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DNA_DAMAGE: 作品数：397被引量：1149H指数：14; 导出分析报告; 相关作者：黄百渠张瑜刘松陆军孙晋渊更多>>; 相关机构：东北师范大学首都师范大学上海交通大学医学院附属新华医院浙江林学院更多>>; 相关期刊：更多>>; 相关基金：国家自然科学基金国家重点基础研究发展计划国家教育部博士点基金中国博士后科学基金更多>>

Hexabromocyclododecane-induced Genotoxicity in Cultured Human Breast Cells through DNA Damage被引量：2: 《Biomedical and Environmental Sciences》2017年第4期296-300,共5页LI Rui Jing GAO Hui NA Guang Shui LU Zi Hao YAO Yao YANG Fan; supported by the National Natural Science Foundation of China(No.41406088);The open fund of Key Laboratory for Ecological Environment in Coastal Areas,State Oceanic Administration(201506); To investigate the genotoxicity and reveal the potential toxicological mechanisms of Hexabromocyclododecane （HBCD）, human breast cells HBL-100 were exposed to a sequence of HBCD concentrations （0, 5, 10, and 50 mg/...; 关键词：DNA HBCD Hexabromocyclododecane-induced Genotoxicity in Cultured Human Breast Cells through DNA Damage

Effect of Low Level Subchronic Microwave Radiation on Rat Brain被引量：5: 《Biomedical and Environmental Sciences》2016年第12期858-867,共10页Pravin Suryakantrao Deshmukh Kanu Megha Namita Nasare Basu Dev Banerjee Rafat Sultana Ahmed Mahesh Pandurang Abegaonkar Ashok Kumar Tripathi Pramod Kumari Mediratta; Indian Council of Medical Research (ICMR),New Delhi for grant in the form of the extramural research project vide sanction letter No.5/8/4-4(env) 07-NCD-I dated 3-08-09;One of the authors Pravin Suryakantrao Deshmukh is grateful to ICMR for Senior Research Fellowship (SRF) support; Objective The present study was designed to investigate the effects of subchronic low level microwave radiation （MWR） on cognitive function, heat shock protein 70 （HSP70） level and DNA damage in brain of Fischer r...; 关键词：BRAIN Cognitive function Comet assay DNA damage HSP70 Microwave radiation

p21 is Responsible for Ionizing Radiation-induced Bypass of Mitosis被引量：1: 《Biomedical and Environmental Sciences》2016年第7期484-493,共10页ZHANG Xu Rui LIU Yong Ai SUN Fang LI He LEI Su Wen WANG Ju Fang; supported by the National Natural Science Foundation of China[No.U1232125,31270895];the International Science&Technology Cooperation Program of China[No.2015DFR30940]; Objective To explore the role of p21 in ionizing radiation-induced changes in protein levels during the G2/M transition and long-term G2 arrest.Methods Protein expression levels were assessed by western blot in the hu...; 关键词：G2/M transition DNA damage Ionizing radiation G2 arrest

Single and Combined Effects of Estrone and 17 β-Estradiol on Male Goldfish: 《Biomedical and Environmental Sciences》2013年第3期176-184,共9页YAN Zhen Hua LU Guang Hua YANG Xiao Fan; supported by the National Natural Science Foundation of China (51079049);Qing Lan Project of Jiangsu Province; Objective To assess the single and combined effects of estrone （El） and 1713-estradiol （E2） on goldfish （ Carassius auratus）. Methods Batch tests were conducted. Serum levels of vitellogenin （VTG） and E2, gona...; 关键词：VITELLOGENIN DNA damage EROD activity Carassius auratus

Oxidative Stress, Biochemical and Histopathological Alterations in the Liver and Kidney of Female Rats Exposed to Low Doses of Deltamethrin (DM):A Molecular Assessment被引量：2: 《Biomedical and Environmental Sciences》2012年第6期672-683,共12页CHARGUI Issam GRISSA Intissar BENSASSI Fatma HRIRA Mohamed Yahia HAOUEM Samir HAOUAS Zohra BENCHEIKH Hassen; supported by the funds allocated to the Research Unit of Histology & Genetic 02/UR/08-03;the Tunisian Ministry of the Higher Education; Objective To evaluate histopathological alterations of the liver and kidney of female rats exposed to low doses of DM and its potential genotoxic activity. Methods Female Wistar rats were randomly assigned to control ...; 关键词：DELTAMETHRIN Rats LIVER KIDNEY HISTOPATHOLOGY Comet assay DNA damage.

