Ten workers from a cyclotron unit have beenaccidentally exposed to Osmium tetroxide emanations during a fewhours.In vitro,Osmium tetroxide forms an irreversible bindingwith thymidine without apparently disturbance in ...
Effect of four DNA repair inhibitors on the frequencyof chromosome aberration induced by cadmium chloridewas investigated.3-Aminobenzamide (3 AB), inhibitor of poly(ADP-ribose) polymerase,increased the frequency ofind...
H F M C (copolymer of hydroxythyl methacrylate) is a kindof high polymers which could be used for male contraception byinjecting it into the deferent ducts.To evaluate the poten-tial genetic risk of H F M C,521 karyot...
A total of 56 inhabitants was selected and studied in pollutedarea,average age of 39.8 years,10 in controlled area,averageage of 41.0 years.Inhabitants examined in polluted area weredivided into four groups according ...
In this study,the chromosome aberrations ofcultured peripheral blood cells of 28 untreatedesophageal cancer and 25 normal individuals weretaken.PMA-induced CA was compared with spontane-ous one.The peripheral blood wh...
In the Ames,when trichtoromethance’s concentration was50ug/plate,the induced revertible bacteria was three timesthan negative control guoup in the strain TA100 with -S, and+S Mix.When trichloromethance’s concentrati...
Using SCE,a sensitive indicator in mutagenicitytesting,-as a marker,we observed the linkageamong MMC,SCE and Chinese medicine—Lycium inthe elderly.The results showed that there is
The Chinese medicine compound Shou Wutested for mutagenic and antimutagenicactivities by two different geneticsystems.It was chromosome aberration(CA) and micronucleus of polychromaticerythrocyte (MNPCE) in mouse.
After actively cycling lymphocytes of five can-cer patients and five normal persons were treatedwith mitomycin C (MMC) in five doses (0,0.025,0.050.1,0.2μg/ml) for 24 hours,chromosome aberrationfrequencies (CAF) and ...
The chromosome rearrangement frequenties(CRF)induced by mitomycin C and thiotepa,those wereused in four doses respectively,were observed inthe blood samples of eight donors.It was foundthat there were negative linear ...