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Role of triggering receptor expressed on myeloid cells 1/2 in secondary injury after cerebral hemorrhage
《World Journal of Clinical Cases》2025年第9期1-12,共12页Fan Yi Hao Wu Hai-Kang Zhao 
Supported by Shanxi Provincial Key Research and Development Plan Project,No.2020ZDLSF01-02;Doctor Foundation of the Second Affiliated Hospital of Xi’an Medical University,No.X2Y-R11.
Intracerebral hemorrhage(ICH)is a common severe emergency in neurosurgery,causing tremendous economic pressure on families and society and devastating effects on patients both physically and psychologically,especially...
关键词：Cerebral hemorrhage Secondary injury Triggering receptor expressed on myeloid cells 1/2 NEUROSURGERY Inflammatory response 
EBF1 expressed in the dermal papilla regulates hair type and length
《Genes & Diseases》2025年第1期134-136,共3页Hongzhi Song Leslie Lei Zhang Wei-qi Zhong Eve Qian Chen Xi-Xi Qiu Zi-Ling Tang Xin-Hua Liao 
supported by the National Key Research and Development Program of China(No.2020YFA01130002);the National Natural Science Foundation of China(No.81972563).
Loss of excessive hair growth causes psychological distress in many people,seriously affecting their social confidence and quality of life.The dermal papilla(DP)plays a pivotal role in regulating hair follicle(HF)morp...
关键词：DISTRESS DERMAL HAIR 
Role of triggering receptor expressed on myeloid cells 2 in the pathogenesis of non-alcoholic fatty liver disease
《World Journal of Hepatology》2025年第2期31-46,共16页Li-Hui Zhang Su-Tong Liu Qing Zhao Xiao-Yan Liu Tong Liu Qiang Zhang Ming-Hao Liu Wen-Xia Zhao 
Supported by Henan Province's"Double First-Class"Creation of Scientific Research in Traditional Chinese Medicine,No.HSRPDFCTCM-2023-7-23 and No.STG-ZYX02-202117;National Traditional Chinese Medicine Clinical Research Base Scientific Research Special Project,No.2022JDZX098 and No.2022JDZX114;National Natural Science Foundation of China,No.82205086;The 9th China Association for Science and Technology Young Talent Support Project,No.2023QNRC001.
Non-alcoholic fatty liver disease(NAFLD)is a progressive disease.Without effective interventions,NAFLD can gradually develop to non-alcoholic steatohepatitis,fatty liver fibrosis,liver cirrhosis and even hepatocellula...
关键词：Triggering receptor expressed on myeloid cells 2 Non-alcoholic fatty liver disease MACROPHAGE Lipid metabolism Inflammation 
Mechanism of Action of the Traditional Chinese Medicine Formula Weichang’an in the Treatment of Gastric Cancer Based on TMT Proteomics Analysis
《Chinese Medicine and Natural Products》2024年第4期173-181,共9页Yaofei Niu Weixia Chen Yajie Ding Yan Xu Aiguang Zhao 
funded by the Special Research Project of Traditional Chinese Medicine in Henan Province(2022ZY2031).
Objective The aim of the study was to screen key proteins involved in the treatment of human gastric cancer subcutaneous xenografts in nude mice by the traditional Chinese medicine formula Weichang’an and to explore ...
关键词：TMT proteomics Weichang’an gastric cancer differentially expressed protein 
Allergenic risk assessment of porcine myoglobin expressed by engineered Komagataella Phaffii
《Fundamental Research》2024年第5期1339-1348,共10页Yongli Ye Jiadi Sun Jiayuan Xu Peipei Li Lina Sheng Yuan Qian Jian Ji Xiaomin Han Xinrui Zhao Jingwen Zhou Xiulan Sun 
supported by the National Natural Science Foundation of China(32125031);the National Key Research and Development Program of China(2021YFC2101400);the Fundamental Research Funds for the Central Universities(JUSRP222001);Collaborative Innovation Center of Food Safety and Quality Control in Jiangsu Province,Jiangnan University.
Myoglobin produced by fermentation using engineered Komagataella phaffii is an important color additive in meat analogue products,but its allergenicity is poorly understood.Here,we initially searched the Allergen Onli...
关键词：Porcine myoglobin Komagataella phaffii Allergenic risk assessment Immune response Purification process 
Triggering Receptor Expressed on Myeloid Cells 2 Alleviated Sevoflurane-Induced Developmental Neurotoxicity via Microglial Pruning of Dendritic Spines in the CA1 Region of the Hippocampus
《Neuroscience Bulletin》2024年第9期1215-1229,共15页Li Deng Shao-Yong Song Wei-Ming Zhao Xiao-Wen Meng Hong Liu Qing Zheng Ke Peng Fu-Hai Ji 
National Natural Science Foundation of China(82072130 and 82001126);Key Medical Research Projects in Jiangsu Province(ZD2022021);Six Talent Peaks Project in Jiangsu Province(WSN-022);Suzhou Clinical Medical Center for Anaesthesiology(Szlcyxzxj202102);Jiangsu Medical Association Anaesthesia Research Project(SYH-32021-0036(2021031));Suzhou Medical Health Science and Technology Innovation Project(SKY2022136);Jiangsu Provincial Colleges of Natural Science General Program(22KJD320002);Health Talent Plan Project in Suzhou(GSWS2022007);Gusu Health Talent Project of Soochow(GSWS2021062).
