CHOLINERGIC

作品数：112被引量：321H指数：9
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相关机构：北京大学首都医科大学附属北京朝阳医院中国医学科学院北京协和医学院中国中医研究院更多>>
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Kai Xin San ameliorates scopolamine-induced cognitive dysfunction被引量：13
《Neural Regeneration Research》2019年第5期794-804,共11页Yu-Min Xu Xin-Chen Wang Ting-Ting Xu Hong-Ying Li Shang-Yan Hei Na-Chuan Luo Hong Wang Wei Zhao Shu-Huan Fang Yun-Bo Chen Li Guan Yong-Qi Fang Shi-Jie Zhang Qi Wang Wei-Xiong Liang 
supported by the National Natural Science Foundation of China,No.81473740,81673627,81673717(to QW);Guangzhou Science Technology and Innovation Commission Technology Research Projects,China,No.2018050100(to QW);the Foundation for Characteristic Innovation of Educational Commission of Guangdong Province,China,Grant No.2016KTSCX011(to SHF);the Open Tending Project for Construction of High-Level University,Guangzhou University of Chinese Medicine,China,No.34 and 118,2017(to SHF);the Technology Platform of Clinical Trials on New Traditional Medicine,China,No.2012ZX09303009-003(to WXL);the Technology Platform of Clinical Evaluation on New Traditional Medicine,China,No.2008ZX09312-021(to WXL)
Kai Xin San(KXS, containing ginseng, hoelen, polygala, and acorus), a traditional Chinese herbal compound, has been found to regulate cognitive dysfunction; however, its mechanism of action is still unclear. In this s...
关键词：Kai Xin SAN cognitive DYSFUNCTION SCOPOLAMINE hydrobromide neuroprotection oxidative stress SYNAPTIC DYSFUNCTION apoptosis CHOLINERGIC system DYSFUNCTION DONEPEZIL neural regeneration 
NP-5 Alleviating Effects of Osthol on Scopolamine-Induced Cholinergic Impairments in Mice
《神经药理学报》2018年第4期104-104,共1页LI Ming-liang LI Ying RONG Da-you TIAN Chun-yu MI Ya-xin HOU Xue-qin 
Objective:To investigate the effect of osthol on the central cholinergic nerve circuit in AD model mouses,,which were established by intraperitoneal injection of scopolamine.Methods:60 health female rats were randomly...
关键词：OSTHOL Central CHOLINERGIC Alzheimer’s disease OXIDATIVE stress 
Neuroprotection of N-benzylcinnamide on scopolamine-induced cholinergic dysfunction in human SH-SY5Y neuroblastoma cells被引量：2
《Neural Regeneration Research》2017年第9期1492-1498,共7页Nicha Puangmalai Wipawan Thangnipon Rungtip Soi-ampornkul Nirut Suwanna Patoomratana Tuchinda Saksit Nobsathian 
supported by a joint Mahidol University and The Thailand Research Fund(TRF)grant(IRG5780009);TRF Royal Golden Jubilee Ph.D.Program(grant No.PHD/0175/2552);the Office of the Higher Education Commission,Ministry of Education,Thailand
Alzheimer＇s disease, a progressive neurodegenerative disease, affects learning and memory resulting from cholinergic dysfunction. Scopolamine has been employed to induce Alzheimer＇s disease-like pathology in vivo an...
关键词：Alzheimer＇s disease ACETYLCHOLINE apoptosis acetylcholinesterase inhibitor oxidative stress N-benzylcinnamide natural product SCOPOLAMINE neuronal regeneration 
ACOUSTIC STARTLE RESPONSE AFFECTED BY AGING AND CHOLINERGIC NEUROTRANSMITTERS被引量：1
《Journal of Otology》2014年第2期73-80,共8页Anna Hansen SUN Wei 
The acoustic startle response has been used to evaluate tinnitus and hyperacusis in animal models. Gap induced prepulse in- hibition of the acoustic startle reflex （gap-PPI） is affected by tinnitus and loudness chan...
关键词：startle reflex HYPERACUSIS ACETYLCHOLINE SCOPOLAMINE 
Effect of Kangshuai Yizhi Formula Ⅰ (抗衰益智方Ⅰ) on Learning and Memory Dysfunction Induced by Scopolamine in Mice被引量：1
《Chinese Journal of Integrative Medicine》2010年第3期252-257,共6页韦佳 陆大祥 戚仁斌 王华东 江雪华 
Supported by Special Fund for Doctor Discipline Research of Ministry of Education(No.20060559003);Key Programs for Science and Technology Development of Guangzhou (2008J1-C181)
Objective：To evaluate the improvement of Kangshuai Yizhi FormulaⅠ（抗衰益智方Ⅰ,KYFⅠ）on the learning and memory dysfunction in mice,and on the mechanism of the hippocampal cholinergic system and the nervous system...
关键词：dysmnesic CHOLINERGIC monoamine neurotransmitters monoamine oxidase 
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