CIRRHOSIS

作品数:1411被引量:7237H指数:35
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相关领域:医药卫生更多>>
相关作者:陆忠华于亚杰陈菊娣居朝霞周美芳更多>>
相关机构:中华医学会解放军第302医院香港大学复旦大学更多>>
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相关基金:国家自然科学基金国家重点基础研究发展计划国家高技术研究发展计划北京市自然科学基金更多>>
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Role of astrocytes and microglia in hepatic encephalopathy associated with advanced chronic liver disease:lessons from animal studies
《Neural Regeneration Research》2025年第12期3461-3475,共15页Wouter Claeys Anja Geerts Lien Van Hoecke Christophe Van Steenkiste Roosmarijn E.Vandenbroucke 
supported by grants from the Research Foundation–Flanders(11A6420N,1268823N to WC and LVH);a FWO Junior Research Project Grant(G055121N to REV);VIB.AG is a senior clinical researcher of the Research Foundation–Flanders(1805718N)。
Hepatic encephalopathy,defined as neuropsychiatric dysfunction secondary to liver disease,is a frequent decompensating event in cirrhosis.Its clinical impact is highlighted by a notable increase in patient mortality r...
关键词:AMMONIA ASTROCYTES CIRRHOSIS hepatic encephalopathy MICROGLIA NEUROINFLAMMATION osmotic stress oxidative stress systemic inflammation 
Cirrhosis after pancreaticoduodenectomy for pancreatic cancer
《Hepatobiliary & Pancreatic Diseases International》2025年第2期232-236,共5页Rui Su Hong-Na Liu Yu-Bo Wang Yun Bai 
To the Editor:Nonalcoholic fatty liver disease(NAFLD)is a clinicopathological syndrome characterized by excessive intracellular lipid accumulation in hepatocytes,not attributed to alcohol,viral infections,or other wel...
关键词:IMPAIRED NAFLD HEPATIC 
Hypochloremia is an underutilised prognostic marker in patients with advanced liver cirrhosis and liver failure
《World Journal of Hepatology》2025年第3期42-49,共8页Jinit R Soni Sudheer Marrapu Ramesh Kumar 
Patients with advanced liver cirrhosis and liver failure frequently experience abnormalities in their serum electrolyte levels.In such patients,hyponatremia has been identified as a predictor of poor outcomes.However,...
关键词:CHLORIDE Hypochloremia Liver failure CIRRHOSIS HYPONATREMIA PROGNOSIS 
Establish and validate an artificial neural networks model used for predicting portal vein thrombosis risk in hepatitis B-related cirrhosis patients
《World Journal of Hepatology》2025年第3期90-101,共12页Pei-Pei Meng Fei-Xiang Xiong Jia-Liang Chen Yang Zhou Xiao-Li Liu Xiao-Min Ji Yu-Yong Jiang Yi-Xin Hou 
Supported by The Beijing Hospitals Authority Youth Programme,No.QMl220201802.
BACKGROUND The portal vein thrombosis(PVT)can exacerbate portal hypertension and lead to complications,increasing the risk of mortality.AIM To evaluate the predictive capacity of artificial neural networks(ANNs)in qua...
关键词:Machine learning Portal vein thrombosis RISK Hepatitis B-related cirrhosis 
Improving radiomics-based models for esophagogastric variceal bleeding risk prediction in cirrhotic patients
《World Journal of Gastroenterology》2025年第11期212-215,共4页Arunkumar Krishnan 
A recent study by Peng et al developed a predictive model for first-instance secondary esophageal variceal bleeding in cirrhotic patients by integrating clinical and multi-organ radiomic features.The combined radiomic...
关键词:Artificial intelligence CIRRHOSIS Radiomics Esophagogastric variceal bleeding Esophageal varices BLEEDING 
Correlations of three scoring systems with the prognosis of patients with liver cirrhosis complicated with sepsis syndrome
《World Journal of Gastrointestinal Surgery》2025年第3期150-160,共11页Li-Nan Liu Yu-Fei Chang Hui Wang 
BACKGROUND Severe symptoms associated with sepsis syndrome(SS)are considered a severe threat,which not only increases therapeutic difficulty but also causes a prognostic mortality rate.However,at present,few related s...