Sevoflurane induces developmental neurotoxicity in mice;however,the underlying mechanisms remain unclear.Triggering receptor expressed on myeloid cells 2(TREM2)is essential for microglia-mediated synaptic refinement d...
关键词：CA1 neurons Dendritic spines Developmental neurotoxicity MICROGLIA SEVOFLURANE TREM2 
Pichia pastoris composition expressed aerolysin mutant of Aeromonas veronii as an oral vaccine evaluated in zebrafish(Danio rerio)
《Marine Life Science & Technology》2024年第3期475-487,共13页Yuan-Yuan Yao Qing-Shuang Zhang Shu-Bin Liu Hong-Wei Yang Xing-Yu Chen Ya-Lin Yang Chen-Chen Gao Chao Ran Tsegay Teame Zhen Zhang Zhi-Gang Zhou 
funded by National Natural Sci-ence Foundation of China(NSFC 32303027);Agricultural Science and Technology Innovation Program(ASTIP)and Basal Research Fund(1610382023017)of the Chinese Academy of Agricultural Sciences;Project Team of Foshan National Hi-tech Industrial Development Zone Industrialization Entrepreneurial Teams Program(2320197000012);Beijing Innovation Consortium of Agriculture Research System(BAIC07-2023-11).
Vaccines are one of the most practical means to stop the spreading of Aeromonas veronii in aquaculture.In this study,virulence factor aerolysin mutant NTaer which has lost its hemolytic activity was used as a target a...
关键词：Aeromonas veronii Aerolysin mutant NTaer Oral vaccine Immune response Gut microbiota 
Pollen-expressed RLCKs control pollen tube burst
《Plant Communications》2024年第8期147-156,共10页Yin-Jiao Xu Ting Luo Peng-Min Zhou Wei-Qi Wang Wei-Cai Yang Hong-Ju Li 
supported by NSFC grants(31991203,32130032);the National Key Research and Development Program of China(2022YFF 1003500);the CAS Project for Young Scientists in Basic Research(no.YSBR-078);the Strategic Priority Research Program of the Chinese Academy of Science(XDA24020306)。
In angiosperms,the pollen tube enters the receptive synergid cell,where it ruptures to release its cytoplasm along with two sperm cells.This interaction is complex,and the exact signal transducers that trigger the bur...
关键词：Pollen tube burst RLCKs Calcium signaling/transport Double fertilization 
LncRNA MEG3 Inhibits the Epithelial-mesenchymal Transition of Bladder Cancer Cells through the Snail/E-cadherin Axis被引量：1
《Current Medical Science》2024年第4期726-734,共9页Liang WANG Ping WANG Bing LIU Hui ZHANG Cheng-cheng WEI Ming XIONG Gang LUO Miao WANG 
supported by the National Natural Science Foundation of China(Nos.82273443,81602234 and 81802538);the Natural Science Foundation of Hubei Province(Nos.2017CFB637 and 2023AFB1041).
Objective This study aimed to investigate the role of the long noncoding RNA(lncRNA)maternally expressed gene 3(MEG3)in the epithelial-mesenchymal transition(EMT)of bladder cancer cells and the potential mechanisms.Me...
关键词：long noncoding RNA bladder cancer maternally expressed gene 3 epithelial-mesenchymal transition SNAIL 
Chemokine-like factor 1 (CKLF1) is expressed in myocardial ischemia injury in vivo and in vitro
《BIOCELL》2024年第6期981-990,共10页JULING FENG HAODONG CHEN YANGBO LIU QIDI AI YANTAO YANG LEI ZHAO SHIFENG CHU NAIHONG CHEN 
This work was supported by the National Natural Science Foundation of China(81873026,82074044,81900488,and 81730096);the Beijing Natural Science Foundation(7192135);the Health and Family Planning Commission of Hunan Province(202104010694);the Natural Science Foundation of Hunan Province(2022JJ80028,2023JJ60369).
Introduction:Chemokine-like factor 1(CKLF1)is a chemokine that is overexpressed in several diseases.Our previousfindings revealed a significant increase in CKLF1 expression in the ischemic brain,suggesting its potential...
关键词：Chemokine-like factor 1 OVEREXPRESSION Myocardial infarction 
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