EPSTEIN-BARR_VIRUS

作品数:211被引量:791H指数:14
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The role of capecitabine as maintenance therapy in de novo metastatic nasopharyngeal carcinoma:A propensity score matching study被引量:5
《Cancer Communications》2020年第1期32-42,共11页Xue-Song Sun Sai-Lan Liu Yu-Jing Liang Qiu-Yan Chen Xiao-Yun Li Lin-Quan Tang Hai-Qiang Mai 
National Key R&D Program of China,Grant/Award Numbers:2016YFC0902003,2017YFC1309003,2017YFC0908500;National Natural Science Foundation of China,Grant/Award Numbers:81425018,81672868,81602371;Sun Yat-sen University Clinical Research 5010 Program,Grant/Award Numbers:201707020039,2014A020212103,16zxyc02;Sci-Tech Project Foundation of Guangzhou City,Grant/Award Number:201707020039;National Key Basic Research Program of China,Grant/Award Number:2013CB910304;Special Support Plan of Guangdong Province,Grant/Award Number:2014TX01R145;Sci-Tech Project Foundation of Guangdong Province,Grant/Award Number:2014A020212103;Health&Medical Collaborative Innovation Project of Guangzhou City,Grant/Award Number:201400000001;National Science&Technology Pillar Program during the Twelfth Five-year Plan Period,Grant/Award Number:2014BAI09B10;PhD Start-up Fund of Natural Science Foundation of Guangdong Province,China,Grant/Award Number:2016A030310221;cultivation foundation for the junior teachers in Sun Yat-sen University,Grant/Award Number:16ykpy28;foundation for major projects and new cross subjects in Sun Yat-sen University,Grant/Award Number:16ykjc38。
Background:Capecitabine was previously used as a second-line or salvage therapy for metastatic nasopharyngeal carcinoma(NPC)and has shown satisfactory curative effect as maintenance therapy in other metastatic cancers...
关键词:CAPECITABINE de novo Epstein-Barr virus LOCOREGIONAL maintenance therapy nasopharyngeal carcinoma propensity score matching RADIOTHERAPY survival 
The diagnostic and prognostic values of plasma Epstein-Barr virus DNA for residual cervical lymphadenopathy in nasopharyngeal carcinoma patients:a retrospective study被引量:4
《Cancer Communications》2019年第1期135-147,共13页Sai-Lan Liu Xue-Song Sun Xiao-Yun Li Lin-Quan Tang Qiu-Yan Chen Huan-Xin Lin Yu-Jing Liang Jin-Jie Yan Chao Lin Shan-Shan Guo Li-Ting Liu Yang Li Hao-Jun Xie Qing-Nan Tang Hu Liang Ling Guo Hai-Qiang Mai 
This study was supported by grants from the National Key R&D Program of China(2016YFC0902003,2017YFC1309003,2017YFC0908500);the National Natural Science Foundation of China(No.81425018,No.81672868,No.81602371,No.81572848,No.81772877,No.81372814,No.81773103);the Sun Yat-sen University Clinical Research 5010 Program,the Sci-Tech Project Foundation of Guangzhou City(201707020039);the National Key Basic Research Program of China(No.2013CB910304);the Special Support Plan of Guangdong Province(No.2014TX01R145);the Sci-Tech Project Foundation of Guangdong Province(No.2014A020212103,No.2012B031800255,No.2014A020212528);Guangzhou Science and Technology Planning Project China(No.2014J4100181);the Health&Medical Collaborative Innovation Project of Guangzhou City(No.201400000001);the National Science&Technology Pillar Program during the Twelfth Five-year Plan Period(No.2014BAI09B10);the PhD Start-up Fund of Natural Science Foundation of Guangdong Province,China(2016A030310221);the Cultivation Foundation for Junior Teachers of Sun Yat-sen University(16ykpy28);the Fundamental Research Funds for the Central Universities
Background:Currently,the diagnosis and treatment of nasopharyngeal carcinoma(NPC)patients with residual cervical lymphadenopathy following radical radiotherapy with or without chemotherapy are challenging.We investiga...