关键词:Model for end-stage liver disease Sequential organ failure assessment Modified early warning score CIRRHOSIS Sepsis syndrome 
Platelet activation relieves liver portal hypertension via the lymphatic system though the classical vascular endothelial growth factor receptor 3 signaling pathway
《World Journal of Gastroenterology》2025年第10期86-102,共17页Min Chen Jin-Bo Zhao Guang-Bo Wu Zheng-Hao Wu Gu-Qing Luo Zhi-Feng Zhao Chi-Hao Zhang Jia-Yun Lin Hong-Jie Li Xiao-Liang Qi Hai-Zhong Huo Abudukadier Tuersun Qiang Fan Lei Zheng Meng Luo 
Supported by the National Natural Science Foundation of China,No.82100639,No.82200630,and No.81970526;Postdoctoral Scientific Research Foundation of Shanghai Ninth People’s Hospital,Shanghai Jiao Tong University School of Medicine,No.202401023;Clinical Research Program of Ninth People’s Hospital,Shanghai Jiao Tong University School of Medicine,No.JYLJ202124;Shanghai Municipal Commission of Health and Family Planning,No.20244Y0195 and No.20234Y0132;the Fundamental Research Program Funding of Ninth People’s Hospital Affiliated to Shanghai Jiao Tong University School of Medicine,No.JYZZ162;Science Foundation of Xinjiang Uygur Natural Autonomous Region,No.2022D01F17.
BACKGROUND Liver cirrhosis and portal hypertension(PHT)can lead to lymphatic abnormalities and coagulation dysfunction.Because lymphangiogenesis may relieve liver cirrhosis and PHT,the present study investigated the g...
关键词:Portal hypertension CIRRHOSIS LYMPHANGIOGENESIS PLATELETS Vascular endothelial growth factor C 
Burden,stress and depression in caregivers of cirrhosis patients before and after liver transplantation
《World Journal of Transplantation》2025年第2期276-287,共12页Adriano Virches Mariana B Claudino Maria C Miyazaki Eliane T Miyazaki Renato F Silva Rita C Silva Heitor B Farias Neide A Domingos Randolfo Santos Jr Patricia S Fucuta 
BACKGROUND Family caregivers of cirrhosis patients(CPs)often experience burden,stress,and depression.Investigating whether these conditions improve following the patient undergoing liver transplantation(LT)is crucial,...
关键词:Mental disorders Caregiver burden Psychological stress Depressive disorder Chronic disease Liver cirrhosis Transplant recipients Liver transplantation 
Limitations and enhancement opportunities for variceal rebleeding prediction model in patients with cirrhosis
《World Journal of Gastroenterology》2025年第8期161-163,共3页Guang-Bin Chen Fei Wu Rong-Mei Tang Long-Jiang Chen 
A multicenter study recently published introduced a novel prognostic model for predicting esophagogastric variceal rebleeding after endoscopic treatment in patients with cirrhosis.The model incorporated six readily av...
关键词:Prognostic model Liver cirrhosis Variceal rebleeding Risk stratification Endoscopic treatment Portal hypertension Clinical prediction 
Evaluating the scope of human leukocyte antigen polymorphisms influencing hepatitis B virus-related liver cancer and cirrhosis through multi-clustering analysis
《World Journal of Gastroenterology》2025年第7期156-159,共4页Shi Li Yue Xi Xue-Ying Dong Wen-Bin Yuan Jing-Feng Tang Ce-Fan Zhou 
Supported by National Natural Science Foundation of China,No.32270768,No.82273970,No.32070726,and No.82370715;National Key R&D Program of China,No.2023YFC2507904;the Innovation Group Project of Hubei Province,No.2023AFA026.
Hepatitis B virus remains a major cause of cirrhosis and hepatocellular carcinoma,with genetic polymorphisms and mutations influencing immune responses and disease progression.Nguyen et al present novel findings on sp...
关键词:Hepatitis B virus Gene polymorphisms Multi-clustering analysis Genetic markers Personalized medicine Clinical implications 
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