DIHYDROXYLATION

作品数:11被引量:9H指数:2
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相关领域:理学更多>>
相关作者:张生勇孙晓莉李晓晔刘鹏更多>>
相关机构:第四军医大学更多>>
相关期刊:《Chemical Research in Chinese Universities》《Progress in Natural Science:Materials International》《Frontiers of Environmental Science & Engineering》《Chinese Journal of Chemistry》更多>>
相关基金:国家自然科学基金国家重点基础研究发展计划更多>>
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A newly defined dioxygenase system from Mycobacterium vanbaalenii PYR-1 endowed with an enhanced activity of dihydroxylation of high-molecular-weight polyaromatic hydrocarbons被引量:2
《Frontiers of Environmental Science & Engineering》2020年第1期163-173,共11页Yiquan Wu Ying Xu Ningyi Zhou 
This work is supported by the National Key R&D Program of China(Grant No.2018YFC0309800);National Natural Science Foundation of China(Grant No.31570100);Shanghai Science and Technology Commission Scientific Research Project(No.17JC1403300).
NidA3B3 is a terminal dioxygenase whose favorable substrates are high-molecular-weight polyaromatic hydrocarbons(PAHs)from Mycobacterium vanbaalenii PYR-1,a powerftil PAHs degradation strain.NidA3B3 was reported to in...
关键词:Biodegradation Polyaromatic hydrocarbons BIOTRANSFORMATION Ring-hydroxylating DIOXYGENASE SYSTEM 
Divergent synthesis of four isomers of 6,7-dihydroxy-3,7-dimethyloct-2-enoic acid,esters and evaluation for the antifungal activity被引量:3
《Chinese Chemical Letters》2018年第12期1872-1874,共3页Weiwei Wang Xiaoteng Zhang Yu Zhao Xinlei Liu Zhenhua Zhang Ming'an Wang 
the National Natural Science Foundation of China(Nos.21772229,21172254)for the financial support
The four isomers of 6,7-dihydroxy-3,7-dimethyloct-2-enoic acid 2 were synthesized via the selective direct Sharpless asymmetry dihydroxylation of geraniol as the key step in 35.0%-48.0% overall yields with91.9%-97.7% ...
关键词:6 7-Dihydroxy-3 7-dimethyloct-2-enoic acid Sharpless asymmetry dihydroxylation Antifungal activity 
Tandem intramolecular Diels–Alder/retro-Diels–Alder cycloaddition of 2H-chromen-2-one as dienes with the expulsion of CO_2
《Chinese Chemical Letters》2016年第9期1537-1540,共4页Jian Zhang Jin-Long Wu 
supported by the research grant from the National Natural Science Foundation of China (No. 21172191)
To study the intramolecular Diels-Alder cycloadditon of 2H-chromen-2-one as a diene, a series of chiral N-allyl-N-benzylamides that contain a 2H-chrornen-2-one moiety were designed for the synthesis of benzo[f]isoindo...
关键词:2H-Chromen-2-one Intramolecular Diels-Alder Retro-Diels-Alder Benzo[J]isoindol-1 -one Dihydroxylation 
Design and concise synthesis of gem-difluoromethylenated analogue of 7-epi-castanospermine被引量:3
《Chinese Chemical Letters》2014年第8期1115-1120,共6页Xin-Yi Jiang Xiu-Hua Xu Feng-Ling Qing 
the National Natural Science Foundation of China (Nos. 21272036, 21332010);the National Basic Research Program of China (No. 2012CB21600)
A novel gem-difluoromethylenated castanospermine analogue B was designed and synthesized, starting from 3-bromo-3,3-difluoropropene and L-(-)-malic acid. The key steps involve substitution cyclization reaction and R...
关键词:lndolizidine CASTANOSPERMINE gem-Difluoromethylene CYCLIZATION DIHYDROXYLATION 
A Concise Total Synthesis of Amphidinin B
《Chinese Journal of Chemistry》2013年第1期105-110,共6页Dongdong Wu Jinlong Wu Wei-min Dai 
A concise total synthesis of amphidinin B, a cytotoxic linear dicarboxylic acid associated with amphidinolide T marine macrolides, has been accomplished from the 19-membered cycloalkene intermediates designed for dive...
关键词:amphidinin B CYCLOALKENE DIHYDROXYLATION oxidative cleavage total synthesis 
Enantioselective Dihydroxylation of Alkenes Catalyzed by a PEG-Bound Bi-Cinchona Alkaloid Ligand
《Chinese Journal of Chemistry》2005年第1期68-70,共3页杨细文 刘汉泉 徐明华 林国强 
Study on the Synthesis of Metabolite CM2 of Clausenamide被引量:1
《Chinese Chemical Letters》2003年第4期338-340,共3页Xing Zhou LI Ke Mei WU Liang HUANG 
This work was supported by the National Natural Science Foundation of China. ( No.29790121)
Synthesis of the optically active metabolite of clausenamide CM2 (3, 5-dihydroxy- 5-(a-hydroxylbenzyl)-1-methyl-4-benzylpyrrolidin-2-one) from 3-O-acetyl- clausenamide was described.
关键词:METABOLITE CLAUSENAMIDE DEHYDRATION DIHYDROXYLATION deacylation. 
Facile Syntheses of (6S)-6-Fluoroshikimic Acid and (6R)-6-Hydroxyshikimic Acid
《Chemical Research in Chinese Universities》2002年第2期146-152,共7页Chuanjun Song Shende Jiang Gurdial Singh 
(6S)-6-Fluoroshikimic acid 2 and (6 R ) 6 hydroxyshikimic acid 3 have been synthesized via an OsO 4 catalysed dihydroxylation of diene 7, which was derived from (-) shikimic acid 1.
关键词:Shikimate pathway Shikimic acid Fluoroshikimic acid DIHYDROXYLATION FLUORINATION 
First Asymmetry Synthesis and Stereochemistry of Glutinone
《Chinese Chemical Letters》2001年第10期881-882,共2页Zhe ZHANG Zhao Ming XIONG Yu Kun GUAN Guo Jun ZHENG Yu Lin LI 
We are grateful for financial support from the National Natural Science Foundation of China (Grant No. 29732060)
The first asymmetry synthesis of glutinone and its three diastereoisomers were carried out in 8 steps and the stereochemistry of this natural product was given out.
关键词:asymmetry synthesis asymmetry dihydroxylation SESQUITERPENOID 
Asymmetric Synthesis of (3R,5R)-3-((tert-Butyldimethylsily)oxy)-5-((Z)-2-Bromovinyl)-Tetrahydro-Furan-2-one,an Intermediate for the Synthesis of Fostriecin
《Chinese Chemical Letters》2000年第11期957-960,共4页Su Yun LIU Dao Fei HUANG Hai Hong HUANG Liang HUANG 
(3R,5R)-3-((tert-Butyldimethylsily)oxy)-5-((Z)-2-bromovinyl)-tetrahydro-furan-2-one, an intermediate for the synthesis of Fostriecin was achieved by intramolecular asymmetric induction in propene addition of (-)-8-phe...
关键词:Fostriecin DIHYDROXYLATION (-)-8-phenylmenthol asymmetric synthes 
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