关键词:Nasopharyngeal carcinoma Residual cervical lymphadenopathy PROGNOSIS Epstein-Barr virus Fine needle aspiration cytology SURVIVAL 
Manipulation of the host cell membrane by humanγ-herpesviruses EBV and KSHV for pathogenesis被引量:2
《Virologica Sinica》2016年第5期395-405,共11页Fang Wei Qing Zhu Ling Ding Qing Liang Qiliang Cai 
supported by the National Natural Science Foundation of China(81471930,81402542);the National Basic Research Program of China(973 Program)(2012CB519001);the National Key Research and Development Program of China(2016YFC1200400)
The cell membrane regulates many physiological processes including cellular communication,homing and metabolism. It is therefore not surprising that the composition of the host cell membrane is manipulated by intracel...
关键词:cell membrane remodeling Epstein-Barr virus(EBV) Kaposi’s sarcoma-associated herpesvirus(KSHV) 
Co-infection of Epstein-Barr virus and human papillomavirus in human tumorigenesis被引量:3
《Chinese Journal of Cancer》2016年第3期100-108,共9页Ying Shi Song‑Ling Peng Li‑Fang Yang Xue Chen Yong‑Guang Tao Ya Cao 
supported by the National Basic Research Program of China[2011CB504300(Y.T.;Y.C.),2015CB553903(Y.T.)];the National High Technology Research and Development Program of China(863 Program)[2012AA02A501(Y.C.)];the National Natural Science Foundation of China[81,171,881 and81372427(Y.T.),81271763(S.L.),81,302,354(Y.S.)];the Hunan Natural Science Foundation of China[12JJ1013(Y.T.)]
Viral infections contribute to approximately 12%of cancers worldwide,with the vast majority occurring in developing countries and areas.Two DNA viruses,Epstein-Barr virus(EBV) and human papillomavirus(HPV),are associa...
关键词:EPSTEIN-BARR virus  Human papillomavirus  Co-infection  NASOPHARYNGEAL carcinoma  Cervical cancer Breast cancer  Prostate CANCER 
Comprehensive profiling of EBV gene expression in nasopharyn- geal carcinoma through paired-end transcriptome sequencing被引量:4
《Frontiers of Medicine》2016年第1期61-75,共15页Lijuan Hu Zhirui Lin YanhengWu Juqin Dong Bo Zhao Yanbing Cheng Peiyu Huang Lihua Xu Tianliang Xia Dan Xiong Hongbo Wang Manzhi Li Ling Guo Elliott Kieff YixinZeng 
This study was supported by 973 Program and 863 Program from the Ministry of Science and Technology of China (Nos. 2011CB504300 and 2015AA020931), National Natural Science Foundation of China (Nos. 91440106, 91019015, and 81302037), Ph.D. Startup of Guangzhou Medical University (No. 2012C65), Guangzhou Science and Technology Planing Project (No. 2014J4100181), and Young Teacher Training Program ofStm Yat-sen University (No. 13ykpy50).
The latent expression pattern of Epstein-Barr Virus (EBV)igenes in nasopharyngeal carcinoma (NPC) has been extensively investigated, and the expression of several lytic genes in NPC has been reported. However, com...
关键词:Epstein-Barr virus paired-end transcriptome sequencing latency genes lytic genes nasopharyngeal carcinoma 
Epigenetic dysregulation in Epstein-Barr virus-associated gastric carcinoma: Disease and treatments被引量:12
《World Journal of Gastroenterology》2014年第21期6448-6456,共9页Tung On Yau Ceen-Ming Tang Jun Yu 
Supported by Research Grants of National Basic Research Program of China (973 Program, 2010CB529305);Innovation and Technology Support Programme, Hong Kong (ITS/214/12)
Epstein-Barr virus(EBV)-associated gastric carcinoma(EBVaGC)comprises nearly 10%of gastric carcinoma cases worldwide.Recently,it was recognised to have unique clinicopathologic characteristics,including male predomina...
