HIPPOCAMPAL

作品数：391被引量：1008H指数：12
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相关领域：医药卫生生物学更多>>
相关作者：庄雄杰罗竹人陈汝筑朱小南寿彩华更多>>
相关机构：重庆医科大学厦门大学福建医科大学浙江大学更多>>
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相关基金：国家自然科学基金国家重点基础研究发展计划中国博士后科学基金广东省自然科学基金更多>>
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Sox2-overexpressing neural stem cells alleviate ventricular enlargement and neurological dysfunction in posthemorrhagic hydrocephalus
《Neural Regeneration Research》2026年第2期769-779,共11页Baocheng Gao Haoxiang Wang Shuang Hu Kunhong Zhong Xiaoyin Liu Ziang Deng Yuanyou Li Aiping Tong Liangxue Zhou 
supported by the National Natural Science Foundation of China,Nos.82473334(to LZ),82401629(to XL);the Major Scientific and Technological Achievements Transformation Project of Ningxia Hui Autonomous Region,No.2022CJE09013(to LZ);Mianyang Science and Technology Bureau(Mianyang Science and Technology Program),No.2023ZYDF097(to LZ);NHC Key Laboratory of Nuclear Technology Medical Transformation(Mianyang Central Hospital),No.2023HYX001(to LZ);Spinal Cord Diseases Clinical Medical Center of Yunnan Province,No.2024JSKFKT-16(to BG);the Natural Science Foundation of Sichuan Province,No.2024NSFSC1646(to XL);the China Postdoctoral Science Foundation,Nos.GZC20231811(to XL),2024T170601(to XL)and 2024M76228(to XL).
Neural stem cells(NSCs)have the potential for self-renewal and multidirectional differentiation,and their transplantation has achieved good efficacy in a variety of diseases.However,only 1%-10%of transplanted NSCs sur...
关键词：ANGIOGENESIS cerebrospinal fluid hippocampal transplantation inflammation MICROGLIA neural stem cells NEUROGENESIS posthemorrhagic hydrocephalus retinoic acid ^(Sox2) 
Small molecule inhibitor DDQ-treated hippocampal neuronal cells show improved neurite outgrowth and synaptic branching
《Neural Regeneration Research》2025年第9期2624-2632,共9页Jangampalli Adi Pradeepkiran Priyanka Rawat Arubala P.Reddy Erika Orlov PHemachandra Reddy 
supported by NIH grants AG079264(to PHR)and AG071560(to APR)。
The process of neurite outgrowth and branching is a crucial aspect of neuronal development and regeneration.Axons and dendrites,sometimes referred to as neurites,are extensions of a neuron's cellular body that are use...
关键词：diethyl(3 4-dihydroxyphenethylamino)(quinolin-4-yl)methylphosphonate(DDQ) hippocampal neuronal cells HT22 neurite outgrowth neuronal development small molecule 
New aspects of a small GTPase RAB35 in brain development and function
《Neural Regeneration Research》2025年第7期1971-1980,共10页Ikuko Maejima Ken Sato 
supported by the Japan Society for the Promotion of Science KAKENHI(grant Nos.23K05678 to IM,19H05711 and 20H00466 to KS);the Joint Research Program of Institute for Molecular and Cellular Regulation,Gunma University(to KS)。
In eukaryotic cells,organelles in the secretory,lysosomal,and endocytic pathways actively exchange biological materials with each other through intracellular membrane trafficking,which is the process of transporting t...
关键词：ENDOCYTOSIS ENDOSOMES hippocampal development neurodegenerative diseases RAB35 
Neuropeptide cholecystokinin:a key neuromodulator for hippocampal functions
《Neural Regeneration Research》2025年第7期1991-1992,共2页Fengwen Huang Stephen Temitayo Bello 
Spatial memory is crucial for survival within external surroundings and wild environments.The hippocampus,a critical hub for spatial learning and memory formation,has received extensive investigations on how neuromodu...
关键词：abundant FUNCTIONS MODULATOR 
Effects of xiusanzhen acupuncture on hippocampal CA1 region damage and microglia activation in rats with vascular dementia:A trigeminal nerve perspective
《World Journal of Acupuncture-Moxibustion》2025年第1期75-83,共9页Jie LI Qiang WANG Yuan WANG Jun-yang LIU Jie GUO Hua LI Hao-bin ZHANG Jie LIU An-ren ZHANG Hai-fa QIAO 
Supported by The National Natural Science Foundation of China Young Scientists Fund:82004480。
Objective:This study aimed to observe the effects of xiusanzhen acupuncture(olfactory three-needling therapy)on the behavior,hippocampal histopathology and microglial(MG)activation of rats with vascular dementia(VD),a...
