ETODOLAC

作品数：5被引量：4H指数：1
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Neuroprotective role of antioxidant and pyranocarboxylic acid derivative against AlCl_(3) induced Alzheimer’s disease in rats
《Journal of Coastal Life Medicine》2014年第7期571-578,共8页Sarabjeet Singh Ramandeep Singh Ajay SKushwah Gaurav Gupta 
Supported by ASBASJS Memorial College of Pharmacy Bela,Ropar(Punjab)(Grant No.ASBASJSCOP/PTU PROJ/AR/2010-2011/09).
Objective:To assess potential of quercetin and etodolac to treat oxidative stress in neuronal death and inflammation in Alzheimer’s disease of AlCl3 induced rat models.All results of this AlCl_(3)model are compared w...
关键词：QUERCETIN ETODOLAC Aluminum chloride Superoxide dismutase Reduced glutathione Thiobarbituric acid reactive substance 
Etodolac Attenuates Hippocampal Blood Flow Responses Induced by Tooth Pulp Stimulation in Rats
《Neuroscience & Medicine》2011年第3期295-298,共4页Makoto Hasegawa Junichi Hada Tetsuya Abe Nao Ohtsu Kousuke Honda Masahiro Urade 
In this study, we investigated whether increases in hippocampal blood flow (HBF) by tooth pulp stimulation (TPS) are mediated via the activation of cyclooxygenase-2 (COX-2). We measured mean arterial blood pressure (M...
关键词：CYCLOOXYGENASE-2 (COX-2) ETODOLAC FEAR Memory HIPPOCAMPAL BLOOD Flow Mean Arterial BLOOD Pressure Tooth Pulp STIMULATION 
Analysis of chiral non-steroidal anti-inflammatory drugs flurbiprofen,ketoprofen and etodolac binding with HSA被引量：4
《Journal of Pharmaceutical Analysis》2011年第3期184-190,共7页Chang-Chuan Guo Yi-Hong Tang Hai-Hong Hu Lu-Shan Yu Hui-Di Jiang Su Zeng 
supported by National Major Projects for Science and Technology Development of Ministry Science and Technology of China (2009ZX09304-003)
The protein binding of non-steroidal anti-inflammatory drugs flurbiprofen, ketoprofen and etodolac with human serum albumin （HSA） was investigated using indirect chiral high performance liquid chromatography （HPLC...
关键词：Protein binding Non-steroidalanti-inflammatorydrugs ENANTIOMER STEREOSELECTIVITY Human serum albumin 
Myriad转让肿瘤技术给Salmedix
《国外药讯》2005年第9期23-24,共2页陆义（摘） 
MyriadGenetics公司已经将其抗肿瘤药物技术的专有许可权转让给Salmedix公司。该技术使用了etodolac的R对映异构体，salmedix公司的化合物SDX-101即以此技术为基础。Etodolac是R和S异构体的混合物。SDX-101可诱导恶性淋巴细胞凋亡，正...
关键词：抗肿瘤药物 转让 慢性淋巴细胞性白血病 ETODOLAC ETODOLAC 淋巴细胞凋亡 对映异构体 技术使用 S异构体 
Pharmacokinetic difference between S-(+)- and R-(-)-etodolac in rats
《Acta Pharmacologica Sinica》2004年第8期996-999,共4页Jing-minSHI Shun-guoLAI Chang-jiangXU Geng-liDUAN DuanLI 
AIM: To study whether etodolac enantiomers have pharmacokinetic difference after oral administration. METHODS: Fourteen rats, divided into two groups randomly, were orally given S-(+)- or R-(-)-etodolac at a single do...
关键词：ETODOLAC non-steroidal anti-inflammatory agents PHARMACOKINETICS STEREOISOMERISM 
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