关键词:Epstein-Barr virus Gastric carcinoma Epigenetic dysregulation Aberrant DNA methylation Epigenetic therapies 
Epstein-Barr virus negative primary hepatic leiomyoma: Case report and literature review被引量:2
《World Journal of Gastroenterology》2013年第25期4094-4098,共5页Xian-Zhang Luo Chang-Sheng Ming Xiao-Ping Chen Nian-Qiao Gong 
Supported by Grants from the National Natural Science Foundation of China,No.81072441,to Gong NG;grants from the National High-Tech Research and Development Program(Program 863)of the Ministry of Science and Technology of China,2012AA021010,to Ming CS
Primary hepatic leiomyoma is a neoplasm of mesen-chymal origin and occurs only rarely. Secondary to benign smooth muscle proliferation, it is usually found in adult women and is associated with Epstein-Barr virus (EBV...
关键词:EPSTEIN-BARR virus PRIMARY HEPATIC LEIOMYOMA Cancer diagnosis Tumor resection DEVELOPMENTAL biology 
The Induction of Epstein-Barr Virus Early Antigen Expression in Raji Cells by GSM Mobile Phone Radiation
《Biomedical and Environmental Sciences》2013年第1期76-78,共3页LIU Yang WANG Ming Lian ZHONG Ru Gang MA Xue Mei WANG Qun ZENG Yi 
funded by the grants from Beijing Municipal Education Commission Science and Technology Project(KZ201110005003);National Key Basic Research Project(2011CB503702)
obile phones are widely used nowadays and there have been many reports suspecting mobile phone radiation-induced cancer during the past few years. But the results to date have given no consistent or convincing evidenc...
关键词:Mobile phone radiation EBV EA TPA IMMUNOCYTOCHEMISTRY 
Expression and Purification of the DNA Binding Domain of the Epstein-Barr Virus Nuclear Antigen 1
《生物技术通报》2008年第S1期405-410,共6页Meiru Hu~1 Ru Wei~(1,2)Lu Qian~1 Ming Yu~1 Ming Shi~1 Kun He~3 Jie Wang~3 Beifen Shen~1 Ning Guo~1 (1 Institute of Basic Medical Sciences,Beijing 100850 2 North China Coal Medical College 3 National Center of Biomedical Analysis,Beijing 100071) 
supposed by National Basic Research Program of China(973 Program)(2006CB504305);Beijing Natural Science Foundation(No.7051006).
To overexpress EBNA-1 in E.coli and generate the specific antibody,in this study,the antigenicity,epitope and hydrolysis of EBNA-1 were analyzed using the computer design software Biosun.Based on the prediction by com...
关键词:EBNA-1 EXPRESSION PURIFICATION E.COLI 
Role of Epstein-Barr Virus Encoded Latent Membrane Protein 1 in the Carcinogenesis of Nasopharyngeal Carcinoma被引量:34
《Cellular & Molecular Immunology》2007年第3期185-196,共12页Hui Zheng Lili Li Duosha Hu Xiyun Deng Ya Cao 
grants from State Key Basic Research and Development Plan (973) of the Ministry of Science and Technology of China (2004CB518703); National High Technology Research and Development Program (863) of China (N0.2006AA02Z481); National Science Fund for Distinguished Young Scholars 0verseas (30428008); Hong Kong Cooperation Fund Project of National Natural Science Foundation of China (30418004).
Epstein-Barr virus (EBV)-encoded latent membrane protein 1 (LMPI) has been known to have oncogenic properties during latent infection in nasopharyngeal carcinoma (NPC). Our studies focused on the role of LMP1 in...
关键词:latent membrane protein 1 nasopharyngeal carcinoma signal transduction 
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