CIRCULAR

作品数:1019被引量:2330H指数:18
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相关领域:理学更多>>
相关作者:杨宏宇林文松朱睿张强张强更多>>
相关机构:山东大学东南大学哈尔滨医科大学中国科学院更多>>
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相关基金:国家自然科学基金国家重点基础研究发展计划中国博士后科学基金北京市自然科学基金更多>>
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Potential mechanisms of non-coding RNA regulation in Alzheimer's disease
《Neural Regeneration Research》2026年第1期265-280,共16页Yue Sun Xinping Pang Xudong Huang Dinglu Liu Jingyue Huang Pengtao Zheng Yanyu Wei Chaoyang Pang 
Alzheimer's disease,a progressively degenerative neurological disorder,is the most common cause of dementia in the elderly.While its precise etiology remains unclear,researchers have identified diverse pathological ch...
关键词:Alzheimer's disease biomarkers circular RNA long non-coding RNA microRNA ncRNA regulation NEURODEGENERATION non-coding RNA PATHOGENESIS therapeutic targets 
Computational approaches for circRNA-disease association prediction:a review
《Frontiers of Computer Science》2025年第4期99-113,共15页Mengting NIU Yaojia CHEN Chunyu WANG Quan ZOU Lei XU 
supported by the National Natural Science Foundation of China(Grant Nos.62231013,62201129,62303328,62302341,62271329,62372332);the National Key R&D Program of China(2022ZD0117700);the National funded postdoctoral researcher program of China(GZC20230382);the Shenzhen Polytechnic University Research Fund(6024310027K,6022310036K,6023310037K);the Key Field of Department of Education of Guangdong Province(2022ZDZX2082);the Special Science Foundation of Quzhou(2023D036).
Circular RNA(circRNA)is a covalently closed RNA molecule formed by back splicing.The role of circRNAs in posttranscriptional gene regulation provides new insights into several types of cancer and neurological diseases...
关键词:circular RNA disease association prediction machine learning data mining deep learning 
Coding circular RNA in human cancer
《Genes & Diseases》2025年第3期194-204,共11页Yuan Lin Yawen Wang Lixin Li Kai Zhang 
supported by the National Natural Science Foundation of China(No.81802406);Shandong Provincial Natural Science Foundation of China(No.ZR2021MH045,ZR2020LZL009,ZR2019BH061,ZR2021MH225);Special Funds for Scientific Research on Breast Diseases of Shandong Medical Association of China(No.YXH2021ZX058).
circular RNA (circRNA) is a covalently closed single-stranded RNA that lacks 5’ and 3’ends and has long been considered a noncoding RNA. With the development of high-throughputsequencing and bioinformatics technolog...
关键词:Cancer Cap-independent Circular RNA Protein-coding circRNA TRANSLATION 
Non-coding RNAs in adipose-derived stem cell exosomes:Mechanisms,therapeutic potential,and challenges in wound healing
《World Journal of Stem Cells》2025年第4期6-19,共14页Jian Rong Yao-Yao Li Xin Wang Jia-Ning Wang Mei Song 
Supported by the Intra-Hospital Project of No.940 Hospital of the Joint Logistics Support Force of the Chinese People’s Liberation Army,No.2021yxky016.
The treatment of complex wounds presents a significant clinical challenge due to the limited availability of standardized therapeutic options.Adipose-derived stem cell exosomes(ADSC-Exos)are promising for their capabi...
关键词:Adipose-derived stem cell exosomes Wound healing MICRORNAS Long noncoding RNAs Circular RNAs 
Slope stability prediction of circular mode failure by machine learning models based on Bayesian Optimizer
《Journal of Mountain Science》2025年第4期1482-1498,共17页Mohammad Hossein KADKHODAEI Ebrahim GHASEMI Mohammad Hossein FAZEL 
Assessing the stability of slopes is one of the crucial tasks of geotechnical engineering for assessing and managing risks related to natural hazards,directly affecting safety and sustainable development.This study pr...