关键词：Trigeminal nerve Xiusanzhen acupuncture Vascular dementia MICROGLIA 
Ventral Hippocampal CA1 GADD45B Regulates Susceptibility to Social Stress by Influencing NMDA Receptor‑Mediated Synaptic Plasticity
《Neuroscience Bulletin》2025年第3期406-420,共15页Mengbing Huang Jian Bao Xiaoqing Tao Yifan Niu Kaiwei Li Ji Wang Xiaokang Gong Rong Yang Yuran Gui Hongyan Zhou Yiyuan Xia Youhua Yang Binlian Sun Wei Liu Xiji Shu 
supported by the National Natural Science Foundation of China(82201667,82371195,and 82304474);the Research Fund of Jianghan University(2023JCYJ15).
Growth arrest DNA damage-inducible protein 45β(GADD45B)has been reported to be a regulatory factor for active DNA demethylation and is implicated in the modulation of synaptic plasticity and chronic stress-related ps...
关键词：Chronic stress Ventral hippocampal CA1 GADD45B NMDA receptor Synaptic plasticity 
Multi-channel microelectrode arrays for detection of single-cell level neural information in the hippocampus CA1 under general anesthesia induced by low-dose isoflurane被引量：1
《Fundamental Research》2025年第1期72-81,共10页Ruilin Hu Penghui Fan Yiding Wang Jin Shan Luyi Jing Wei Xu Fan Mo Mixia Wang Yan Luo Ying Wang Xinxia Cai Jinping Luo 
sponsored by the National Natural Science Foundation of China(T2293731,61960206012,62121003,62171434,61971400,61975206,and 61973292);the Scientific Instrument Developing Project of the Chinese Academy of Sciences(GJJSTD20210004);the National Key Research and Development Program(2022YFC2402501,2022YFB3205602);Major Program of Scientific and Technical Innovation 2030(2021ZD0201603).
Timely monitoring of anesthesia status during surgery is important to prevent an overdose of isoflurane anesthesia.Therefore,in-depth studies of the neural mechanisms of anesthetics are warranted.Hippocampal CA1 plays...
关键词：Micro electrode array Hippocampal CA1 Isoflurane anesthesia SPIKE Local field potentials 
Tofacitinib prevents depressive-like behaviors through decreased hippocampal microgliosis and increased BDNF levels in both LPS-induced and CSDS-induced mice
《Acta Pharmacologica Sinica》2025年第2期353-365,共13页Ya-nan Gao Kai-jun Pan Yong-mei Zhang Ying-bei Qi Wen-gang Chen Ting Zhou Hai-chao Zong Hao-ran Guo Jin-wen Zhao Xing-chen Liu Zi-tong Cao Ze Chen Tao Yin Yi Zang Jia Li 
founded by National Natural Science Foundation of China grant 82001572;National Natural Science Foundation of China grant 81971265;National Science&Technology Major Project“Key New Drug Creation and Manufacturing Program”grant 2018ZX09711002-007-002;Shanghai Commission of Science and Technology grant 2021000003;Shanghai Science and Technology Development Funds(Shanghai Commission of Science and Technology)grant 19JC1416300.
Depressive disorders are a global mental health challenge that is closely linked to inflammation,especially in the post-COVID-19 era.The JAK-STAT pathway,which is primarily associated with inflammatory responses,is no...
关键词：tofacitinib depression JAK-STAT pathway MICROGLIOSIS synaptic defects 
Berberine Hydrochloride Improves Cognitive Function and Hippocampal Antioxidant Status in Subchronic and Chronic Lead Poisoning
《Chinese Journal of Integrative Medicine》2025年第1期49-54,共6页Fatemeh Zare Mehrjerdi Azadeh Shahrokhi Raeini Fatemeh Sadate Zebhi Zeynab Hafizi Reyhaneh Mirjalili Faezeh Afkhami Aghda 
Supported by the Research Project of Shahid Sadoughi University of Medical Sciences and Health Services(No.5894)Yazd Neuroendocrine Research Center;School of Medicine,Shahid Sadoughi University of Medical Sciences and Health Services,Yazd(8915133149),Iran。
Objective: To determine the neuroprotective effects of berberine hydrochloride(BBR) against lead-induced injuries on the hippocampus of rats. Methods: Wistar rats were exposed orally to doses of 100 and 500 ppm lead a...
关键词：lead acetate BERBERINE HIPPOCAMPUS oxidative stress Morris water maze 
Distinct cortical connectome organization of hippocampal subfields is associated with episodic memory
《Science Bulletin》2025年第1期33-37,共5页Debin Zeng Deyu Li Qiongling Li Yong He Shuyu Li 
supported by the Scientific and Technological Innovation 2030-Major Projects(2021ZD0200500);the National Natural Science Foundation of China(32271146 and 82021004);the Startup Funds for Top-notch Talents at Beijing Normal University。
The hippocampus is considerably important in terms of its phylogenetic origins and participates in an extensive array of cognitive tasks and behaviors[1].The hippocampus can be partitioned into subfields based on its ...
关键词：partitioned considerably FIELDS 
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