ESSENTIAL

作品数:798被引量:1986H指数:20
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相关领域:医药卫生更多>>
相关作者:陈汐敏丁贵鹏接雅俐唐震邹建刚更多>>
相关机构:中国科学院复旦大学北京大学南京大学更多>>
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相关基金:国家自然科学基金国家重点基础研究发展计划中国博士后科学基金国家社会科学基金更多>>
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Life’s Essential 8 and risk of non-communicable chronic diseases:Outcome-wide analyses
《Chinese Medical Journal》2024年第13期1553-1562,共10页Yuetian Yu Ying Sun Yuefeng Yu Yuying Wang Chi Chen Xiao Tan Yingli Lu Ningjian Wang 
Science and Technology Commission of Shanghai Municipality(No.19140902400);Shanghai Municipal Health Commission(No.2022XD017);Clinical Research Plan of SHDC(No.SHDC2020CR4006);Shanghai Municipal Human Resources and Social Security Bureau(No.2020074)
Background:Life’s Simple 7,the former construct of cardiovascular health(CVH)has been used to evaluate adverse non-communicable chronic diseases(NCDs).However,some flaws have been recognized in recent years and Life...
关键词:Life’s Essential 8 Cardiovascular risk score Non-communicable chronic disease Population health management Cohort analysis Healthy lifestyle UK Biobank 
Zinc finger and BTB domain-containing protein 46 is essential for survival and proliferation of acute myeloid leukemia cell line but dispensable for normal hematopoiesis被引量:1
《Chinese Medical Journal》2020年第14期1688-1695,共8页Yuan-Yuan Liu Fei-Fei Xiao Bi-Jie Yang Xi Li Shuang-Nian Xu Zhi-Wei Chen Ping Li Yong-Xiu Huang Xue-Mei Fu Xing-Qin Huang Guang-Ling Zheng Jie-Ping Chen Yu Hou 
This study was supported by grants from the National Key R&D Program of China(No.2017YFA0106700);Army Major Scientific Research Projects(No.AWS17J007);National Natural Science Foundation of China(No.81670096 and No.81700185);Military Medical Innovation Program(No.SWH2018LJ-07 and No.SWH2018QNKJ-17);and Basic Research Program on Civil-military Integration(No.SWH2017YBXM-06).
Background:Zinc finger and BTB domain-containing protein 46(Zbtb46)is a transcription factor identified in classical dendritic cells,and maintains dendritic cell quiescence in a steady state.Zbtb46 has been reported t...
关键词:Zbtb46 transcription factor AML Hematopoietic stem cells 
Acute myocardial infarction and sub-acute stent thrombosis associated with occult essential thrombocythemia被引量:2
《Chinese Medical Journal》2014年第19期3512-3513,共2页Zafer Isilak Mehmet Tezcan Murat Atalay Ejder Kardesoglu 
70-year-old female with no Aprevious cardiac history resented with complaints of severe chest and back pain lasting for 20 minutes. She had a past history of type 2 diabetes mellitus for five years and hypertension fo...
关键词:acute myocardial infarction essential thromboeythemia sub-acute stent thrombosis 
Differences and determinants in access to essential public health services in China: a case study with hypertension people and under-sixes as target population被引量:2
《Chinese Medical Journal》2014年第9期1626-1632,共7页Niu Hongli Tian Miaomiao Ma Anning Wang Chunping Zhang Liang 
Background Since 2009, health reform had launched in China and essential public health services were provided for all residents to ensure service equity and accessibility, and to achieve sustained population-wide heal...
关键词:public health individual difference epidemiologic determinants 
Retinol dehydrogenase, RDHll, is essential for the heart development and cardiac performance in zebrafish
《Chinese Medical Journal》2013年第4期722-728,共7页WANG Wei ZHANG Li-feng GUI Yong-hao SONG Hou-yan 
This work was supported by the grants from the National Natural Science Foundation of China (No. 30972959) and Doctoral Fund of Ministry of Education of China (new teacher) (No. 200802461110).
Background Retinoic acid (RA) is a potent signaling molecule that plays pleiotropic roles in patterning, morphogenesis, and organogenesis during embryonic development. The synthesis from retinol (vitamin A) to ret...
关键词:RDHll neural crest cells MORPHOLINO cardiac performance ZEBRAFISH 
Imbalance of endogenous homocysteine and hydrogen sulfide metabolic pathway in essential hypertensive children被引量:23
《Chinese Medical Journal》2007年第5期389-393,共5页CHEN Li INGRID Sumou DING Ya-guang LIU Ying QI Jian-guang TANG Chao-shu DU Jun-bao 
the Key Science andTechnology Program of Beijing (No. H030930030530 and No. H030930030031);National Natural Science Foundation of China (No. 30425010 and No. 30630031);Major Basic Research Project of China (No. 2006CB503807).
Background Hypertension is a common disease of the cardiovascular system. So far, the pathogenesis of primary hypertension remains unclear. The elaboration of its pathogenesis is an important topic in the field which ...
关键词:HOMOCYSTEINE hydrogen sulfide HYPERTENSION systolic blood pressure 
Association of angiotensin Ⅱ type 1 receptor gene polymorphism with essential hypertension被引量:3
《Chinese Medical Journal》2001年第12期17-19,101-102,共5页蒋珍妮 赵文胜 俞锋 徐耕 
Objective To determine whether the polymorphism A1166C in the angiotensin Ⅱ type 1 receptor (AT1R) gene is associated with essential hypertension Methods A casecontrol study was carried out using 125 hypertensive and...
关键词:essential  hypertension  ·  angiotensin   ·  receptor    ·   gene  polymorphism 
Inherited disturbances of phenylalanine metabolic kinetics in essential hypert ension
《Chinese Medical Journal》2001年第8期16-19,102,共5页赵光胜 顾天华 李振波 
ThisstudywassupportedbythegrantoftheNationalNaturalSciencesFoundationofChina (No 391735 0 ;No 39470 62 6)
Objective To clarify whether the disturbances in metabolic kinetics of the essential aminoacid, phenylalanine (phe), are implicated in the genetic pathogenesis of essential hypertension (EH).Methods 1. L-(2, 3D3)-le...
关键词:essential hypertension  ·   phenylalanine  ·   spontaneously hypertensive rat  (SHR)  ·   metabolic kinetics  ·   stable isotope tracer method  ·     inherited pathogenesis 
Gene polymorphisms of the renin-angiotensin system in essential hypertension被引量:3
《Chinese Medical Journal》1999年第2期20-25,共6页刘英 邱长春 周文郁 郑勇 候淑芹 曹军 
Objective To determine whether angiotensin converting enzyme (ACE) gene, angiotensinogen (AGT) gene and angiotensin Ⅱ receptor 1 (AT1R) gene are implicated in Chinese essential hypertension (EH). Methods The case ...
关键词:RENIN angiotensin SYSTEM · GENE polymorphism · ESSENTIAL HYPERTENSION · genetics · Chinese population 
Holistic approach to health education on AIDS
《Chinese Medical Journal》1999年第2期74-80,共7页Ning Wei, Bing Zhang, Tao Li, Abdul Fattah, Miyuki Yamamoto and Nobuhiro Maruchi 
Objective To identify a method for health education using the example of an educational seminar on AIDS prevention and control at Hebei Medical University in China, 1994.Methods Our goal is the theoretical formulati...
关键词:community care community control cultural norm essential quality holistic approach human ecosystems 
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