关键词:Slope stability Circular failure Machine learning Bayesian optimizer Hybrid models 
Circulating circular RNAs act as potential novel biomarkers for sepsis secondary to pneumonia:a prospective cohort study
《World Journal of Emergency Medicine》2025年第2期144-152,共9页Chunxue Wang Dianyin Yang Yuxin Zhu Qian Yang Tong Liu Xiandong Liu Dongyang Zhao Xiaowei Bao Tiancao Dong Li Shao Lunxian Tang 
supported by grants from the municipal Natural Science Foundation of Shanghai Scientific Committee of China(22ZR1451000 to TL);the peak supporting clinical discipline of Shanghai Health Bureau(2023ZDFC0104 to TL);the key clinical discipline of Shanghai Pudong Health Bureau(PWZxk2022-17 to TL);the clinical peak discipline of Shanghai Pudong Heath Bureau(PWYgf2021-03);the top-notch innovative medical talents of Shanghai Pudong Health Bureau(2025PDWSYCBJ-03 to TL);the leading medical talent project of Shanghai Pudong Heath Bureau(PWR12020-07 to LS)。
BACKGROUND:Circulating biomarkers for sepsis are lacking,and research on circular RNAs(circR NAs)as potential biomarkers of pneumonia-induced sepsis is limited.This study aims to investigate the diagnostic and prognos...
关键词:Circular RNAs BIOMARKER Pneumonia-induced sepsis Diagnosis Prognosis 
Research and Application of Verticality Detection Method for Circular Pier with Equal Section
《Journal of World Architecture》2025年第2期55-60,共6页Zhenbang Lu Yuting Cheng Lisheng Zhao Shi’ao Shi Ming Kou Zihao Peng 
This article presents four techniques for assessing verticality:the plumb line approach,the total station distance technique,the three-point centering method,and the centroid method.Given the significant error associa...
关键词:VERTICALITY Centrality method Synthetic verticality 
Extramural venous invasion in gastric cancer: 9.4T magnetic resonance imaging assessment and circular RNA functional analysis
《World Journal of Gastroenterology》2025年第14期94-105,共12页Cai-Zhen Feng Xin-Yi Gou Yi-Qun Liu Yu-Wei Xin Yin-Li Zhang Hui-Min Zhao Sheng-Cai Wei Nan Hong Yi Wang Jin Cheng 
Supported by The National Natural Science Foundation of China,No.81901819;Peking University People’s Hospital Scientific Research Development Funds,No.RDX2024-08;Beijing Natural Science Foundation,No.7232187.
BACKGROUND Extramural venous invasion(EMVI)is a critical prognostic factor in gastric cancer(GC);however,its detection and underlying molecular mechanisms remain underexplored.AIM To investigate the relationship betwe...
关键词:Gastric cancer Circular RNA Extramural venous invasion Orthotopic mouse model Magnetic resonance imaging Pathology Radiogenomics 
Expression profiling and bioinformatics analysis of serum exosomal circular RNAs in lymph node metastasis of papillary thyroid carcinoma
《Journal of Biomedical Research》2025年第2期155-170,I0001-I0004,共20页Huiyong Peng Zhangwei Zhu Jie Xing Qian Xu Changfeng Man Shengjun Wang Yingzhao Liu Zhengdong Zhang 
National Natural Science Foundation of China (Grant No. 81800698);Jiangsu Provincial Medical Key Discipline Cultivation Unit (Grant No. JSDW202241);Research Project of Jiangsu Commission of Health (Grant No. H2023053);Zhenjiang Science and the Technology Planning Project (Grant Nos. SH2023006and SH2023008)。
Most papillary thyroid carcinoma(PTC) patients have a good prognosis. However, lymph node metastasis(LNM), the most common manifestation of disease progression, is frequently associated with a poor prognosis.Neverthel...
关键词:papillary thyroid carcinoma EXOSOME circular RNA regulatory network lymph node metastasis 
Evaluating the potential of circular grass buffer strips to promote fungal community and soil health in water-limited agroecosystems
《Soil Ecology Letters》2025年第1期25-38,共14页Juan P.Frene Rajan Ghimire Sundar Sapkota Sangamesh V.Angadi 
USDA NIFA(Grant#2020-67019-31155);USDA NRCS(GR0007378);the NMSU Agriculture Experiment Station for financial support of the project.
Climate change has caused high weather variability,affecting crop production in arid and semi-arid regions.Circular buffer strips(CBS)of perennial native grasses can produce crops with less irrigation water while prov...
关键词:dryland agriculture CORN perennial grasses soil microbial communities phospholipid fatty acids 
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