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PROTECT: 作品数：547被引量：718H指数：13; 导出分析报告; 相关领域：医药卫生更多>>; 相关作者：龚建光刘琳金娟侯昕何强更多>>; 相关机构：浙江省人民医院安徽医科大学西北工业大学大连医科大学更多>>; 相关期刊：更多>>; 相关基金：国家自然科学基金国家重点基础研究发展计划中国博士后科学基金高等学校学科创新引智计划更多>>

Human neural stem cell-derived extracellular vesicles protect against ischemic stroke by activating the PI3K/AKT/mTOR pathway: 《Neural Regeneration Research》2025年第11期3245-3258,共14页Jiayi Wang Mengke Zhao Dong Fu Meina Wang Chao Han Zhongyue Lv Liang Wang Jing Liu; supported by the National Nature Science Foundation of China,No.81471308(to JL);the Innovative Leading Talents of Liaoning Province,No.XLYC1902031(to JL);Science and Technology Projects in Liaoning Province,No.2022-BS-238(to CH);Young Top Talents of Liaoning Province,No.XLYC1907009(to LW);Dalian Science and Technology Innovation Fund,No.2018J11CY025(to JL)。; Human neural stem cell-derived extracellular vesicles exhibit analogous functions to their parental cells,and can thus be used as substitutes for stem cells in stem cell therapy,thereby mitigating the risks of stem ce...; 关键词：behavior EXOSOME extracellular vesicles ischemic stroke mammalian target of rapamycin(mTOR) middle cerebral artery occlusion neural stem cells neuronal apoptosis phosphoinositide 3-kinase(PI3K) protein kinase B(AKT)

Goji berry-derived phenylpropionyl phenylethylamine derivatives protect against ethanol-induced hepatic damage: 《Food Science and Human Wellness》2025年第3期1139-1147,共9页Zhengqun Zhou Zhaodi Che Jiancong Mai Rui Zhang Zhihui Luo Yifang Li Kwokfai So Jia Xiao Xinsheng Yao Hao Gao; funded via National Natural Science Foundation of China(81925037,82321004,U22A20371,and 82273801);Guangdong Major Project of Basic and Applied Basic Research(2023B0303000026);Guangdong International Science and Technology Cooperation Base(2021A0505020015);Innovative and Research Teams Project of Guangdong Higher Education Institution(2021KCXTD001);Guangdong Basic and Applied Basic Research Foundation(2022A1515012071);Young Elite Scientists Sponsorship Program by China Association of Chinese Medicine(2021-QNRC2-B21);Guangdong-Hong Kong-Macao Universities Joint Laboratory for the Internationalization of Traditional Chinese Medicine(2023LSYS002);Guangzhou Key Laboratory of Traditional Chinese Medicine&Disease Susceptibility(2024A03J090);Science and Technology Program of Guangzhou(201707010414,202201020066,and 2024A04J9955)。; Goji berry is a famous edible and medicinal substance around the world.In this research,15 phenylpropionyl phenylethylamine derivatives(1-15),in cluding one new compound(1),were separated and identified from g oji ber...; 关键词：Goji berry Lycium barbarum Phenylpropionyl phenylethylamine derivatives Antioxidant activity He patoprotective effect

Hypoxia-preconditioned bone marrow-derived mesenchymal stem cells protect neurons from cardiac arrest-induced pyroptosis被引量：1: 《Neural Regeneration Research》2025年第4期1103-1123,共21页Xiahong Tang Nan Zheng Qingming Lin Yan You Zheng Gong Yangping Zhuang Jiali Wu Yu Wang Hanlin Huang Jun Ke Feng Chen; supported by the Natural Science Fund of Fujian Province,No.2020J011058(to JK);the Project of Fujian Provincial Hospital for High-level Hospital Construction,No.2020HSJJ12(to JK);the Fujian Provincial Finance Department Special Fund,No.(2021)848(to FC);the Fujian Provincial Major Scientific and Technological Special Projects on Health,No.2022ZD01008(to FC).; Cardiac arrest can lead to severe neurological impairment as a result of inflammation,mitochondrial dysfunction,and post-cardiopulmonary resuscitation neurological damage.Hypoxic preconditioning has been shown to impr...; 关键词：bone marrow–derived mesenchymal stem cells cardiac arrest cardiac resuscitation hypoxic preconditioning liver isoform of phosphofructokinase mitochondria NEUROINFLAMMATION oxidative stress PYROPTOSIS reactive oxygen species