Effects of Benzo(a)pyrene on the Contractile Function of the Thoracic Aorta of Sprague-dawley Rats被引量：1: 《Biomedical and Environmental Sciences》2012年第5期549-556,共8页GAN Tie Er XIAO Su Ping JIANG Ying HU Hu WU Yi Hua DUERKSEN-HUGHES Penelope J SHENG Jian Zhong YANG Jun; supported by National Natural Science Foundation of China,grant numbers30872140and81172692;Zhejiang Provincial Natural Science Foundation,R2100555;Ministry of Science and Technology,China,2009DFB30390; Abstract Objective To evaluate the possible vascular effects of an environment carcinogen benzo（a）pyrene （BaP）. Methods The cytotoxicit of BaP and rat liver S9 （0.25 mg/mL）-activated BaP were examined by MTT ass...; 关键词：DNA damage Benzo（a）pyrene Cardiovascular toxicity Vascular contraction

Formation of DNA Strand Breaks in Peripheral Lymphocytes of Rats After Exposure to Natural Sunlight: 《Biomedical and Environmental Sciences》2012年第2期245-249,共5页Dorival Mendes RODRIGUES-JUNIOR Ana Amélia de CARVALHO MELO Benedito Borges da SILVA Pedro Vitor LOPES-COSTA; Objective This paper aims to evaluate the genotoxicity in peripheral blood lymphocytes of rats after exposure to sunlight at different time points of day in a tropical region of Brazil（5oS,42oW）.Materials and Method...; 关键词：Comet assay DNA damage RATS SUNLIGHT Ultraviolet radiation

Evaluation of Oxidative Stress in Colorectal Cancer Patients被引量：14: 《Biomedical and Environmental Sciences》2008年第4期286-289,共4页DONG CHANG FAN WANG YA-SHUANG ZHAO HONG-ZHI PAN; the grant from the Health Bureau of Heilongjiang Province (No. 2005-126);the Natural Science Foundation of Heilongjiang Province (No. D2007-29); Objective To evaluate the oxidative stress in patients with colorectal cancer and to investigate the relationship between oxidative stress and colorectal cancer. Methods Seventy-six subjects were divided into two grou...; 关键词：Colorectal cancer Oxidative stress DNA damage Lipid peroxidation Protein oxidation

Isolation and Characterization of Radiation-resistant Lung Cancer D6-R Cell Line被引量：1: 《Biomedical and Environmental Sciences》2008年第4期339-344,共6页QI-CHUN WEI LI SHEN SHU ZHENG YONG-LIANG ZHU; Zhejiang Education Bureau (No. 20040207);the National Natural Science Foundation of China (No. 30470501); Objective To isolate an isogenic radioresistant cancer cell line after fractioned X-ray radiation and characterize the resistant cells. Methods D6 cells were exposed to repeated X-ray irradiation, and after a total do...; 关键词：RADIOSENSITIVITY CHEMOSENSITIVITY Cell cycle Apoptosis DNA damage DNA repair

Effects of Cadmium on Hepatocellular DNA Damage,Proto-Oncogene Expression and Apoptosis in Rats被引量：6: 《Biomedical and Environmental Sciences》2007年第2期146-153,共8页RI-AN YU LING-FEI HE XUE-MIN CHEN; This work was supported by the National Natural Science Foundation of China (No. 30271110).; Objective To study the effects of cadmium on hepatocellular DNA damage, expression of proto-oncogenes c-myc, c-fos, and c-jun as well as apoptosis in rats. Methods Cadmium chloride at the doses of 5, 10, and 20 μmol/...; 关键词：CADMIUM DNA damage PROTO-ONCOGENE APOPTOSIS

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