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作品数：1212被引量：1729H指数：15
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相关作者：何孔旺倪艳秀杨柏云孙小琴何维更多>>
相关机构：北京大学复旦大学江苏省农业科学院西南大学更多>>
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Establishment and characterization of a new human gallbladder cancer cell line,OCUG-2
《World Journal of Experimental Medicine》2025年第2期130-141,共12页Qiang Wang Canfeng Fan Gen Tsujio Takashi Sakuma Koji Maruo Yurie Yamamoto Daiki Imanishi Kyoka Kawabata Hinano Nishikubo Saki Kanei Rika Aoyama Syuhei Kushiyama Masaichi Ohira Masakazu Yashiro 
BACKGROUND Gallbladder cancer(GBC)is a highly aggressive malignant tumor originating from the biliary tract.As one of the most common malignancies in the biliary system,GBC is particularly challenging due to its tende...
关键词：Gallbladder cancer Cell line Insulin-like growth factor 1 receptor Molecular target Mouse model 
Establishment and characterization of liver-specific Apoa4-C re and Cyp2c11-Cre rat models in juvenile and adult stages
《Animal Models and Experimental Medicine》2025年第4期718-727,共10页Wei Dong Xiang Gao Feifei Guan Jirong Pan Wei Chen Li Zhang Lianfeng Zhang 
CAMS Innovation Fund for Medical Sciences(CIFMS),Grant/Award Number:2021-I2M-1-035;National Natural Science Foundation of China,Grant/Award Number:31970508。
Background:Liver diseases are a major contributor to both morbidity and mortality.Conditional knockout animals are always produced through crossing floxed animals with a tissue-specific Cre animal.The use of floxed ra...
关键词：Apoa4 CRE Cyp2c11 LIVER RAT 
Establishment of somatic embryogenesis regeneration system and transcriptome analysis of early somatic embryogenesis in litchi
《Horticultural Plant Journal》2025年第2期535-547,共13页Yaqi Qin Bo Zhang Shiqian Wang Wuyan Guo Zhike Zhang Yonghua Qin Jietang Zhao Guibing Hu 
supported by the National Natural Science Fund of China(Grant Nos.31872066 and 32272663);the Science and Technology Planning Project of Guangzhou(Grant No.2023B01J2002);the Key Research and Development Program of Hainan(Grant No.ZDYF2023XDNY052);the Seed Industry Engineering Project of Ministry of Agriculture and Rural Affairs of Guangdong(Grant Nos.2022-NPY-00-004 and 2022-NBH-00-001)。
Litchi chinensis Sonn.is an important economic fruit tree in tropical and subtropical regions.Regrettably,the efficiency of plant regeneration via somatic embryogenesis in litchi is typically low due to the poor conve...
关键词：Litchi chinensis Somatic embryogenesis TRANSCRIPTOME LcBBM2 
Establishment and validation of a nomogram for predicting esophagogastric variceal bleeding in patients with liver cirrhosis
《World Journal of Gastroenterology》2025年第9期54-67,共14页Lun-Xi Liang Xiao Liang Ya Zeng Fen Wang Xue-Ke Yu 
Supported by the National Natural Science Foundation of China,No.82270594;the National Natural Science Foundation for Youths of China,No.82103151;the Fundamental Research Funds for the Central Universities of Central South University,No.2022ZZTS0265;the Graduate Research Innovation Project of Hunan Province,No.CX20220347.
BACKGROUND Patients with decompensated liver cirrhosis suffering from esophagogastric variceal bleeding(EGVB)face high mortality.AIM To investigate the risk factors for EGVB in patients with liver cirrhosis and establ...
关键词：Liver cirrhosis Esophagogastric variceal bleeding Diagnostic model NOMOGRAM Retrospective study 
Establishment of the multi-organ circulatory and supervision system(MOCS)
《Science Bulletin》2025年第4期488-491,共4页Lina Kang Jingyi Sheng Xue Bao Guozhen He Liang Mao Qiang Wang Jianrong Lu Min Zhou Yepeng Zhang Ling He Yuqin Guo Xiang Guan Zhipeng Wu Xuguang Jin Biao Xu Ning Gu 
supported by the Major Scientific and Technological Infrastructure Cultivation Projects of Jiangsu Province,China,the National Natural Science Foundation of China(61821002);the Natural Science Foundation of Jiangsu Province(BK20222002);Jiangsu Provincial Medical Key Discipline(ZDXK202208).