Defining Their Future LA's Little Tokyo looks for ways to preserve and protect its community: 《空中英语教室(高级版.彭蒙惠英语)》2025年第4期24-26,45,46,共5页Thomas Curwen; In Little Tokyo,the past and the future have long been at odds.Less than a month after the,iconic Suehiro Cafe closed its 1st Street location-evicted after nearly 40 years-community leaders gathered,shovels in hand,to...; 关键词：CORPORATION TOKYO breaking

Rabies virus-based oral and inactivated vaccines protect minks against SARS-CoV-2 infection and transmission: 《Journal of Integrative Agriculture》2025年第3期1198-1211,共14页Hong Huo Shuang Xiao Jinming Wang Xijun Wang Jinying Ge Gongxun Zhong Zhiyuan Wen Chong Wang Jinliang Wang Han Wang Xijun He Lei Shuai Zhigao Bu; supported by the National Key Research and Development Program of China(2021YFC2301700);the Natural Science Foundation of Heilongjiang Province,China(YQ2022C040)。; Minks are highly susceptible to SARS-CoV-2,and have transmitted SARS-CoV-2 to humans.Oral immunization is one of the most promising strategies to prevent SARS-CoV-2 infection and transmission in minks.Here,we generate...; 关键词：SARS-CoV-2 rabies virus oral vaccine inactivated vaccine MINK

Azimuth-based antenna group delay variation modeling for dual-frequency multi-constellation GBAS: 《Chinese Journal of Aeronautics》2025年第2期370-380,共11页Yuan LIU Yanbo ZHU Kun FANG Zhipeng WANG; the National Key Research and Development Program of China(No.2023YFB3907001);the financial support from the National Natural Science Foundation of China(Nos.62371029,U2233217 and 62101019);the Civil Aviation Security Capacity Building Fund Project of China(Nos.CAAC Contract 2021(77)and CAAC Contract 2022(110)).; Antenna Group Delay Variation(AGDV)is a hardware error source that affects the performance of Dual-Frequency Multi-Constellation(DFMC)Ground-based Augmentation System(GBAS),and these errors are difficult to distinguis...; 关键词：Antenna Group Delay Variation(AGDV) Ground-based Augmentation System(GBAS) Integrity Vertical protection level NAVIGATION

KDM2A and KDM2B protect a subset of CpG islands from DNA methylation: 《Journal of Genetics and Genomics》2025年第1期39-50,共12页Yuan Liu Ying Liu Yunji Zhu Di Hu Hu Nie Yali Xie Rongrong Sun Jin He Honglian Zhang Falong Lu; supported by the National Natural Science Foundation of China(32070607);the National Key Research and Development Program of China(2020YFA0804000);the CAS Project for Young Scientists in Basic Research(YSBR-012).; In the mammalian genome,most CpGs are methylated.However,CpGs within the CpG islands(CGIs)are largely unmethylated,which are important for gene expression regulation.The mechanism underlying the low methylation levels...; 关键词：KDM2A KDM2B CpG island DNA methylation H3K36me2 DEMETHYLATION Embryonic stem cell

Valorization of Ubiquitous Plant Species Used as Food Packaging in Benin: A Sustainable Solution to Improve Quality of Life and Protect the Environment: 《American Journal of Plant Sciences》2025年第1期51-63,共13页Joli Prince Mintognissè Fossou Yann Christie Sissinto Adjovi Ulrich Hilarion Ahéhéhinnou Frida Tovo Sèna Emmanuelle Dédéhou; Vegetal leaves play a significant role in the daily lives of populations in developing countries. This study aimed to highlight the plant species used as food packaging in southern Benin. A survey questionnaire was ad...; 关键词：Socio-Ethnobotanical Surveys Food Items Secondary Metabolites Bioactive Natural Substances Phytochemical Screening

WIPO Report:China's TISC Institutions Continually Protect Innovators: 《中国专利与商标》2024年第4期88-88,共1页; The World Intellectual Property Organization(WIPO)released the 2023 Technology and Innovation Support Centers(TISCs)report recently.The report shows that by the end of 2023,WIPO had established 1,494 TISCs in 93 count...; 关键词：WIPO INSTITUTION SERVICE

核心素养导向下大观念引领的小学英语单元整体教学研究——以Unit 7 Protect the Earth为例: 《英语教师》2024年第23期147-149,共3页王敏; 自核心素养理念被提出后,为了适应英语教育的转变趋势,小学英语课堂教学模式逐渐由知识导向转向素质导向,在这一基础上提出基于大观念和单元整体教学的小学英语教育改进策略。阐述英语学科大观念与单元整体教学之间的关联,并分析核心素...; 关键词：核心素养大观念小学英语单元整体教学

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