supported by grants from the National Natural Science Foundation of China(No.31500748);the CAMS Innovation Fund for Medical Sciences(No.2017-I2M-3-022).
Viroids,the smallest known infectious agents,were initially discovered in plants[1],and have caused significant agricultural diseases[2–4].Recently,viroids have been identified in fungi[5–7]and bacteria[8],but none ...
BACKGROUND Hepatic metastases are common and difficult to treat after colorectal cancer(CRC)surgery.The predictive value of carcinoembryonic antigen(CEA),cancer antigen(CA)125 and CA19-9 combined tests for liver metas...
supported by the Provincial Key R&D Program of Zhejiang Province(No.2021C03125);National Natural Science Foundation of China(No.82373415 and No.82302489);Beijing Xisike Clinical Oncology Research Foundation(No.Y-tongshu2021/ms-0003).
According to the latest global cancer statistics,colorectal cancer(CRC)is the most common malignancy of the digestive system and the second most lethal among all cancer types(1).In China,CRC is the second most prevale...
supported by a grant from the National Natural Science Foundation of China(No.72074011)
To the Editor:The colorectal cancer(CRC)is the fourthmost common cause of cancer deaths in China that was treated as a public health threat,accounting for approximately 10%of all the cancer-caused mortalities each yea...
Objective To investigate the effects of lncRNA SNHG11 on proliferation,migration,invasion and apoptosis of colorectal cancer cancer cells and possible mechanisms.Methods qRT-PCR was performed to detect the expression ...
In a recent study published in Nature,Zepeda-Rivera et al.1 discovered that one distinct clade of Fusobacterium nucleatum animalis(Fna)dominates the colorectal cancer(CRC)tumor niche.The work unravels a more precise u...
Objective To evaluate the participation rate and detection of colorectal neoplasms based on annual fecal immunochemical testing (FIT) for three consecutive years in a population-based colorectal cancer screening progr...
Approximately 20%of colorectal cancer(CRC)patients present with metastasis at diagnosis.Among Stage I-III CRC patients who undergo surgical resection,18%typically suffer from distal metastasis within the first three y...
Colorectal cancer(CRC)with mismatch-repair deficiency(dMMR)is a distinct molecular subgroup of tumors that is characterized by a diminished capacity to correct base-pair mismatches in DNA,which leads to changes in mic...
supported by The Wells Center for Pediatric Research,Riley Children’s Foundation,Jeff Gordon Children’s Foundation,and IU Simon Cancer Center.
Colorectal cancer(CRC)is the second most deadly adult cancer in men and women combined,accountable 9.2%of all cancer deaths.^(1)Drug resistance to chemotherapies,such as 5-FU-related regimens,remains a major cause of ...