Human cells contain two types of adenosine deaminases(ADA)each with unique properties:ADA1,which is present in all cells where it modulates intracellular functions and extracellular signaling,and ADA2,which is secrete...
supported by the Major Science and Technology Special Projects of Yunnan Province,China (202002AA100009);the Non-profit Central Research Institute Fund of Chinese Academy of Medical Sciences (2021-JKCS-012);the Special Biomedicine Projects of Yunnan Province (202102AA310035);National Natural Science Foundation of China (82104130);Fundamental Research Funds for the Central Universities (3332021072);the Basic Research Projects of Yunnan Province (202101AU070176, 202101AT070286);the Funds for the Training of High-level Health Technical Personnel in Yunnan Province(grant number H-2019063);the Funds for High-level Scientific and Technological Talents Selection Special Project of Yunnan Province(202205AC160015)
Latent varicella-zoster virus(VZV)may be reactivated to cause herpes zoster,which affects one in three people during their lifetime.The currently available subunit vaccine Shingrix^(TM) is superior to the attenuated v...