This work was supported in part by the National NaturalScience Foundation of China(31430054,31320103904,31621002,31671405,31601097,91854203,91753000,and91853115);'Strategic Priority Research Program'of the ChineseAcademy of Sciences(XDB19000000);the National Key Researchand Development Program of China(2017YFA0503600 and2016YFA-0100500);MOE Innovative Team project(IRT_17R102);and the US National Institutes of Health(CA164133,DK56292,and DK115812).
Error-free cell division depends on the accurate assembly of the spindle midzone from dynamic spindle microtubules to ensure chromatid segregation during metaphase-anaphase transition.However,the mechanism underlying ...
We are grateful to Prof. Yunyu Shi for support;to Dr Hongtao Yu for reagents and Drs Guo-Qiang Chen for input. We thank all the members of our laboratories for discussion and Qiaoqiao Zhang for help on several BubRI mutant constructs;initiated by the chemical biology grant PGX-2 from the ProteoGenomics Research Laboratory;supported in part by the National Key Research and Development Program of China (2017YFA0503600, 2017YFA0504901, 2016YFA0100500);National Natural Science Foundation of China (31320103904, 31430054, 91313303, 31621002, 31301120, 91854203, 91853115, 91753000, 31671405, 31470792, 31601097, 21672201, 31600607, and B1661138004);Strategic Priority Research Program' of the Chinese Academy of Sciences (XDB19000000 and XDB08030102);MOE Innovative team (IRT_17R102).
Error-free mitosis depends on accurate chromosome attachment to spindle microtubules, powered congression of those chromosomes, their segregation in anaphase, and assembly of a spindle midzone at mitotic exit. The cen...
This work is supported by the Liver Disease Prevention and Treatment Research Foundation of Taiwan to M.Z.W.;by the Intramural Pro-gram of the U.S.National Cancer Institute to J.L..
Enhancer of rudimentary homolog(ERH)is a small,highly conserved protein among eukaryotes.Since its discovery nearly 20 years ago,its molecular function has remained enigmatic.It has been implicated to play a role in t...
Acknowledgments We thank members of our groups for insightful discussion during the course of this study. This work was initiated by the chemical biology grant PGX-t from the Proteomics Research Laboratory, and supported in part by Chinese Academy of Sciences Grants (KSCX2-YW-H-10 and KSCX2-YW-R195), 973 projects (2002CB713700; 2010CB912103), National Natural Science Foundation of China (90913016), and Georgia Cancer Coalition Eminent Scholar Award.
Dear Editor, Chromosome movements during mitosis are orches- trated primarily by the interaction of spindle microtu- bules with the kinetochore [1], the site for attachment of spindle microtubules to the centromere. ...