Human body exemplifies one of the most intricate and sophisticated systems,characterized by nonlinear interactions of numerous components[1].Advances in science and technology have greatly enhanced our understanding o...
关键词：SYSTEM COORDINATED ORGANS 
Evaluation of the shear stability of aerobic granular sludge from a pilot-scale membrane bioreactor:Establishment of a quantitative method
《Journal of Environmental Sciences》2025年第2期579-590,共12页Biao Yang Bingduo Wang Liying Bin Weirui Chen Xinyi Chen Ping Li Shanglong Wen Shaosong Huang Zhiqi Zhang Bing Tang 
supported by the Key Technologies Research and Development Program of Guangzhou (No.2023B03J1284);Guangdong Yuehai Water Investment Co.,Ltd. (No.CC80-QT01-2020-0010).
This work established a quantitative method to access the shear stability of aerobic granular sludge(AGS)and validated its feasibility by using the mature AGS from a pilot-scale(50 tons/day)membrane bioreactor(MBR)for...
关键词：Shear stability Quantitative evaluation Aerobic granular sludge Membrane bioreactor Pilot-scale study Municipal wastewater 
Establishment of goat mammary organoid cultures modeling the mammary gland development and lactation
《Journal of Animal Science and Biotechnology》2025年第1期193-205,共13页Lei Jia Wenying Zhang Tao Luo Yongtao Li Jianhong Shu Julie Strand Yuan Yue Stig Purup Jianxin Liu Hengbo Shi 
Innovation 2030-Biological Breeding-Major Projects(2022ZD04014);Key R&D Program of Zhejiang Province(2022C04017).
Background Although several cell culture systems have been developed to investigate the function of the mam-mary gland in dairy livestock,they have potential limitations,such as the loss of alveolar structure or genet...
关键词：Cell-based milk production LACTATION Mammary gland Organoid 
Establishment and verification of theoretical model for underwater light-sheet Scheimpflug LiDAR system
《Science China(Technological Sciences)》2025年第1期50-57,共8页Fei FENG Guojun WU Bo LIU Xu ZHAO Yafeng WU Jinghan XU 
supported by the Special Project of Strategic Leading Science and Technology of Chinese Academy of Sciences(Grant No.XDA22030201)。
The Scheimpflug imaging in the air can increase the depth-of-view and has been well studied with an accurate Scheimpflug imaging model.However,there is no corresponding underwater light-sheet Scheimpflug(ULSS)imaging ...
关键词：underwater optical detection 3D detection range resolution Scheimpflug imaging LIDAR 
Establishment and Validation of Diagnostic and Prognostic Prediction Models for Liver Metastasis in Patients with Rectal Cancer:A SEER-based Study
《Proceedings of Anticancer Research》2024年第6期168-197,共30页Huimin Wang Ya Zheng Zhaofeng Chen 
Department of Science and Technology of Gansu Province,Major Project of Joint Scientific Research Fund of Gansu Province“Gastric Cancer Epidemiology,Pathogenesis and Diagnosis and Treatment Technology Research”(Project No.23JRRA1487);Lanzhou Science and Technology Bureau,the First Hospital of Lanzhou University Lanzhou R&D Platform Construction Project Lanzhou Science and Technology Program Digest“Screening and Verification of Early Screening Markers for Gastric Cancer and Precancerous Lesions”(Project No.2023-1-19);The Foundation of The First Hospital of Lanzhou University,Hospital Foundation of the First Hospital of Lanzhou University Digestion 2021“Study on the Mechanism of Exosome(LINC00957)Encoded Micropeptide Protein in Promoting the Occurrence and Development of Gastric Cancer”。
Background:Rectal cancer is one of the most common gastrointestinal tumors,among which the liver is the most common site of distant metastasis and liver metastasis that leads to poor prognosis.This study aimed to deve...
关键词：Rectal cancer Liver metastasis NOMOGRAM PREDICTOR Diagnosis Prognosis 
Establishment of immortalized rabbit bone marrow mesenchymal stem cells and a preliminary study of their osteogenic differentiation capability
《Animal Models and Experimental Medicine》2024年第6期824-834,共11页Yao Zhang Chang Xu Yun Huang Dongmei Tan Wenping Luo Yan Zhang Yi Tan 
Background:A stable and standardized source of mesenchymal stem cells is a prerequisite for bone repair tissue engineering research and application.We aimed to establish a stable cell line of bone marrow mesenchymal s...
关键词：bone marrow mesenchymal stem cells bone morphogenetic protein 9 GelMA hydrogel IMMORTALIZATION 
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