of Environmental and Operational Medicine.
Parabens(PBs),especially propylparaben,commonly used in consumer products,pose environmental and health concerns.This study explored propylparaben’s cytotoxicity on HTR-8/SVneo human trophoblast cells,revealing signi...
关键词：PROPYLPARABEN HTR-8/SVneo cells TROPHOBLAST APOPTOSIS RNA-seq 
Microcarriers promote the through interface movement of mouse trophoblast stem cells by regulating stiffness被引量：2
《Bioactive Materials》2023年第10期196-205,共10页Zili Gao Jia Guo Bo Gou Zhen Gu Tan Jia Sinan Ma Liyuan Jiang Wenli Liu Lixun Zhou Qi Gu 
supported by National Natural Science Foundation of China(T2222029 and U21A20396);Strategic Priority Research Program of Chinese Academy of Sciences(XDA16020802);CAS Project for Young Scientists in Basic Research(YSBR-012);CAS Engineering Laboratory for Intelligent Organ Manufacturing(KFJ-PTXM-039).
Mechanical force is crucial in the whole process of embryonic development.However,the role of trophoblast mechanics during embryo implantation has rarely been studied.In this study,we constructed a model to explore th...
关键词：BIOMECHANICS MICROCARRIERS Embryo implantation Cell migration 
The transcriptional activator Klf5 recruits p300-mediated H3K27ac for maintaining trophoblast stem cell pluripotency
《Journal of Molecular Cell Biology》2023年第7期31-44,共14页Chengli Dou Linhui Wu Jingjing Zhang Hainan He Tian Xu Zhisheng Yu Peng Su Xia Zhang Junling Wang Yi-Liang Miao Jilong Zhou 
This work was supported by the National Natural.Science Foundation of China(31970822 and 31902161);the Key Research and Development Program of Hubei Province(2021BBA221 and 2022BCE002);the Fundamental Research Funds for the Central Universities(2662022DKPY001);the Major Project of Hubei Hongshan Laboratory(2021hszdo03)。
The effective proliferation and differentiation of trophoblast stem cells(TSCs)is indispensable for the development of the placenta,which is the key to maintaining normal fetal growth during pregnancy.Kruppel-like fac...
关键词：Klf5 trophoblast stem cells SELF-RENEWAL chromatin accessibility P300 H3K27ac 
Focal adhesion kinase signaling is necessary for the hydrogen sulfide-enhanced proliferation,migration,and invasion of HTR8/SVneo human trophoblasts
《Reproductive and Developmental Medicine》2023年第2期75-82,共8页Xian-Li Wang Jing Tang 
special clinical research projects of Shanghai Municipal Health Commission(202140065);Shanghai Rising Stars of Medical Talent Youth Development Program(AB83030002019004)
Objective:Hydrogen sulfide(H_(2)S)has been elucidated that it promotes migration and invasion in human placenta trophoblasts.However,the signaling pathway underlying H_(2)S-based regulation of trophoblasts remains unk...
关键词：Hydrogen sulfide TROPHOBLAST PROLIFERATION MIGRATION INVASION Focal adhesion kinase signaling 
UCK2 promotes the proliferation,migration,and invasion of trophoblast cells in preeclampsia by activating the STAT3 pathway被引量：1
《BIOCELL》2023年第4期837-847,共11页WEI XIA NING YANG XIAOYAN FENG TING XIN YONGLE JING YUMING LI CHENGZHI LU 
supported by“Heart Health Research Fund,”Special Fund for Cardiovascular Disease Development of China,China International Medical Foundation(Grant No.Z-2019-42-1908-3),Tianjin Key Medical Discipline(Specialty)Construction Project,and the Young Talents Training Program of Tianjin First Central Hospital.
Background:Preeclampsia(PE),characterized by hypertension and proteinuria,leads to serious maternal and infant complications.Uridine-cytidine kinase 2(UCK2)belongs to the UCK family,a class of enzymes that catalyzes t...
关键词：UCK2 PREECLAMPSIA STAT3 TROPHOBLAST INVASION 
Updates in the Diagnosis of Gestational Trophoblast Disease
《Health》2023年第1期48-58,共11页Maira de Lima Oliveira Mota Marcela Curvêllo Beltrão Elizabeth Bacha Eduardo Fonseca Mascarenhas Filho Maísa Mendonça de Jesus Nelson Henriky Felix Mascarenhas Tallys Leandro Barbosa da Silva Maria Fernanda Telles Pires de Souza Victoria de Oliveira Carmo Borges Séfora Maria Fragoso Braga 
GTD (Gestational Trophoblastic Disease) is a pathology that encompasses benign and malignant clinical forms, affects women of childbearing age, has a variable incidence and is more frequent in developing or underdevel...
关键词：DIAGNOSIS Gestational Trophoblastic Disease UPDATES 
全选清除导出
共7页<1234567>
检索报告 对象比较 聚类工具 使用帮助 返回顶部